Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming

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Primary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis

Ménasché, G., Feldmann, J., Fischer, A., & Basile, G. D. S. (2005) · Immunological Reviews · doi:10.1111/j.0105-2896.2005.00224.x · Cited by 178 · see citing works

Interaction of ATP Sensor, cAMP Sensor, Ca2+ Sensor, and Voltage-dependent Ca2+ Channel in Insulin Granule Exocytosis

Shibasaki, T., Sunaga, Y., Fujimoto, K., Kashima, Y., & Seino, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m309068200 · Cited by 175 · see citing works

Presynaptic Mechanism Underlying cAMP-Dependent Synaptic Potentiation

Kaneko, M., & Takahashi, T. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0999-04.2004 · Cited by 183 · see citing works

UNC-13 and UNC-10/Rim Localize Synaptic Vesicles to Specific Membrane Domains

Weimer, R., Gracheva, E. O., Meyrignac, O., Miller, K. G., Richmond, J., & Bessereau, J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2350-06.2006 · Cited by 169 · see citing works

Dynamic Control of Synaptic Vesicle Replenishment and Short-Term Plasticity by Ca2+-Calmodulin-Munc13-1 Signaling

Lipstein, N., Sakaba, T., Cooper, B. H., Lin, K.-H., Strenzke, N., Ashery, U., Rhee, J.-S., Taschenberger, H., Neher, E., & Brose, N. (2013) · Neuron · doi:10.1016/j.neuron.2013.05.011 · Cited by 165 · see citing works

A minimal domain responsible for Munc13 activity

Basu, J., Shen, N., Dulubova, I., Lu, J., Guan, R., Guryev, O., Grishin, N. V., Rosenmund, C., & Rizo, J. (2005) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1001 · Cited by 213 · see citing works

Quantitative Analysis of Calcium-Dependent Vesicle Recruitment and Its Functional Role at the Calyx of Held Synapse

Hosoi, N., Sakaba, T., & Neher, E. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4122-07.2007 · Cited by 154 · see citing works

How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs

Acuna, C., Liu, X., & Südhof, T. C. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.042 · Cited by 154 · see citing works

Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release.

Calakos, N., Schoch, S., Südhof, T., & Malenka, R. (2004) · Neuron · doi:10.1016/j.neuron.2004.05.014 · Cited by 173 · see citing works

Distinct Initial SNARE Configurations Underlying the Diversity of Exocytosis

Kasai, H., Takahashi, N., & Tokumaru, H. (2012) · Physiological Reviews · doi:10.1152/physrev.00007.2012 · Cited by 150 · see citing works

Identification of the minimal protein domain required for priming activity of Munc13-1

Stevens, D. R., Wu, Z.-X., Matti, U., Junge, H. J., Schirra, C., Becherer, U., Wojcik, S. M., Brose, N., & Rettig, J. (2005) · Current Biology · doi:10.1016/j.cub.2005.10.055 · Cited by 149 · see citing works

Molecular Anatomy of the Hair Cell's Ribbon Synapse

Uthaiah, R. C., & Hudspeth, A. J. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1014-10.2010 · Cited by 148 · see citing works

Molecular mechanisms of active zone function

Rosenmund, C., Rettig, J., & Brose, N. (2003) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2003.09.011 · Cited by 143 · see citing works

Factors regulating the abundance and localization of synaptobrevin in the plasma membrane

Dittman, J. S., & Kaplan, J. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600784103 · Cited by 148 · see citing works

Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking

Wang, S. S. H., Held, R. G., Wong, M. Y., Liu, C., Karakhanyan, A., & Kaeser, P. S. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.005 · Cited by 143 · see citing works

Neurobiology with Caged Calcium

Ellis‐Davies, G. C. R. (2008) · Chemical Reviews · doi:10.1021/cr078210i · Cited by 143 · see citing works

Divergent and convergent signaling by the diacylglycerol second messenger pathway in mammals

Brose, N., Betz, A., & Wegmeyer, H. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.05.006 · Cited by 140 · see citing works

Presynaptic long-term plasticity

Yang, Y., & Calakos, N. (2013) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2013.00008 · Cited by 135 · see citing works

Extensive Remodeling of the Presynaptic Cytomatrix upon Homeostatic Adaptation to Network Activity Silencing

Lazarevic, V., Schöne, C., Heine, M., Gundelfinger, E. D., & Fejtová, A. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2088-11.2011 · Cited by 126 · see citing works

Tuning exocytosis for speed: fast and slow modes

Martin, T. F. J. (2003) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(03)00093-4 · Cited by 132 · see citing works

Structural Basis for a Munc13–1 Homodimer to Munc13–1/RIM Heterodimer Switch

Lu, J., Machius, M., Dulubova, I., Dai, H., Südhof, T. C., Tomchick, D. R., & Rizo, J. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040192 · Cited by 132 · see citing works

Contact-induced clustering of syntaxin and munc18 docks secretory granules at the exocytosis site

Gandasi, N. R., & Barg, S. (2014) · Nature Communications · doi:10.1038/ncomms4914 · Cited by 130 · see citing works

Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats

Czéh, B., Vardya, I., Varga, Z., Febbraro, F., Csabai, D., Martis, L., Højgaard, K., Henningsen, K., Bouzinova, E. V., Miseta, A., et al. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00148 · Cited by 129 · see citing works

Evolutionarily Conserved Multiple C2 Domain Proteins with Two Transmembrane Regions (MCTPs) and Unusual Ca2+ Binding Properties*

Shin, O., Han, W., Wang, Y., & Südhof, T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m407305200 · Cited by 116 · see citing works

The molecular machinery of synaptic vesicle exocytosis

Li, L., & Chin, L. (2003) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-2240-7 · Cited by 126 · see citing works

