MacRae, James I.

Structure and metal-dependent mechanism of peptidoglycan deacetylase, a streptococcal virulence factor

Blair, D. E., Schüttelkopf, A. W., MacRae, J. I., & van Aalten, D. M. F. (2005) · Proceedings of the National Academy of Sciences

Enzyme Structure and FunctionBiochemical and Structural Characterization

Cited by 230

Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers

Houlihan, C. F., Vora, N., Byrne, T., Lewer, D., Kelly, G., Heaney, J., Gandhi, S., Spyer, M. J., Beale, R., Cherepanov, P., et al. (2020) · The Lancet

SARS-CoV-2 and COVID-19 ResearchCOVID-19 epidemiological studies

Cited by 219

Vitamin D regulates microbiome-dependent cancer immunity

Giampazolias, E., Pereira da Costa, M., Lam, K. C., Lim, K. H. J., Cardoso, A., Piot, C., Chakravarty, P., Blasche, S., Patel, S., Biram, A., et al. (2024) · Science

Vitamin D Research StudiesCancer Immunotherapy and Biomarkers

Cited by 151

Endosymbiosis undone by stepwise elimination of the plastid in a parasitic dinoflagellate

Gornik, S. G., Febrimarsa, Cassin, A. M., MacRae, J. I., Ramaprasad, A., Rchiad, Z., McConville, M. J., Bacic, A., McFadden, G. I., Pain, A., et al. (2015) · Proceedings of the National Academy of Sciences

Protist diversity and phylogenyPhotosynthetic Processes and Mechanisms

Cited by 114

Single-cell resolved imaging reveals intra-tumor heterogeneity in glycolysis, transitions between metabolic states, and their regulatory mechanisms

Kondo, H., Ratcliffe, C. D. H., Hooper, S., Ellis, J., MacRae, J. I., Hennequart, M., Dunsby, C. W., Anderson, K. I., & Sahai, E. (2021) · Cell Reports

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 109

A palmitoyl transferase chemical–genetic system to map ZDHHC-specific S-acylation

Ocasio, C. A., Baggelaar, M. P., Sipthorp, J., Losada de la Lastra, A., Tavares, M., Volarić, J., Soudy, C., Storck, E. M., Houghton, J. W., Palma-Duran, S. A., et al. (2024) · Nature Biotechnology

Click Chemistry and ApplicationsLipid metabolism and biosynthesis

Cited by 56

The metabolic growth limitations of petite cells lacking the mitochondrial genome

Vowinckel, J., Hartl, J., Marx, H., Kerick, M., Runggatscher, K., Keller, M. A., Mülleder, M., Day, J., Weber, M., Rinnerthaler, M., et al. (2021) · Nature Metabolism

Mitochondrial Function and PathologyFungal and yeast genetics research

Cited by 48

A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite

Ramaprasad, A., Burda, P.-C., Calvani, E., Sait, A. J., Palma-Duran, S. A., Withers-Martinez, C., Hackett, F., Macrae, J., Collinson, L., Gilberger, T. W., et al. (2022) · eLife

Malaria Research and ControlLipid metabolism and biosynthesis

Cited by 18

Metabolic turnover and dynamics of modified ribonucleosides by 13 C labeling

Gameiro, P. A., Encheva, V., Dos Santos, M. S., MacRae, J. I., & Ule, J. (2021) · Journal of Biological Chemistry

RNA modifications and cancerRNA and protein synthesis mechanisms

Cited by 10

Metabolic turnover and dynamics of modified ribonucleosides by 13C labeling

Gameiro, P. A., Encheva, V., Dos Santos, M. S., MacRae, J. I., & Ule, J. (2021) · Journal of Biological Chemistry

RNA modifications and cancerRNA and protein synthesis mechanisms

Cited by 10

A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite

Ramaprasad, A., Burda, P.-C., Calvani, E., Sait, A., Palma-Duran, S. A., Withers-Martinez, C., Hackett, F., MacRae, J., Collinson, L., Gilberger, T.-W., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Malaria Research and ControlLipid metabolism and biosynthesis

Cited by 1