Rammensee, Hans-Georg

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

Gubin, M. M., Zhang, X., Schuster, H., Caron, E., Ward, J. P., Noguchi, T., Ivanova, Y., Hundal, J., Arthur, C. D., Krebber, W.-J., et al. (2014) · Nature

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 1,974

Actively personalized vaccination trial for newly diagnosed glioblastoma

Hilf, N., Kuttruff-Coqui, S., Frenzel, K., Bukur, V., Stevanović, S., Gouttefangeas, C., Platten, M., Tabatabai, G., Dutoit, V., van der Burg, S. H., et al. (2019) · Nature

Glioma Diagnosis and TreatmentImmunotherapy and Immune Responses

Cited by 938

SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition

Nelde, A., Bilich, T., Heitmann, J. S., Maringer, Y., Salih, H. R., Roerden, M., Lübke, M., Bauer, J., Rieth, J., Wacker, M., et al. (2021) · Nature Immunology

vaccines and immunoinformatics approachesSARS-CoV-2 and COVID-19 Research

Cited by 582

Direct Injection of Protamine-protected mRNA: Results of a Phase 1/2 Vaccination Trial in Metastatic Melanoma Patients

Weide, B., Pascolo, S., Scheel, B., Derhovanessian, E., Pflugfelder, A., Eigentler, T. K., Pawelec, G., Hoerr, I., Rammensee, H.-G., & Garbe, C. (2009) · Journal of Immunotherapy

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 378

Results of the First Phase I/II Clinical Vaccination Trial With Direct Injection of mRNA

Weide, B., Carralot, J.-P., Reese, A., Scheel, B., Eigentler, T. K., Hoerr, I., Rammensee, H.-G., Garbe, C., & Pascolo, S. (2008) · Journal of Immunotherapy

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 261

HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy

Marcu, A., Bichmann, L., Kuchenbecker, L., Kowalewski, D. J., Freudenmann, L. K., Backert, L., Mühlenbruch, L., Szolek, A., Lübke, M., Wagner, P., et al. (2021) · Journal for ImmunoTherapy of Cancer

vaccines and immunoinformatics approachesImmunotherapy and Immune Responses

Cited by 250

Intradermal Vaccinations With RNA Coding for TAA Generate CD8+ and CD4+ Immune Responses and Induce Clinical Benefit in Vaccinated Patients

Rittig, S. M., Haentschel, M., Weimer, K. J., Heine, A., Muller, M. R., Brugger, W., Horger, M. S., Maksimovic, O., Stenzl, A., Hoerr, I., et al. (2011) · Molecular Therapy

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 226

Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent

Probst, J., Weide, B., Scheel, B., Pichler, B. J., Hoerr, I., Rammensee, H.-G., & Pascolo, S. (2007) · Gene Therapy

RNA Interference and Gene DeliveryRNA and protein synthesis mechanisms

Cited by 206

The Peptide Vaccine of the Future

Nelde, A., Rammensee, H.-G., & Walz, J. S. (2021) · Molecular & Cellular Proteomics

Immunotherapy and Immune Responsesvaccines and immunoinformatics approaches

Cited by 205

Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy

Dutoit, V., Herold-Mende, C., Hilf, N., Schoor, O., Beckhove, P., Bucher, J., Dorsch, K., Flohr, S., Fritsche, J., Lewandrowski, P., et al. (2012) · Brain

Immunotherapy and Immune Responsesvaccines and immunoinformatics approaches

Cited by 201

Microbial peptides activate tumour-infiltrating lymphocytes in glioblastoma

Naghavian, R., Faigle, W., Oldrati, P., Wang, J., Toussaint, N. C., Qiu, Y., Medici, G., Wacker, M., Freudenmann, L. K., Bonté, P.-E., et al. (2023) · Nature

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 163

Polarization of immunity induced by direct injection of naked sequence-stabilized mRNA vaccines

Carralot, J.-P., Probst, J., Hoerr, I., Scheel, B., Teufel, R., Jung, G., Rammensee, H.-G., & Pascolo, S. (2004) · Cellular and Molecular Life Sciences CMLS

