Mann, Matthias

Super-SILAC mix for quantitative proteomics of human tumor tissue

Geiger, T., Cox, J., Ostasiewicz, P., Wisniewski, J. R., & Mann, M. (2010) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 538

Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1

Schmidt, G., Sehr, P., Wilm, M., Selzer, J., Mann, M., & Aktories, K. (1997) · Nature

Protein Kinase Regulation and GTPase SignalingToxin Mechanisms and Immunotoxins

Cited by 530

Profiling the human intestinal environment under physiological conditions

Shalon, D., Culver, R. N., Grembi, J. A., Folz, J., Treit, P. V., Shi, H., Rosenberger, F. A., Dethlefsen, L., Meng, X., Yaffe, E., et al. (2023) · Nature

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 484

Mass spectrometry in high-throughput proteomics: ready for the big time

Nilsson, T., Mann, M., Aebersold, R., Yates, J. R., Bairoch, A., & Bergeron, J. J. M. (2010) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 470

A dual pressure linear ion trap orbitrap instrument with very high sequencing speed

Olsen, J. V., Schwartz, J. C., Griep-Raming, J., Nielsen, M. L., Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., et al. (2009) · Molecular & Cellular Proteomics

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 464

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation

Rigbolt, K. T. G., Prokhorova, T. A., Akimov, V., Henningsen, J., Johansen, P. T., Kratchmarova, I., Kassem, M., Mann, M., Olsen, J. V., & Blagoev, B. (2011) · Science Signaling

Pluripotent Stem Cells ResearchAdvanced Proteomics Techniques and Applications

Cited by 451

Precision proteomics: The case for high resolution and high mass accuracy

Mann, M., & Kelleher, N. L. (2008) · Proceedings of the National Academy of Sciences

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 450

Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions

Hubner, N. C., Bird, A. W., Cox, J., Splettstoesser, B., Bandilla, P., Poser, I., Hyman, A., & Mann, M. (2010) · Journal of Cell Biology

Advanced Proteomics Techniques and ApplicationsBiotin and Related Studies

Cited by 440

System-wide perturbation analysis with nearly complete coverage of the yeast proteome by single-shot ultra HPLC runs on a bench top Orbitrap

Nagaraj, N., Alexander Kulak, N., Cox, J., Neuhauser, N., Mayr, K., Hoerning, O., Vorm, O., & Mann, M. (2012) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 392

In-Vivo Quantitative Proteomics Reveals a Key Contribution of Post-Transcriptional Mechanisms to the Circadian Regulation of Liver Metabolism

Robles, M. S., Cox, J., & Mann, M. (2014) · PLoS Genetics

Circadian rhythm and melatoninAdvanced Proteomics Techniques and Applications

Cited by 383

Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming

Singhal, N., Graumann, J., Wu, G., Araúzo-Bravo, M. J., Han, D. W., Greber, B., Gentile, L., Mann, M., & Schöler, H. R. (2010) · Cell

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 378

Defining the transcriptome and proteome in three functionally different human cell lines

Lundberg, E., Fagerberg, L., Klevebring, D., Matic, I., Geiger, T., Cox, J., Älgenäs, C., Lundeberg, J., Mann, M., & Uhlen, M. (2010) · Molecular Systems Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 373

Ultra high resolution linear ion trap Orbitrap mass spectrometer (Orbitrap Elite) facilitates top down LC MS/MS and versatile peptide fragmentation modes

Michalski, A., Damoc, E., Lange, O., Denisov, E., Nolting, D., Müller, M., Viner, R., Schwartz, J., Remes, P., Belford, M., et al. (2012) · Molecular & Cellular Proteomics

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 373

Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins

Lam, Y. W., Lamond, A. I., Mann, M., & Andersen, J. S. (2007) · Current Biology

Nuclear Structure and FunctionRNA and protein synthesis mechanisms

Cited by 369

A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility

Bassik, M. C., Kampmann, M., Lebbink, R. J., Wang, S., Hein, M. Y., Poser, I., Weibezahn, J., Horlbeck, M. A., Chen, S., Mann, M., et al. (2013) · Cell

Toxin Mechanisms and ImmunotoxinsRNA Interference and Gene Delivery

Cited by 365

The Coming Age of Complete, Accurate, and Ubiquitous Proteomes

Mann, M., Kulak, N. A., Nagaraj, N., & Cox, J. (2013) · Molecular Cell

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 350

Plasma Proteome Profiling to detect and avoid sample‐related biases in biomarker studies

Geyer, P. E., Voytik, E., Treit, P. V., Doll, S., Kleinhempel, A., Niu, L., Müller, J. B., Buchholtz, M., Bader, J. M., Teupser, D., et al. (2019) · EMBO Molecular Medicine

Advanced Proteomics Techniques and ApplicationsAdvanced Biosensing Techniques and Applications

Cited by 348

Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging

Murgia, M., Toniolo, L., Nagaraj, N., Ciciliot, S., Vindigni, V., Schiaffino, S., Reggiani, C., & Mann, M. (2017) · Cell Reports

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 315

Regulation of G2/M events by Cdc25A through phosphorylation‐dependent modulation of its stability

Mailand, N., Podtelejnikov, A. V., Groth, A., Mann, M., Bartek, J., & Lukas, J. (2002) · The EMBO Journal

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 315

High Recovery FASP Applied to the Proteomic Analysis of Microdissected Formalin Fixed Paraffin Embedded Cancer Tissues Retrieves Known Colon Cancer Markers

Wiśniewski, J. R., Ostasiewicz, P., & Mann, M. (2011) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 290

Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease

Bader, J. M., Geyer, P. E., Müller, J. B., Strauss, M. T., Koch, M., Leypoldt, F., Koertvelyessy, P., Bittner, D., Schipke, C. G., Incesoy, E. I., et al. (2020) · Molecular Systems Biology

Alzheimer's disease research and treatmentsAdvanced Proteomics Techniques and Applications

Cited by 286

Systems-wide Proteomic Analysis in Mammalian Cells Reveals Conserved, Functional Protein Turnover

Cambridge, S. B., Gnad, F., Nguyen, C., Bermejo, J. L., Krüger, M., & Mann, M. (2011) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsUbiquitin and proteasome pathways

Cited by 277

Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and Proteome Quantitation of Mouse Embryonic Stem Cells to a Depth of 5,111 Proteins

Graumann, J., Hubner, N. C., Kim, J. B., Ko, K., Moser, M., Kumar, C., Cox, J., Schöler, H., & Mann, M. (2008) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 275

Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins

Neufeld-Cohen, A., Robles, M. S., Aviram, R., Manella, G., Adamovich, Y., Ladeuix, B., Nir, D., Rousso-Noori, L., Kuperman, Y., Golik, M., et al. (2016) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninMitochondrial Function and Pathology

Cited by 262