Egli, Dieter

A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

Ichida, J. K., Blanchard, J., Lam, K., Son, E. Y., Chung, J. E., Egli, D., Loh, K. M., Carter, A. C., Di Giorgio, F. P., Koszka, K., et al. (2009) · Cell Stem Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 808

Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos

Zuccaro, M. V., Xu, J., Mitchell, C., Marin, D., Zimmerman, R., Rana, B., Weinstein, E., King, R. T., Palmerola, K. L., Smith, M. E., et al. (2020) · Cell

CRISPR and Genetic EngineeringDNA Repair Mechanisms

Cited by 303

BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity

Shakya, R., Reid, L. J., Reczek, C. R., Cole, F., Egli, D., Lin, C.-S., deRooij, D. G., Hirsch, S., Ravi, K., Hicks, J. B., et al. (2011) · Science

BRCA gene mutations in cancerCancer-related Molecular Pathways

Cited by 244

Combined inhibition of DYRK1A, SMAD, and trithorax pathways synergizes to induce robust replication in adult human beta cells

Wang, P., Karakose, E., Liu, H., Swartz, E., Ackeifi, C., Zlatanic, V., Wilson, J., González, B. J., Bender, A., Takane, K. K., et al. (2019) · Cell Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 162

Inter-homologue repair in fertilized human eggs?

Egli, D., Zuccaro, M. V., Kosicki, M., Church, G. M., Bradley, A., & Jasin, M. (2018) · Nature

CRISPR and Genetic EngineeringDNA Repair Mechanisms

Cited by 111

Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq

Weissbein, U., Schachter, M., Egli, D., & Benvenisty, N. (2016) · Nature Communications

Genomic variations and chromosomal abnormalitiesGenomics and Phylogenetic Studies

Cited by 64

GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions

Agudo, J., Ruzo, A., Park, E. S., Sweeney, R., Kana, V., Wu, M., Zhao, Y., Egli, D., Merad, M., & Brown, B. D. (2015) · Nature Biotechnology

T-cell and B-cell ImmunologyAnimal Genetics and Reproduction

Cited by 64