Crabtree, Gerald R.

The mechanism of action of cyclosporin A and FK506

Schreiber, S. L., & Crabtree, G. R. (1992) · Immunology Today

Signaling Pathways in DiseaseT-cell and B-cell Immunology

Cited by 2,127

NFAT Signaling

Crabtree, G. R., & Olson, E. N. (2002) · Cell

Signaling Pathways in DiseaseNuclear Receptors and Signaling

Cited by 1,323

Chromatin remodelling during development

Ho, L., & Crabtree, G. R. (2010) · Nature

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,114

MicroRNA-mediated conversion of human fibroblasts to neurons

Yoo, A. S., Sun, A. X., Li, L., Shcheglovitov, A., Portmann, T., Li, Y., Lee-Messer, C., Dolmetsch, R. E., Tsien, R. W., & Crabtree, G. R. (2011) · Nature

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 989

ATP-dependent chromatin remodeling: genetics, genomics and mechanisms

Hargreaves, D. C., & Crabtree, G. R. (2011) · Cell Research

Chromatin Remodeling and CancerGenomics and Chromatin Dynamics

Cited by 923

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

Pugh, T. J., Weeraratne, S. D., Archer, T. C., Pomeranz Krummel, D. A., Auclair, D., Bochicchio, J., Carneiro, M. O., Carter, S. L., Cibulskis, K., Erlich, R. L., et al. (2012) · Nature

Glioma Diagnosis and TreatmentCancer Genomics and Diagnostics

Cited by 750

An Essential Switch in Subunit Composition of a Chromatin Remodeling Complex during Neural Development

Lessard, J., Wu, J. I., Ranish, J. A., Wan, M., Winslow, M. M., Staahl, B. T., Wu, H., Aebersold, R., Graef, I. A., & Crabtree, G. R. (2007) · Neuron

Chromatin Remodeling and CancerNeurogenesis and neuroplasticity mechanisms

Cited by 735

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21

Arron, J. R., Winslow, M. M., Polleri, A., Chang, C.-P., Wu, H., Gao, X., Neilson, J. R., Chen, L., Heit, J. J., Kim, S. K., et al. (2006) · Nature

Down syndrome and intellectual disability researchSignaling Pathways in Disease

Cited by 698

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

de la Pompa, J. L., Timmerman, L. A., Takimoto, H., Yoshida, H., Elia, A. J., Samper, E., Potter, J., Wakeham, A., Marengere, L., Langille, B. L., et al. (1998) · Nature

Congenital heart defects researchSignaling Pathways in Disease

Cited by 660

MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

Yoo, A. S., Staahl, B. T., Chen, L., & Crabtree, G. R. (2009) · Nature

Neurogenesis and neuroplasticity mechanismsChromatin Remodeling and Cancer

Cited by 645

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

Fraser, J. D., Irving, B. A., Crabtree, G. R., & Weiss, A. (1991) · Science

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 641

From neural development to cognition: unexpected roles for chromatin

Ronan, J. L., Wu, W., & Crabtree, G. R. (2013) · Nature Reviews Genetics

Genetics and Neurodevelopmental DisordersChromatin Remodeling and Cancer

Cited by 544

Chemically induced proximity in biology and medicine

Stanton, B. Z., Chory, E. J., & Crabtree, G. R. (2018) · Science

Gene Regulatory Network AnalysisProtein Degradation and Inhibitors

Cited by 475

Dynamics and Memory of Heterochromatin in Living Cells

Hathaway, N. A., Bell, O., Hodges, C., Miller, E. L., Neel, D. S., & Crabtree, G. R. (2012) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 446

Neurotrophins and Netrins Require Calcineurin/NFAT Signaling to Stimulate Outgrowth of Embryonic Axons

Graef, I. A., Wang, F., Charron, F., Chen, L., Neilson, J., Tessier-Lavigne, M., & Crabtree, G. R. (2003) · Cell

Axon Guidance and Neuronal SignalingNerve injury and regeneration

Cited by 379

A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis

Chang, C.-P., Neilson, J. R., Bayle, J. H., Gestwicki, J. E., Kuo, A., Stankunas, K., Graef, I. A., & Crabtree, G. R. (2004) · Cell

Congenital heart defects researchSignaling Pathways in Disease

Cited by 331

Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits

Platt, R. J., Zhou, Y., Slaymaker, I. M., Shetty, A. S., Weisbach, N. R., Kim, J.-A., Sharma, J., Desai, M., Sood, S., Kempton, H. R., et al. (2017) · Cell Reports

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 240

A CRISPR/Cas9-Engineered ARID1A -Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation

Lo, Y.-H., Kolahi, K. S., Du, Y., Chang, C.-Y., Krokhotin, A., Nair, A., Sobba, W. D., Karlsson, K., Jones, S. J., Longacre, T. A., et al. (2021) · Cancer Discovery

Chromatin Remodeling and CancerCRISPR and Genetic Engineering

Cited by 174

Calcineurin: a central controller of signalling in eukaryotes: Workshop on the Calcium/Calcineurin/NFAT Pathway: Regulation and Function

Aramburu, J., Heitman, J., & Crabtree, G. R. (2004) · The EMBO Reports

Signaling Pathways in DiseaseCalpain Protease Function and Regulation

Cited by 156

Systemic enhancement of serotonin signaling reverses social deficits in multiple mouse models for ASD

Walsh, J. J., Llorach, P., Cardozo Pinto, D. F., Wenderski, W., Christoffel, D. J., Salgado, J. S., Heifets, B. D., Crabtree, G. R., & Malenka, R. C. (2021) · Neuropsychopharmacology

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 56

PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape

Gamble, N., Bradu, A., Caldwell, J. A., McKeever, J., Bolonduro, O., Ermis, E., Kaiser, C., Kim, Y., Parks, B., Klemm, S., et al. (2024) · Nature Immunology

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 26