Nöthen, Markus M.

Follow-up of loci from the International Genomics of Alzheimer’s Disease Project identifies TRIP4 as a novel susceptibility gene

Ruiz, A., Heilmann, S., Becker, T., Hernández, I., Wagner, H., Thelen, M., Mauleón, A., Rosende-Roca, M., Bellenguez, C., Bis, J. C., et al. (2014) · Translational Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 97

Familial Occurrence of Systemic Mast Cell Activation Disease

Molderings, G. J., Haenisch, B., Bogdanow, M., Fimmers, R., & Nöthen, M. M. (2013) · PLoS ONE

Mast cells and histamineCongenital gastrointestinal and neural anomalies

Cited by 94

The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations

Schumacher, J., Laje, G., Jamra, R. A., Becker, T., Mühleisen, T. W., Vasilescu, C., Mattheisen, M., Herms, S., Hoffmann, P., Hillmer, A. M., et al. (2009) · Human Molecular Genetics

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 86

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

Vijayakrishnan, J., Studd, J., Broderick, P., Kinnersley, B., Holroyd, A., Law, P. J., Kumar, R., Allan, J. M., Harrison, C. J., Moorman, A. V., et al. (2018) · Nature Communications

Acute Lymphoblastic Leukemia researchGenetic Associations and Epidemiology

Cited by 84

Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder

Priebe, L., Degenhardt, F. A., Herms, S., Haenisch, B., Mattheisen, M., Nieratschker, V, Weingarten, M., Witt, S., Breuer, R., Paul, T., et al. (2012) · Molecular Psychiatry

Bipolar Disorder and TreatmentGenomic variations and chromosomal abnormalities

Cited by 84

Different familial transmission patterns in bipolar I disorder with onset before and after age 25

Grigoroiu‐Serbanescu, M., Martinez, M., Nöthen, M. M., Grinberg, M., Sima, D., Propping, P., Marinescu, E., & Hrestic, M. (2001) · American Journal of Medical Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 83

DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations

Sharma, A., Jamil, M. A., Nuesgen, N., Schreiner, F., Priebe, L., Hoffmann, P., Herns, S., Nöthen, M. M., Fröhlich, H., Oldenburg, J., et al. (2015) · Clinical Epigenetics

Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesEpigenetics and DNA Methylation

Cited by 81

Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder

Mühleisen, T. W., Mattheisen, M., Strohmaier, J., Degenhardt, F., Priebe, L., Schultz, C. C., Breuer, R., Meier, S., Hoffmann, P., Rivandeneira, F., et al. (2012) · Schizophrenia Research

Schizophrenia research and treatmentBipolar Disorder and Treatment

Cited by 80

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L., Schwantes-An, T.-H., Coon, H., Han, Y., Stephens, S. H., Sun, J., et al. (2012) · Archives of General Psychiatry

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 75

Association of a reproducible epigenetic risk profile for schizophrenia with brain methylation and function

Chen, J., Zang, Z., Braun, U., Schwarz, K., Harneit, A., Kremer, T., Ma, R., Schweiger, J., Moessnang, C., Geiger, L., et al. (2020) · JAMA Psychiatry

Epigenetics and DNA MethylationSchizophrenia research and treatment

Cited by 69

Longer telomere length in patients with schizophrenia

Nieratschker, V., Lahtinen, J., Meier, S., Strohmaier, J., Frank, J., Heinrich, A., Breuer, R., Witt, S. H., Nöthen, M. M., Rietschel, M., et al. (2013) · Schizophrenia Research

Schizophrenia research and treatmentTelomeres, Telomerase, and Senescence

Cited by 63

Common variation in NCAN, a risk factor for bipolar disorder and schizophrenia, influences local cortical folding in schizophrenia

Schultz, C. C., Mühleisen, T. W., Nenadic, I., Koch, K., Wagner, G., Schachtzabel, C., Siedek, F., Nöthen, M. M., Rietschel, M., Deufel, T., et al. (2014) · Psychological Medicine

Schizophrenia research and treatmentBipolar Disorder and Treatment

Cited by 60

Common Genetic Variants and Gene-Expression Changes Associated with Bipolar Disorder Are Over-Represented in Brain Signaling Pathway Genes

