Mann, Matthias

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

Cox, J., & Mann, M. (2008) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 14,855

Universal sample preparation method for proteome analysis

Wiśniewski, J. R., Zougman, A., Nagaraj, N., & Mann, M. (2009) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 8,352

Electrospray Ionization for Mass Spectrometry of Large Biomolecules

Fenn, J. B., Mann, M., Meng, C. K., Wong, S. F., & Whitehouse, C. M. (1989) · Science

Mass Spectrometry Techniques and ApplicationsElectrohydrodynamics and Fluid Dynamics

Cited by 7,634

Mass spectrometry-based proteomics

Aebersold, R., & Mann, M. (2003) · Nature

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 6,955

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

Ong, S.-E., Blagoev, B., Kratchmarova, I., Kristensen, D. B., Steen, H., Pandey, A., & Mann, M. (2002) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 5,574

Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ

Cox, J., Hein, M. Y., Luber, C. A., Paron, I., Nagaraj, N., & Mann, M. (2014) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 5,180

Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips

Rappsilber, J., Mann, M., & Ishihama, Y. (2007) · Nature Protocols

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 4,641

Lysine acetylation targets protein complexes and co-regulates major cellular functions

Choudhary, C., Kumar, C., Gnad, F., Nielsen, M. L., Rehman, M., Walther, T. C., Olsen, J. V., & Mann, M. (2009) · Science

Advanced Proteomics Techniques and ApplicationsGenomics and Chromatin Dynamics

Cited by 4,040

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., et al. (1996) · Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 3,046

A generic protein purification method for protein complex characterization and proteome exploration

Rigaut, G., Shevchenko, A., Rutz, B., Wilm, M., Mann, M., & Séraphin, B. (1999) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsBiotin and Related Studies

Cited by 2,707

Mass-spectrometric exploration of proteome structure and function

Aebersold, R., & Mann, M. (2016) · Nature

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 2,334

Exponentially Modified Protein Abundance Index (emPAI) for Estimation of Absolute Protein Amount in Proteomics by the Number of Sequenced Peptides per Protein

Ishihama, Y., Oda, Y., Tabata, T., Sato, T., Nagasu, T., Rappsilber, J., & Mann, M. (2005) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 2,055

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

Geiger, R., Rieckmann, J. C., Wolf, T., Basso, C., Feng, Y., Fuhrer, T., Kogadeeva, M., Picotti, P., Meissner, F., Mann, M., et al. (2016) · Cell

T-cell and B-cell ImmunologyAmino Acid Enzymes and Metabolism

Cited by 1,775

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

Kulak, N. A., Pichler, G., Paron, I., Nagaraj, N., & Mann, M. (2014) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 1,719

Mass spectrometry–based proteomics turns quantitative

Ong, S.-E., & Mann, M. (2005) · Nature Chemical Biology

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 1,572

The growing landscape of lysine acetylation links metabolism and cell signalling

Choudhary, C., Weinert, B. T., Nishida, Y., Verdin, E., & Mann, M. (2014) · Nature Reviews Molecular Cell Biology

Sirtuins and Resveratrol in MedicineAdvanced Proteomics Techniques and Applications

Cited by 1,324

Proteomic characterization of the human centrosome by protein correlation profiling

Andersen, J. S., Wilkinson, C. J., Mayor, T., Mortensen, P., Nigg, E. A., & Mann, M. (2003) · Nature

Advanced Proteomics Techniques and ApplicationsMicrotubule and mitosis dynamics

Cited by 1,319

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

Hein, M. Y., Hubner, N. C., Poser, I., Cox, J., Nagaraj, N., Toyoda, Y., Gak, I. A., Weisswange, I., Mansfeld, J., Buchholz, F., et al. (2015) · Cell

Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications

Cited by 1,270

Reverse Transcriptase Motifs in the Catalytic Subunit of Telomerase

Lingner, J., Hughes, T. R., Shevchenko, A., Mann, M., Lundblad, V., & Cech, T. R. (1997) · Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,269

Deep proteome and transcriptome mapping of a human cancer cell line

Nagaraj, N., Wisniewski, J. R., Geiger, T., Cox, J., Kircher, M., Kelso, J., Pääbo, S., & Mann, M. (2011) · Molecular Systems Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 979

Functional and quantitative proteomics using SILAC

Mann, M. (2006) · Nature Reviews Molecular Cell Biology

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 931

Revisiting biomarker discovery by plasma proteomics

Geyer, P. E., Holdt, L. M., Teupser, D., & Mann, M. (2017) · Molecular Systems Biology

Advanced Proteomics Techniques and ApplicationsAdvanced Biosensing Techniques and Applications

Cited by 917

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Mootha, V. K., Bunkenborg, J., Olsen, J. V., Hjerrild, M., Wisniewski, J. R., Stahl, E., Bolouri, M. S., Ray, H. N., Sihag, S., Kamal, M., et al. (2003) · Cell

Mitochondrial Function and PathologyBioinformatics and Genomic Networks

Cited by 889

Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

de Godoy, L. M. F., Olsen, J. V., Cox, J., Nielsen, M. L., Hubner, N. C., Fröhlich, F., Walther, T. C., & Mann, M. (2008) · Nature

Advanced Proteomics Techniques and ApplicationsFungal and yeast genetics research

Cited by 873