Lowell, Clifford A.

The multifaceted functions of neutrophils

Mayadas, T. N., Cullere, X., & Lowell, C. A. (2014) · Annual Review of Pathology: Mechanisms of Disease

Neutrophil, Myeloperoxidase and Oxidative MechanismsInflammation biomarkers and pathways

Cited by 1,356

A critical role for Syk in signal transduction and phagocytosis mediated by Fcγ receptors on macrophages

Crowley, M. T., Costello, P. S., Fitzer-Attas, C. J., Turner, M., Meng, F., Lowell, C., Tybulewicz, V. L. J., & DeFranco, A. L. (1997) · The Journal of Experimental Medicine

Phagocytosis and Immune RegulationMonoclonal and Polyclonal Antibodies Research

Cited by 506

Syk is required for integrin signaling in neutrophils

Mócsai, A., Zhou, M., Meng, F., Tybulewicz, V. L., & Lowell, C. A. (2002) · Immunity

Cell Adhesion Molecules ResearchNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 421

Receptor-Independent, Direct Membrane Binding Leads to Cell-Surface Lipid Sorting and Syk Kinase Activation in Dendritic Cells

Ng, G., Sharma, K., Ward, S. M., Desrosiers, M. D., Stephens, L. A., Schoel, W. M., Li, T., Lowell, C. A., Ling, C.-C., Amrein, M. W., et al. (2008) · Immunity

Immunotherapy and Immune ResponsesImmune Response and Inflammation

Cited by 276

Integrin signalling in neutrophils and macrophages

Berton, G., & Lowell, C. A. (1999) · Cellular Signalling

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 224

Src and Syk kinases: key regulators of phagocytic cell activation

Berton, G., Mócsai, A., & Lowell, C. A. (2005) · Trends in Immunology

Cytokine Signaling Pathways and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 214

Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens

Ma, J., Becker, C., Lowell, C. A., & Underhill, D. M. (2012) · Journal of Biological Chemistry

Autophagy in Disease and TherapyImmune Response and Inflammation

Cited by 198

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

Chen, Z., Shojaee, S., Buchner, M., Geng, H., Lee, J. W., Klemm, L., Titz, B., Graeber, T. G., Park, E., Tan, Y. X., et al. (2015) · Nature

Acute Lymphoblastic Leukemia researchT-cell and B-cell Immunology

Cited by 149

The Neutrophil Btk Signalosome Regulates Integrin Activation during Sterile Inflammation

Volmering, S., Block, H., Boras, M., Lowell, C. A., & Zarbock, A. (2016) · Immunity

Cell Adhesion Molecules ResearchNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 98

Role of Src kinases and Syk in Fcγ receptor-mediated phagocytosis and phagosome-lysosome fusion

Majeed, M., Caveggion, E., Lowell, C. A., & Berton, G. (2001) · Journal of Leukocyte Biology

Phagocytosis and Immune RegulationCellular transport and secretion

Cited by 97

Inhibition of β2 Integrin Receptor and Syk Kinase Signaling in Monocytes by the Src Family Kinase Fgr

Vines, C. M., Potter, J. W., Xu, Y., Geahlen, R. L., Costello, P. S., Tybulewicz, V. L., Lowell, C. A., Chang, P. W., Gresham, H. D., & Willman, C. L. (2001) · Immunity

Cell Adhesion Molecules ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 87

Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement

Alenghat, F. J., Baca, Q. J., Rubin, N. T., Pao, L. I., Matozaki, T., Lowell, C. A., Golan, D. E., Neel, B. G., & Swanson, K. D. (2012) · Journal of Cell Science

Cell Adhesion Molecules ResearchPhagocytosis and Immune Regulation

Cited by 58

FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection

Kerr, S. C., Fischer, G. J., Sinha, M., McCabe, O., Palmer, J. M., Choera, T., Yun Lim, F., Wimmerova, M., Carrington, S. D., Yuan, S., et al. (2016) · PLOS Pathogens

Antifungal resistance and susceptibilityGlycosylation and Glycoproteins Research

Cited by 53