Immunotherapy and Immune ResponsesRNA Interference and Gene Delivery

Cited by 149

DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts

Goyal, A., Bauer, J., Hey, J., Papageorgiou, D. N., Stepanova, E., Daskalakis, M., Scheid, J., Dubbelaar, M., Klimovich, B., Schwarz, D., et al. (2023) · Nature Communications

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 102

Characterization of the ribonuclease activity on the skin surface

Probst, J., Brechtel, S., Scheel, B., Hoerr, I., Jung, G., Rammensee, H.-G., & Pascolo, S. (2006) · Genetic Vaccines and Therapy

RNA Interference and Gene DeliveryRNA Research and Splicing

Cited by 84

Autologous T cell therapy for PRAME+ advanced solid tumors in HLA-A*02+ patients: a phase 1 trial

Wermke, M., Araujo, D. M., Chatterjee, M., Tsimberidou, A. M., Holderried, T. A. W., Jazaeri, A. A., Reshef, R., Bokemeyer, C., Alsdorf, W., Wetzko, K., et al. (2025) · Nature Medicine

CAR-T cell therapy researchImmunotherapy and Immune Responses

Cited by 73

Promiscuous survivin peptide induces robust CD4+ T‐cell responses in the majority of vaccinated cancer patients

Widenmeyer, M., Griesemann, H., Stevanović, S., Feyerabend, S., Klein, R., Attig, S., Hennenlotter, J., Wernet, D., Kuprash, D. V., Sazykin, A. Y., et al. (2012) · International Journal of Cancer

Immunotherapy and Immune Responsesvaccines and immunoinformatics approaches

Cited by 70

A recombinant bispecific single‐chain antibody induces targeted, supra‐agonistic CD28‐stimulation and tumor cell killing

Grosse‐Hovest, L., Hartlapp, I., Marwan, W., Brem, G., Rammensee, H., & Jung, G. (2003) · European Journal of Immunology

Immunotherapy and Immune ResponsesMonoclonal and Polyclonal Antibodies Research

Cited by 62

Essential differences in ligand presentation and T cell epitope recognition among HLA molecules of the HLA‐B44 supertype

Hillen, N., Mester, G., Lemmel, C., Weinzierl, A. O., Müller, M., Wernet, D., Hennenlotter, J., Stenzl, A., Rammensee, H., & Stevanović, S. (2008) · European Journal of Immunology

vaccines and immunoinformatics approachesImmunotherapy and Immune Responses

Cited by 43

Insulin-mediated cortical activity in the slow frequency range is diminished in obese mice and promotes physical inactivity

Hennige, A. M., Sartorius, T., Lutz, S. Z., Tschritter, O., Preissl, H., Hopp, S., Fritsche, A., Rammensee, H.-G., Ruth, P., & Häring, H.-U. (2009) · Diabetologia

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 41

A bispecific single-chain antibody that mediates target cell-restricted, supra-agonistic CD28 stimulation and killing of lymphoma cells

Otz, T., Große-Hovest, L., Hofmann, M., Rammensee, H.-G., & Jung, G. (2009) · Leukemia

Monoclonal and Polyclonal Antibodies ResearchT-cell and B-cell Immunology

Cited by 38

Supraagonistic, bispecific single‐chain antibody purified from the serum of cloned, transgenic cows induces T‐cell‐mediated killing of glioblastoma cells in vitro and in vivo

Grosse‐Hovest, L., Wick, W., Minoia, R., Weller, M., Rammensee, H., Brem, G., & Jung, G. (2005) · International Journal of Cancer

Monoclonal and Polyclonal Antibodies ResearchImmunotherapy and Immune Responses

Cited by 23

Human peripheral blood monuclear cells transfected with messenger RNA stimulate antigen-specific cytotoxic T-lymphocytes in vitro

Teufel, R., Carralot, J.-P., Scheel, B., Probst, J., Walter, S., Jung, G., Hoerr, I., Rammensee, H.-G., & Pascolo, S. (2005) · Cellular and Molecular Life Sciences

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 22