Boulton, Simon J.

Poly(ADP-ribose)–Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1

Ahel, D., Hořejší, Z., Wiechens, N., Polo, S. E., Garcia-Wilson, E., Ahel, I., Flynn, H., Skehel, M., West, S. C., Jackson, S. P., et al. (2009) · Science

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 588

Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place

Kotsantis, P., Petermann, E., & Boulton, S. J. (2018) · Cancer Discovery

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 416

RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination

Barber, L. J., Youds, J. L., Ward, J. D., McIlwraith, M. J., O'Neil, N. J., Petalcorin, M. I. R., Martin, J. S., Collis, S. J., Cantor, S. B., Auclair, M., et al. (2008) · Cell

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 369

BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair

Chapman, J. R., Sossick, A. J., Boulton, S. J., & Jackson, S. P. (2012) · Journal of Cell Science

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 327

Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN

Arnoult, N., Correia, A., Ma, J., Merlo, A., Garcia-Gomez, S., Maric, M., Tognetti, M., Benner, C. W., Boulton, S. J., Saghatelian, A., et al. (2017) · Nature

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 299

FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts

London, T. B. C., Barber, L. J., Mosedale, G., Kelly, G. P., Balasubramanian, S., Hickson, I. D., Boulton, S. J., & Hiom, K. (2008) · Journal of Biological Chemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 252

BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks

Higgs, M. R., Reynolds, J. J., Winczura, A., Blackford, A. N., Borel, V., Miller, E. S., Zlatanou, A., Nieminuszczy, J., Ryan, E. L., Davies, N. J., et al. (2015) · Molecular Cell

DNA Repair MechanismsFungal and yeast genetics research

Cited by 194

Genomic landscape of oxidative DNA damage and repair reveals regioselective protection from mutagenesis

Poetsch, A. R., Boulton, S. J., & Luscombe, N. M. (2018) · Genome Biology

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

Cited by 132

The end protection problem—an unexpected twist in the tail

Ruis, P., & Boulton, S. J. (2021) · Genes & Development

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 57

The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining

Fleury, H., MacEachern, M. K., Stiefel, C. M., Anand, R., Sempeck, C., Nebenfuehr, B., Maurer-Alcalá, K., Ball, K., Proctor, B., Belan, O., et al. (2023) · Molecular Cell

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 52