Pedroso, I., Lourdusamy, A., Rietschel, M., Nöthen, M. M., Cichon, S., McGuffin, P., Al-Chalabi, A., Barnes, M. R., & Breen, G. (2012) · Biological Psychiatry

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 59

Association analysis of the dopamine D2receptor gene in Tourette's syndrome using the haplotype relative risk method

Nöthen, M. M., Hebebrand, J., Knapp, M., Hebebrand, K., Camps, A., von Gontard, A., Wettke‐Schäfer, R., Lisch, S., Cichon, S., Poustka, F., et al. (1994) · American Journal of Medical Genetics

Obsessive-Compulsive Spectrum DisordersGenetic Associations and Epidemiology

Cited by 52

Elucidation of the genetic causes of bicuspid aortic valve disease

Gehlen, J., Stundl, A., Debiec, R., Fontana, F., Krane, M., Sharipova, D., Nelson, C. P., Al-Kassou, B., Giel, A.-S., Sinning, J.-M., et al. (2023) · Cardiovascular Research

Cardiac Valve Diseases and TreatmentsCongenital heart defects research

Cited by 51

SUCLG2 identified as both a determinator of CSF Aβ1–42 levels and an attenuator of cognitive decline in Alzheimer's disease

Ramirez, A., van der Flier, W. M., Herold, C., Ramonet, D., Heilmann, S., Lewczuk, P., Popp, J., Lacour, A., Drichel, D., Louwersheimer, E., et al. (2014) · Human Molecular Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 49

Systemic mast cell activation disease: the role of molecular genetic alterations in pathogenesis, heritability and diagnostics

Haenisch, B., Nöthen, M. M., & Molderings, G. J. (2012) · Immunology

Mast cells and histamineImmunodeficiency and Autoimmune Disorders

Cited by 48

Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression

Mucha, S., Baurecht, H., Novak, N., Rodríguez, E., Bej, S., Mayr, G., Emmert, H., Stölzl, D., Gerdes, S., Jung, E. S., et al. (2020) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesGenetic Associations and Epidemiology

Cited by 48

Epigenome-wide association study of alcohol use disorder in five brain regions

Zillich, L., Frank, J., Streit, F., Friske, M. M., Foo, J. C., Sirignano, L., Heilmann-Heimbach, S., Dukal, H., Degenhardt, F., Hoffmann, P., et al. (2022) · Neuropsychopharmacology

Epigenetics and DNA MethylationSubstance Abuse Treatment and Outcomes

Cited by 36

Acute alcohol withdrawal and recovery in men lead to profound changes in DNA methylation profiles: a longitudinal clinical study

Witt, S. H., Frank, J., Frischknecht, U., Treutlein, J., Streit, F., Foo, J. C., Sirignano, L., Dukal, H., Degenhardt, F., Koopmann, A., et al. (2020) · Addiction

Epigenetics and DNA MethylationAlcohol Consumption and Health Effects

Cited by 35

Ventral Striatal–Hippocampus Coupling During Reward Processing as a Stratification Biomarker for Psychotic Disorders

Schwarz, K., Moessnang, C., Schweiger, J. I., Harneit, A., Schneider, M., Chen, J., Cao, H., Schwarz, E., Witt, S. H., Rietschel, M., et al. (2022) · Biological Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 18

Association between neuropeptide Y receptor Y2 promoter variant rs6857715 and major depressive disorder

Treutlein, J., Strohmaier, J., Frank, J., Witt, S. H., Rietschel, L., Forstner, A. J., Lang, M., Degenhardt, F., Dukal, H., Herms, S., et al. (2017) · Psychiatric Genetics

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 18

Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction

Small, A. M., Yang, T.-Y., Itoh, S., Thériault, S., Dufresne, L., Kurosawa, R., Komuro, I., Matsuda, K., Vy, H. M. T., Farber-Eger, E. H., et al. (2026) · Nature Genetics

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 18

Mutational profiling in the peripheral blood leukocytes of patients with systemic mast cell activation syndrome using next-generation sequencing

Altmüller, J., Haenisch, B., Kawalia, A., Menzen, M., Nöthen, M. M., Fier, H., & Molderings, G. J. (2017) · Immunogenetics

Mast cells and histamineCongenital gastrointestinal and neural anomalies

Cited by 14