Montagne, Axel

Blood-Brain Barrier: From Physiology to Disease and Back

Sweeney, M. D., Zhao, Z., Montagne, A., Nelson, A. R., & Zlokovic, B. V. (2019) · Physiological Reviews

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 2,312

Blood-brain barrier breakdown in the aging human hippocampus

Montagne, A., Barnes, S. R., Sweeney, M. D., Halliday, M. R., Sagare, A. P., Zhao, Z., Toga, A. W., Jacobs, R. E., Liu, C. Y., Amezcua, L., et al. (2015) · Neuron

Barrier Structure and Function StudiesCerebrospinal fluid and hydrocephalus

Cited by 2,102

Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction

Nation, D. A., Sweeney, M. D., Montagne, A., Sagare, A. P., D’Orazio, L. M., Pachicano, M., Sepehrband, F., Nelson, A. R., Buennagel, D. P., Harrington, M. G., et al. (2019) · Nature Medicine

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 1,728

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

Montagne, A., Nation, D. A., Sagare, A. P., Barisano, G., Sweeney, M. D., Chakhoyan, A., Pachicano, M., Joe, E., Nelson, A. R., D’Orazio, L. M., et al. (2020) · Nature

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 1,281

Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease

Kisler, K., Nelson, A. R., Montagne, A., & Zlokovic, B. V. (2017) · Nature Reviews Neuroscience

Barrier Structure and Function StudiesNeurological Disease Mechanisms and Treatments

Cited by 1,243

The role of brain vasculature in neurodegenerative disorders

Sweeney, M. D., Kisler, K., Montagne, A., Toga, A. W., & Zlokovic, B. V. (2018) · Nature Neuroscience

Barrier Structure and Function StudiesNeurological Disease Mechanisms and Treatments

Cited by 998

Perivascular spaces in the brain: anatomy, physiology and pathology

Wardlaw, J. M., Benveniste, H., Nedergaard, M., Zlokovic, B. V., Mestre, H., Lee, H., Doubal, F. N., Brown, R., Ramirez, J., MacIntosh, B. J., et al. (2020) · Nature Reviews Neurology

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 870

Vascular dysfunction—The disregarded partner of Alzheimer's disease

Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., et al. (2019) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 711

Alzheimer’s disease: A matter of blood–brain barrier dysfunction?

Montagne, A., Zhao, Z., & Zlokovic, B. V. (2017) · Journal of Experimental Medicine

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 672

RETRACTED ARTICLE: Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

Montagne, A., Nikolakopoulou, A. M., Zhao, Z., Sagare, A. P., Si, G., Lazic, D., Barnes, S. R., Daianu, M., Ramanathan, A., Go, A., et al. (2018) · Nature Medicine

Cerebrovascular and genetic disordersBarrier Structure and Function Studies

Cited by 344

Brain imaging of neurovascular dysfunction in Alzheimer’s disease

Montagne, A., Nation, D. A., Pa, J., Sweeney, M. D., Toga, A. W., & Zlokovic, B. V. (2016) · Acta Neuropathologica

Barrier Structure and Function StudiesDementia and Cognitive Impairment Research

Cited by 239

APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β

Montagne, A., Nikolakopoulou, A. M., Huuskonen, M. T., Sagare, A. P., Lawson, E. J., Lazic, D., Rege, S. V., Grond, A., Zuniga, E., Barnes, S. R., et al. (2021) · Nature Aging

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 188

Blood–brain barrier link to human cognitive impairment and Alzheimer’s disease

Barisano, G., Montagne, A., Kisler, K., Schneider, J. A., Wardlaw, J. M., & Zlokovic, B. V. (2022) · Nature Cardiovascular Research

Barrier Structure and Function StudiesDementia and Cognitive Impairment Research

Cited by 157

Optimal acquisition and modeling parameters for accurate assessment of low Ktrans blood-brain barrier permeability using dynamic contrast-enhanced MRI: Optimal Parameters for Accurate Low Permeability DCE-MRI Estimation

Barnes, S. R., Ng, T. S. C., Montagne, A., Law, M., Zlokovic, B. V., & Jacobs, R. E. (2016) · Magnetic Resonance in Medicine

Advanced MRI Techniques and ApplicationsBarrier Structure and Function Studies

Cited by 115

Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling

Nikolakopoulou, A. M., Zhao, Z., Montagne, A., & Zlokovic, B. V. (2017) · PLOS ONE

Barrier Structure and Function StudiesAngiogenesis and VEGF in Cancer

Cited by 109

Interplay between Brain Pericytes and Endothelial Cells in Dementia

Procter, T. V., Williams, A., & Montagne, A. (2021) · The American Journal of Pathology

Barrier Structure and Function StudiesNeurological Disease Mechanisms and Treatments

Cited by 106

ROCKETSHIP: a flexible and modular software tool for the planning, processing and analysis of dynamic MRI studies

Barnes, S. R., Ng, T. S. C., Santa-Maria, N., Montagne, A., Zlokovic, B. V., & Jacobs, R. E. (2015) · BMC Medical Imaging

Advanced MRI Techniques and ApplicationsMRI in cancer diagnosis

Cited by 101

A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer’s disease

Tsartsalis, S., Sleven, H., Fancy, N., Wessely, F., Smith, A. M., Willumsen, N., Cheung, T. K. D., Rokicki, M. J., Chau, V., Ifie, E., et al. (2024) · Nature Communications

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 95

Ultra-sensitive molecular MRI of cerebrovascular cell activation enables early detection of chronic central nervous system disorders

Montagne, A., Gauberti, M., Macrez, R., Jullienne, A., Briens, A., Raynaud, J.-S., Louin, G., Buisson, A., Haelewyn, B., Docagne, F., et al. (2012) · NeuroImage

Advanced MRI Techniques and ApplicationsBarrier Structure and Function Studies

Cited by 70

Prenatal disruption of blood–brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation

Zhao, Q., Dai, W., Chen, H. Y., Jacobs, R. E., Zlokovic, B. V., Lund, B. T., Montagne, A., & Bonnin, A. (2022) · Proceedings of the National Academy of Sciences

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 52