Relating structure and function of inner hair cell ribbon synapses

Wichmann, C., & Moser, T. (2015) · Cell and Tissue Research · doi:10.1007/s00441-014-2102-7 · Cited by 123 · see citing works

Redundant functions of RIM1α and RIM2α in Ca2+‐triggered neurotransmitter release

Schoch, S., Mittelstaedt, T., Kaeser, P. S., Padgett, D., Feldmann, N., Chevaleyre, V., Castillo, P. E., Hammer, R. E., Han, W., Schmitz, F., et al. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601425 · Cited by 126 · see citing works

Calcium-dependent regulation of exocytosis

Barclay, J. W., Morgan, A., & Burgoyne, R. D. (2005) · Cell Calcium · doi:10.1016/j.ceca.2005.06.012 · Cited by 126 · see citing works

Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN

Xu, J., Camacho, M., Xu, Y., Esser, V., Liu, X., Trimbuch, T., Pan, Y.-Z., Ma, C., Tomchick, D. R., Rosenmund, C., et al. (2017) · eLife · doi:10.7554/elife.22567 · Cited by 119 · see citing works

Synapsin IIa Controls the Reserve Pool of Glutamatergic Synaptic Vesicles

Gitler, D., Cheng, Q., Greengard, P., & Augustine, G. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0924-08.2008 · Cited by 119 · see citing works

Regulation of Insulin Exocytosis by Munc13-1

Sheu, L., Pasyk, E. A., Ji, J., Huang, X., Gao, X., Varoqueaux, F., Brose, N., & Gaisano, H. Y. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303203200 · Cited by 118 · see citing works

SAD: A Presynaptic Kinase Associated with Synaptic Vesicles and the Active Zone Cytomatrix that Regulates Neurotransmitter Release

Inoue, E., Mochida, S., Takagi, H., Higa, S., Deguchi‐Tawarada, M., Takao‐Rikitsu, E., Inoue, M., Yao, I., Takeuchi, K., Kitajima, I., et al. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.018 · Cited by 113 · see citing works

Membrane Fusion in Eukaryotic Cells

Mayer, A. (2002) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.18.032202.114809 · Cited by 115 · see citing works

An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury

Hilton, B. J., Husch, A., Schaffran, B., Lin, T.-C., Burnside, E. R., Dupraz, S., Schelski, M., Kim, J., Müller, J. A., Schoch, S., et al. (2022) · Neuron · doi:10.1016/j.neuron.2021.10.007 · Cited by 116 · see citing works

Mechanisms of neuromodulatory volume transmission

Özçete, Ö. D., Banerjee, A., & Kaeser, P. S. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02608-3 · Cited by 123 · see citing works

RIM genes differentially contribute to organizing presynaptic release sites

Kaeser, P. S., Deng, L., Fan, M., & Südhof, T. C. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1209318109 · Cited by 115 · see citing works

Munc13‐2 −/− baseline secretion defect reveals source of oligomeric mucins in mouse airways

Zhu, Y., Ehré, C., Abdullah, L. H., Sheehan, J. K., Roy, M. G., Evans, C. M., Dickey, B. F., & Davis, C. W. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2007.149310 · Cited by 114 · see citing works

Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder

Lipstein, N., Verhoeven‐Duif, N. M., Michelassi, F. E., Calloway, N. T., van Hasselt, P. M., Pienkowska, K., van Haaften, G. W., van Haelst, M. M., Empelen, R. V., Cuppen, I., et al. (2017) · Journal of Clinical Investigation · doi:10.1172/jci90259 · Cited by 111 · see citing works

Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins☆☆Sequence data from this article have been deposited with the GenBank Data Library under Accession Nos. AF548738 and AF548739.

Wang, Y., & Südhof, T. C. (2003) · Genomics · doi:10.1016/s0888-7543(02)00024-1 · Cited by 112 · see citing works

Functional regions of the presynaptic cytomatrix protein bassoon: significance for synaptic targeting and cytomatrix anchoring

Dresbach, T., Hempelmann, A., Spilker, C., Dieck, S. T., Altrock, W. D., Zuschratter, W., Garner, C. C., & Gundelfinger, E. D. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00015-0 · Cited by 113 · see citing works

The RIM1 mutation associated with an autosomal dominant cone-rod dystrophy, CORD7, alters effects of RIM1 on VDCC currents

Miki, T., Kiyonaka, S., Uriu, Y., Wakamori, M., Mori, E., Itakura, M., Takahashi, M., Campbell, K. P., & Mori, Y. (2007) · Neuroscience Research · doi:10.1016/j.neures.2007.06.830

Disentangling the roles of RIM and Munc13 in synaptic vesicle localization and neurotransmission

Zarebidaki, F., Camacho, M., Brockmann, M. M., Trimbuch, T., Herman, M. A., & Rosenmund, C. (2020) · The Journal of Neuroscience · doi:10.1523/jneurosci.1922-20.2020 · Cited by 37 · see citing works

RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13

Deng, L., Kaeser, P. S., Xu, W., & Südhof, T. C. (2011) · Neuron · doi:10.1016/j.neuron.2011.01.005 · Cited by 287 · see citing works

The roles of RIM and Munc13 in the presynaptic terminal of murine hippocampal neurons

Zarebidaki, F. (2022) · doi:10.17169/refubium-34094

Binding to Rab3A-interacting Molecule RIM Regulates the Presynaptic Recruitment of Munc13-1 and ubMunc13-2

Andrews-Zwilling, Y. S., Kawabe, H., Reim, K., Varoqueaux, F., & Brose, N. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601421200 · Cited by 103 · see citing works