Brose, Nils

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface

Brose, N., Petrenko, A. G., Südhof, T. C., & Jahn, R. (1992) · Science

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 979

Synaptotagmin I functions as a calcium regulator of release probability

Fernández-Chacón, R., Königstorfer, A., Gerber, S. H., García, J., Matos, M. F., Stevens, C. F., Brose, N., Rizo, J., Rosenmund, C., & Südhof, T. C. (2001) · Nature

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 961

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Koopmans, F., van Nierop, P., Andres-Alonso, M., Byrnes, A., Cijsouw, T., Coba, M. P., Cornelisse, L. N., Farrell, R. J., Goldschmidt, H. L., Howrigan, D. P., et al. (2019) · Neuron

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

Cited by 938

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles

Augustin, I., Rosenmund, C., Südhof, T. C., & Brose, N. (1999) · Nature

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 787

Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses

Song, J.-Y., Ichtchenko, K., Südhof, T. C., & Brose, N. (1999) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 696

Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming

Varoqueaux, F., Sigler, A., Rhee, J.-S., Brose, N., Enk, C., Reim, K., & Rosenmund, C. (2002) · Proceedings of the National Academy of Sciences

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 619

Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins

Li, C., Ullrich, B., Zhang, J. Z., Anderson, R. G. W., Brose, N., & Südhof, T. C. (1995) · Nature

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 599

Activity-Dependent Validation of Excitatory versus Inhibitory Synapses by Neuroligin-1 versus Neuroligin-2

Chubykin, A. A., Atasoy, D., Etherton, M. R., Brose, N., Kavalali, E. T., Gibson, J. R., & Südhof, T. C. (2007) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 594

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

Jamain, S., Radyushkin, K., Hammerschmidt, K., Granon, S., Boretius, S., Varoqueaux, F., Ramanantsoa, N., Gallego, J., Ronnenberg, A., Winter, D., et al. (2008) · Proceedings of the National Academy of Sciences

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 556

β Phorbol Ester- and Diacylglycerol-Induced Augmentation of Transmitter Release Is Mediated by Munc13s and Not by PKCs

Rhee, J.-S., Betz, A., Pyott, S., Reim, K., Varoqueaux, F., Augustin, I., Hesse, D., Südhof, T. C., Takahashi, M., Rosenmund, C., et al. (2002) · Cell

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 500

Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming

Betz, A., Thakur, P., Junge, H. J., Ashery, U., Rhee, J.-S., Scheuss, V., Rosenmund, C., Rettig, J., & Brose, N. (2001) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 425

Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release

Betz, A., Ashery, U., Rickmann, M., Augustin, I., Neher, E., Südhof, T. C., Rettig, J., & Brose, N. (1998) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 425

Mammalian Homologues of Caenorhabditis elegans unc-13 Gene Define Novel Family of C2-domain Proteins

Brose, N., Hofmann, K., Hata, Y., & Südhof, T. C. (1995) · Journal of Biological Chemistry

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 412

The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones

Imig, C., Min, S.-W., Krinner, S., Arancillo, M., Rosenmund, C., Südhof, T. C., Rhee, J., Brose, N., & Cooper, B. H. (2014) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 389

A shared vesicular carrier allows synaptic corelease of GABA and glycine

Wojcik, S. M., Katsurabayashi, S., Guillemin, I., Friauf, E., Rosenmund, C., Brose, N., & Rhee, J.-S. (2006) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 374

Differential Control of the Releasable Vesicle Pools by SNAP-25 Splice Variants and SNAP-23

Sørensen, J. B., Nagy, G., Varoqueaux, F., Nehring, R. B., Brose, N., Wilson, M. C., & Neher, E. (2003) · Cell

Cellular transport and secretionExtracellular vesicles in disease

Cited by 364

Doc2b Is a High-Affinity Ca 2+ Sensor for Spontaneous Neurotransmitter Release

Groffen, A. J., Martens, S., Arazola, R. D., Cornelisse, L. N., Lozovaya, N., de Jong, A. P. H., Goriounova, N. A., Habets, R. L. P., Takai, Y., Borst, J. G., et al. (2010) · Science

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 313

Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity

Junge, H. J., Rhee, J.-S., Jahn, O., Varoqueaux, F., Spiess, J., Waxham, M. N., Rosenmund, C., & Brose, N. (2004) · Cell

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 290

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

Shin, O.-H., Lu, J., Rhee, J.-S., Tomchick, D. R., Pang, Z. P., Wojcik, S. M., Camacho-Perez, M., Brose, N., Machius, M., Rizo, J., et al. (2010) · Nature Structural & Molecular Biology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 243

CaMKII binding to GluN2B is critical during memory consolidation

Halt, A. R., Dallapiazza, R. F., Zhou, Y., Stein, I. S., Qian, H., Juntti, S., Wojcik, S., Brose, N., Silva, A. J., & Hell, J. W. (2012) · The EMBO Journal

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 243

Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25

Nagy, G., Reim, K., Matti, U., Brose, N., Binz, T., Rettig, J., Neher, E., & Sørensen, J. B. (2004) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 239

Dynamic Control of Synaptic Vesicle Replenishment and Short-Term Plasticity by Ca2+-Calmodulin-Munc13-1 Signaling

Lipstein, N., Sakaba, T., Cooper, B. H., Lin, K.-H., Strenzke, N., Ashery, U., Rhee, J.-S., Taschenberger, H., Neher, E., & Brose, N. (2013) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 165

Distribution and synaptic localization of immunocytochemically identified NMDA receptor subunit proteins in sensory-motor and visual cortices of monkey and human

Huntley, G., Vickers, J., Janssen, W., Brose, N., Heinemann, S., & Morrison, J. (1994) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism

Cited by 161