Barreiro, Luis B.

Defining trained immunity and its role in health and disease

Netea, M. G., Domínguez-Andrés, J., Barreiro, L. B., Chavakis, T., Divangahi, M., Fuchs, E., Joosten, L. A. B., van der Meer, J. W. M., Mhlanga, M. M., Mulder, W. J. M., et al. (2020) · Nature Reviews Immunology

Immune responses and vaccinationsImmune Response and Inflammation

Cited by 2,690

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis

Kaufmann, E., Sanz, J., Dunn, J. L., Khan, N., Mendonça, L. E., Pacis, A., Tzelepis, F., Pernet, E., Dumaine, A., Grenier, J.-C., et al. (2018) · Cell

Immune responses and vaccinationsTuberculosis Research and Epidemiology

Cited by 1,191

Natural selection has driven population differentiation in modern humans

Barreiro, L. B., Laval, G., Quach, H., Patin, E., & Quintana-Murci, L. (2008) · Nature Genetics

Forensic and Genetic ResearchEvolution and Genetic Dynamics

Cited by 605

Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens

Nédélec, Y., Sanz, J., Baharian, G., Szpiech, Z. A., Pacis, A., Dumaine, A., Grenier, J.-C., Freiman, A., Sams, A. J., Hebert, S., et al. (2016) · Cell

Genetic Associations and EpidemiologyEvolution and Genetic Dynamics

Cited by 512

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host

Meisel, M., Hinterleitner, R., Pacis, A., Chen, L., Earley, Z. M., Mayassi, T., Pierre, J. F., Ernest, J. D., Galipeau, H. J., Thuille, N., et al. (2018) · Nature

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 406

Social status alters immune regulation and response to infection in macaques

Snyder-Mackler, N., Sanz, J., Kohn, J. N., Brinkworth, J. F., Morrow, S., Shaver, A. O., Grenier, J.-C., Pique-Regi, R., Johnson, Z. P., Wilson, M. E., et al. (2016) · Science

Stress Responses and CortisolHealth disparities and outcomes

Cited by 318

Seasonal Variation in Human Gut Microbiome Composition

Davenport, E. R., Mizrahi-Man, O., Michelini, K., Barreiro, L. B., Ober, C., & Gilad, Y. (2014) · PLoS ONE

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 314

Social environment is associated with gene regulatory variation in the rhesus macaque immune system

Tung, J., Barreiro, L. B., Johnson, Z. P., Hansen, K. D., Michopoulos, V., Toufexis, D., Michelini, K., Wilson, M. E., & Gilad, Y. (2012) · Proceedings of the National Academy of Sciences

Stress Responses and CortisolAnimal Behavior and Reproduction

Cited by 277

Gut microbiome heritability is nearly universal but environmentally contingent

Grieneisen, L., Dasari, M., Gould, T. J., Björk, J. R., Grenier, J.-C., Yotova, V., Jansen, D., Gottel, N., Gordon, J. B., Learn, N. H., et al. (2021) · Science

Gut microbiota and healthAnimal Behavior and Reproduction

Cited by 243

IL-15, gluten and HLA-DQ8 drive tissue destruction in coeliac disease

Abadie, V., Kim, S. M., Lejeune, T., Palanski, B. A., Ernest, J. D., Tastet, O., Voisine, J., Discepolo, V., Marietta, E. V., Hawash, M. B. F., et al. (2020) · Nature

Celiac Disease Research and ManagementWheat and Barley Genetics and Pathology

Cited by 231

Evolutionary genetic dissection of human interferons

Manry, J., Laval, G., Patin, E., Fornarino, S., Itan, Y., Fumagalli, M., Sironi, M., Tichit, M., Bouchier, C., Casanova, J.-L., et al. (2011) · Journal of Experimental Medicine

interferon and immune responsesEvolution and Genetic Dynamics

Cited by 176

Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans

Sams, A. J., Dumaine, A., Nédélec, Y., Yotova, V., Alfieri, C., Tanner, J. E., Messer, P. W., & Barreiro, L. B. (2016) · Genome Biology

Pleistocene-Era Hominins and ArchaeologyEvolution and Genetic Dynamics

Cited by 140

Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers

Perry, G. H., Foll, M., Grenier, J.-C., Patin, E., Nédélec, Y., Pacis, A., Barakatt, M., Gravel, S., Zhou, X., Nsobya, S. L., et al. (2014) · Proceedings of the National Academy of Sciences

Forensic and Genetic ResearchGenetic Associations and Epidemiology

Cited by 105

Formulating a historical and demographic model of recent human evolution based on resequencing data from noncoding regions

Laval, G., Patin, E., Barreiro, L. B., & Quintana-Murci, L. (2010) · PLoS ONE

Forensic and Genetic ResearchGenetic diversity and population structure

Cited by 93

Signatures of Purifying and Local Positive Selection in Human miRNAs

Quach, H., Barreiro, L. B., Laval, G., Zidane, N., Patin, E., Kidd, K. K., Kidd, J. R., Bouchier, C., Veuille, M., Antoniewski, C., et al. (2009) · The American Journal of Human Genetics

Evolution and Genetic DynamicsGenetic Associations and Epidemiology

Cited by 85

Primate innate immune responses to bacterial and viral pathogens reveals an evolutionary trade-off between strength and specificity

Hawash, M. B. F., Sanz-Remón, J., Grenier, J.-C., Kohn, J., Yotova, V., Johnson, Z., Lanford, R. E., Brinkworth, J. F., & Barreiro, L. B. (2021) · Proceedings of the National Academy of Sciences

Immune Response and Inflammationinterferon and immune responses

Cited by 56

A signature of Neanderthal introgression on molecular mechanisms of environmental responses

Findley, A. S., Zhang, X., Boye, C., Lin, Y. L., Kalita, C. A., Barreiro, L., Lohmueller, K. E., Pique-Regi, R., & Luca, F. (2021) · PLoS Genetics

Pleistocene-Era Hominins and ArchaeologyGenetic Associations and Epidemiology

Cited by 14