Bartel, David P.

Poly(A)-tail profiling reveals an embryonic switch in translational control

Subtelny, A. O., Eichhorn, S. W., Chen, G. R., Sive, H., & Bartel, D. P. (2014) · Nature

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 664

Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing

Shin, C., Nam, J.-W., Farh, K. K.-H., Chiang, H. R., Shkumatava, A., & Bartel, D. P. (2010) · Molecular Cell

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 611

RNAi in Budding Yeast

Drinnenberg, I. A., Weinberg, D. E., Xie, K. T., Mower, J. P., Wolfe, K. H., Fink, G. R., & Bartel, D. P. (2009) · Science

RNA Interference and Gene DeliveryRNA Research and Splicing

Cited by 524

Most Caenorhabditis elegans microRNAs Are Individually Not Essential for Development or Viability

Miska, E. A., Alvarez-Saavedra, E., Abbott, A. L., Lau, N. C., Hellman, A. B., McGonagle, S. M., Bartel, D. P., Ambros, V. R., & Horvitz, H. R. (2007) · PLoS Genetics

MicroRNA in disease regulationDevelopmental Biology and Gene Regulation

Cited by 484

Structurally Complex and Highly Active RNA Ligases Derived from Random RNA Sequences

Ekland, E. H., Szostak, J. W., & Bartel, D. P. (1995) · Science

RNA and protein synthesis mechanismsRNA regulation and disease

Cited by 422

Improved ribosome-footprint and mRNA measurements provide insights into dynamics and regulation of yeast translation

Weinberg, D. E., Shah, P., Eichhorn, S. W., Hussmann, J. A., Plotkin, J. B., & Bartel, D. P. (2015) · Cell Reports

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 392

Improved ribosome-footprint and mRNA measurements provide insights into dynamics and regulation of yeast translation

Weinberg, D. E., Shah, P., Eichhorn, S. W., Hussmann, J. A., Plotkin, J. B., & Bartel, D. P. (2016) · Cell Reports

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 392

One sequence, two ribozymes: implications for the emergence of new ribozyme folds

Schultes, E. A., & Bartel, D. P. (2000) · Science

RNA and protein synthesis mechanismsOrigins and Evolution of Life

Cited by 364

Impact of MicroRNA levels, target-site complementarity, and cooperativity on competing endogenous RNA-regulated gene expression

Denzler, R., McGeary, S. E., Title, A. C., Agarwal, V., Bartel, D. P., & Stoffel, M. (2016) · Molecular Cell

Cancer-related molecular mechanisms researchMicroRNA in disease regulation

Cited by 340

RNA-catalysed RNA polymerization using nucleoside triphosphates

Ekland, E. H., & Bartel, D. P. (1996) · Nature

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 250

The Dynamics of Cytoplasmic mRNA Metabolism

Eisen, T. J., Eichhorn, S. W., Subtelny, A. O., Lin, K. S., McGeary, S. E., Gupta, S., & Bartel, D. P. (2019) · Molecular Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 178

The Dynamics of Cytoplasmic mRNA Metabolism

Eisen, T. J., Eichhorn, S. W., Subtelny, A. O., Lin, K. S., McGeary, S. E., Gupta, S., & Bartel, D. P. (2020) · Molecular Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 177

Crystal Structure of the Catalytic Core of an RNA-Polymerase Ribozyme

Shechner, D. M., Grant, R. A., Bagby, S. C., Koldobskaya, Y., Piccirilli, J. A., & Bartel, D. P. (2009) · Science

RNA and protein synthesis mechanismsOrigins and Evolution of Life

Cited by 136

Nonenzymatic, template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3′-5′ phosphodiester bonds

Rohatgi, R., Bartel, D. P., & Szostak, J. W. (1996) · Journal of the American Chemical Society

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 134

Global analyses of the dynamics of mammalian microRNA metabolism

Kingston, E. R., & Bartel, D. P. (2019) · Genome Research

MicroRNA in disease regulationRNA Research and Splicing

Cited by 133

Global analyses of the dynamics of mammalian microRNA metabolism

Kingston, E. R., & Bartel, D. P. (2019) · Genome Research

MicroRNA in disease regulationRNA Research and Splicing

Cited by 133

Pairing to the microRNA 3′ region occurs through two alternative binding modes, with affinity shaped by nucleotide identity as well as pairing position

McGeary, S. E., Bisaria, N., & Bartel, D. P. (2021) · eLife

MicroRNA in disease regulationRNA Research and Splicing

Cited by 69

New ligase-derived RNA polymerase ribozymes

LAWRENCE, M. S., & BARTEL, D. P. (2005) · RNA

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 68

Processivity of Ribozyme-Catalyzed RNA Polymerization

Lawrence, M. S., & Bartel, D. P. (2003) · Biochemistry

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 62

The structural basis of RNA-catalyzed RNA polymerization

Shechner, D. M., & Bartel, D. P. (2011) · Nature Structural & Molecular Biology

RNA and protein synthesis mechanismsOrigins and Evolution of Life

Cited by 48

Improved polymerase ribozyme efficiency on hydrophobic assemblies

Müller, U. F., & Bartel, D. P. (2008) · RNA

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 46

Synthetic shuffling and in vitro selection reveal the rugged adaptive fitness landscape of a kinase ribozyme

Curtis, E. A., & Bartel, D. P. (2013) · RNA

RNA and protein synthesis mechanismsEvolution and Genetic Dynamics

Cited by 35

The structural basis for RNA slicing by human Argonaute2

Mohamed, A. A., Wang, P. Y., Bartel, D. P., & Vos, S. M. (2024) · Cell Reports

RNA Interference and Gene DeliveryCRISPR and Genetic Engineering

Cited by 32

The structural basis for RNA slicing by human Argonaute2

Mohamed, A. A., Wang, P. Y., Bartel, D. P., & Vos, S. M. (2025) · Cell Reports

RNA Interference and Gene DeliveryCRISPR and Genetic Engineering

Cited by 32