Duman, Ronald S.

The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses

Iwata, M., Ota, K. T., & Duman, R. S. (2013) · Brain, Behavior, and Immunity

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 580

Role of Neurotrophic Factors in the Etiology and Treatment of Mood Disorders

Duman, R. S. (2004) · NeuroMolecular Medicine

Treatment of Major DepressionNerve injury and regeneration

Cited by 537

Signaling pathways underlying the rapid antidepressant actions of ketamine

Duman, R. S., Li, N., Liu, R.-J., Duric, V., & Aghajanian, G. (2012) · Neuropharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 537

Lower synaptic density is associated with depression severity and network alterations

Holmes, S. E., Scheinost, D., Finnema, S. J., Naganawa, M., Davis, M. T., DellaGioia, N., Nabulsi, N., Matuskey, D., Angarita, G. A., Pietrzak, R. H., et al. (2019) · Nature Communications

Treatment of Major DepressionFunctional Brain Connectivity Studies

Cited by 484

5-HT2AReceptor-Mediated Regulation of Brain-Derived Neurotrophic Factor mRNA in the Hippocampus and the Neocortex

Vaidya, V. A., Marek, G. J., Aghajanian, G. K., & Duman, R. S. (1997) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorPsychedelics and Drug Studies

Cited by 479

Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice

Duman, C. H., Schlesinger, L., Russell, D. S., & Duman, R. S. (2008) · Brain Research

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 465

Regulation of adult neurogenesis by antidepressant treatment

Duman, R. (2001) · Neuropsychopharmacology

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 463

Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole

Banasr, M., Chowdhury, G. M. I., Terwilliger, R., Newton, S. S., Duman, R. S., Behar, K. L., & Sanacora, G. (2010) · Molecular Psychiatry

Treatment of Major DepressionTryptophan and brain disorders

Cited by 458

Ketamine: A Paradigm Shift for Depression Research and Treatment

Krystal, J. H., Abdallah, C. G., Sanacora, G., Charney, D. S., & Duman, R. S. (2019) · Neuron

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 455

VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants

Warner-Schmidt, J. L., & Duman, R. S. (2007) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 438

Blocking TGF-β–Smad2/3 innate immune signaling mitigates Alzheimer-like pathology

Town, T., Laouar, Y., Pittenger, C., Mori, T., Szekely, C. A., Tan, J., Duman, R. S., & Flavell, R. A. (2008) · Nature Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 422

Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics

Abdallah, C. G., Sanacora, G., Duman, R. S., & Krystal, J. H. (2015) · Annual Review of Medicine

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 422

A negative regulator of MAP kinase causes depressive behavior

Duric, V., Banasr, M., Licznerski, P., Schmidt, H. D., Stockmeier, C. A., Simen, A. A., Newton, S. S., & Duman, R. S. (2010) · Nature Medicine

Treatment of Major DepressionProtein Tyrosine Phosphatases

Cited by 412

Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond

Krystal, J. H., Sanacora, G., & Duman, R. S. (2013) · Biological Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 406

Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex

Liu, R.-J., Lee, F. S., Li, X.-Y., Bambico, F., Duman, R. S., & Aghajanian, G. K. (2012) · Biological Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 403

Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models

Schmidt, H. D., & Duman, R. S. (2010) · Neuropsychopharmacology

Treatment of Major DepressionNerve injury and regeneration

Cited by 403

Cortical GABAergic Dysfunction in Stress and Depression: New Insights for Therapeutic Interventions

Fogaça, M. V., & Duman, R. S. (2019) · Frontiers in Cellular Neuroscience

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 396

Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor

Iwata, M., Ota, K. T., Li, X.-Y., Sakaue, F., Li, N., Dutheil, S., Banasr, M., Duric, V., Yamanashi, T., Kaneko, K., et al. (2016) · Biological Psychiatry

Adenosine and Purinergic SignalingTryptophan and brain disorders

Cited by 387

Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat

Kodama, M., Fujioka, T., & Duman, R. S. (2004) · Biological Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 387

Prefrontal cortex circuits in depression and anxiety: contribution of discrete neuronal populations and target regions

Hare, B. D., & Duman, R. S. (2020) · Molecular Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 366

Synaptic plasticity and mood disorders

Duman, R. S. (2002) · Molecular Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 363

A neurotrophic hypothesis of depression: role of synaptogenesis in the actions of NMDA receptor antagonists

Duman, R. S., & Li, N. (2012) · Philosophical Transactions of the Royal Society B: Biological Sciences

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 362

Pathophysiology of depression: the concept of synaptic plasticity

Duman, R. S. (2002) · European Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 361

High-Fat Diet Induced Anxiety and Anhedonia: Impact on Brain Homeostasis and Inflammation

Dutheil, S., Ota, K. T., Wohleb, E. S., Rasmussen, K., & Duman, R. S. (2016) · Neuropsychopharmacology

Tryptophan and brain disordersTreatment of Major Depression

Cited by 355