Risch, Neil

The Future of Genetic Studies of Complex Human Diseases

Risch, N., & Merikangas, K. (1996) · Science

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 5,355

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R., Ellis, M. C., Fullan, A., et al. (1996) · Nature Genetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 3,664

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

Corder, E. H., Saunders, A. M., Risch, N. J., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Rimmler, J. B., Locke, P. A., Conneally, P. M., Schmader, K. E., et al. (1994) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,920

Searching for genetic determinants in the new millennium

Risch, N. J. (2000) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,839

Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression: A Meta-analysis

Risch, N., Herrell, R., Lehner, T., Liang, K.-Y., Eaves, L., Hoh, J., Griem, A., Kovacs, M., Ott, J., & Merikangas, K. R. (2009) · JAMA

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 1,655

Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

Botstein, D., & Risch, N. (2003) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,503

Candidate-gene approaches for studying complex genetic traits: practical considerations

Tabor, H. K., Risch, N. J., & Myers, R. M. (2002) · Nature Reviews Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,076

A brief history of human disease genetics

Claussnitzer, M., Cho, J. H., Collins, R., Cox, N. J., Dermitzakis, E. T., Hurles, M. E., Kathiresan, S., Kenny, E. E., Lindgren, C. M., MacArthur, D. G., et al. (2020) · Nature

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 697

A Genomic Screen of Autism: Evidence for a Multilocus Etiology

Risch, N., Spiker, D., Lotspeich, L., Nouri, N., Hinds, D., Hallmayer, J., Kalaydjieva, L., McCague, P., Dimiceli, S., Pitts, T., et al. (1999) · The American Journal of Human Genetics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 684

The continuous performance test, identical pairs version (CPT-IP): I. new findings about sustained attention in normal families

Cornblatt, B. A., Risch, N. J., Faris, G., Friedman, D., & Erlenmeyer-Kimling, L. (1988) · Psychiatry Research

Schizophrenia research and treatmentCognitive Abilities and Testing

Cited by 682

Complex HLA-DR and -DQ Interactions Confer Risk of Narcolepsy-Cataplexy in Three Ethnic Groups

Mignot, E., Lin, L., Rogers, W., Honda, Y., Qiu, X., Lin, X., Okun, M., Hohjoh, H., Miki, T., Hsu, S. H., et al. (2001) · The American Journal of Human Genetics

Sleep and Wakefulness ResearchSleep and related disorders

Cited by 594

Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins

Tishkoff, S. A., Dietzsch, E., Speed, W., Pakstis, A. J., Kidd, J. R., Cheung, K., Bonné-Tamir, B., Santachiara-Benerecetti, A. S., Moral, P., Krings, M., et al. (1996) · Science

Forensic and Genetic ResearchGenetic diversity and population structure

Cited by 587

The Relative Power of Family-Based and Case-Control Designs for Linkage Disequilibrium Studies of Complex Human Diseases I. DNA Pooling

Risch, N., & Teng, J. (1998) · Genome Research

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 366

Behavioral phenotypic variation in autism multiplex families: Evidence for a continuous severity gradient

Spiker, D., Lotspeich, L. J., Dimiceli, S., Myers, R. M., & Risch, N. (2002) · American Journal of Medical Genetics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 193

Characterizing the admixed African ancestry of African Americans

Zakharia, F., Basu, A., Absher, D., Assimes, T. L., Go, A. S., Hlatky, M. A., Iribarren, C., Knowles, J. W., Li, J., Narasimhan, B., et al. (2009) · Genome Biology

Forensic and Genetic ResearchRace, Genetics, and Society

Cited by 185

Screening a large reference sample to identify very low frequency sequence variants: comparisons between two genes

Glatt, C. E., DeYoung, J. A., Delgado, S., Service, S. K., Giacomini, K. M., Edwards, R. H., Risch, N., & Freimer, N. B. (2001) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 154

Familial Recurrence of Autism Spectrum Disorder: Evaluating Genetic and Environmental Contributions

Risch, N., Hoffmann, T. J., Anderson, M., Croen, L. A., Grether, J. K., & Windham, G. C. (2014) · American Journal of Psychiatry

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 144

Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study

Jorgenson, E., Thai, K. K., Hoffmann, T. J., Sakoda, L. C., Kvale, M. N., Banda, Y., Schaefer, C., Risch, N., Mertens, J., Weisner, C., et al. (2017) · Molecular Psychiatry

Genetic Associations and EpidemiologyAlcohol Consumption and Health Effects

Cited by 136

Future of genetics of mood disorders research

Merikangas, K. R., Chakravarti, A., Moldin, S. O., Araj, H., Blangero, J., Burmeister, M., Crabbe, J. C., Depaulo, J. R., Foulks, E., Freimer, N. B., et al. (2002) · Biological Psychiatry

Genetic Associations and EpidemiologyBipolar Disorder and Treatment

Cited by 128

History Shaped the Geographic Distribution of Genomic Admixture on the Island of Puerto Rico

Via, M., Gignoux, C. R., Roth, L. A., Fejerman, L., Galanter, J., Choudhry, S., Toro-Labrador, G., Viera-Vera, J., Oleksyk, T. K., Beckman, K., et al. (2011) · PLoS ONE

Forensic and Genetic ResearchRace, Genetics, and Society

Cited by 105

Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans

Tang, H., Jorgenson, E., Gadde, M., Kardia, S. L. R., Rao, D. C., Zhu, X., Schork, N. J., Hanis, C. L., & Risch, N. (2006) · Human Genetics

Race, Genetics, and SocietyGenetic Associations and Epidemiology

Cited by 87

Implications of multilocus inheritance for gene-disease association studies

Risch, N. (2001) · Theoretical Population Biology

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 52

Evidence of Reproductive Stoppage in Families With Autism Spectrum Disorder: A Large, Population-Based Cohort Study

Hoffmann, T. J., Windham, G. C., Anderson, M., Croen, L. A., Grether, J. K., & Risch, N. (2014) · JAMA Psychiatry

Autism Spectrum Disorder ResearchFamily and Disability Support Research

Cited by 52