Gitelman, Stephen E.

Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

Herold, K. C., Hagopian, W., Auger, J. A., Poumian-Ruiz, E., Taylor, L., Donaldson, D., Gitelman, S. E., Harlan, D. M., Xu, D., Zivin, R. A., et al. (2002) · New England Journal of Medicine

Diabetes and associated disordersDiabetes Management and Research

Cited by 1,222

An anti-CD3 antibody, teplizumab, in relatives at risk for type 1 diabetes

Herold, K. C., Bundy, B. N., Long, S. A., Bluestone, J. A., DiMeglio, L. A., Dufort, M. J., Gitelman, S. E., Gottlieb, P. A., Krischer, J. P., Linsley, P. S., et al. (2019) · New England Journal of Medicine

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 1,189

Rituximab, B-lymphocyte depletion, and preservation of beta-cell function

Pescovitz, M. D., Greenbaum, C. J., Krause-Steinrauf, H., Becker, D. J., Gitelman, S. E., Goland, R., Gottlieb, P. A., Marks, J. B., McGee, P. F., Moran, A. M., et al. (2009) · New England Journal of Medicine

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 1,093

Type 1 diabetes immunotherapy using polyclonal regulatory T cells

Bluestone, J. A., Buckner, J. H., Fitch, M., Gitelman, S. E., Gupta, S., Hellerstein, M. K., Herold, K. C., Lares, A., Lee, M. R., Li, K., et al. (2015) · Science Translational Medicine

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 1,033

Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial

Orban, T., Bundy, B., Becker, D. J., DiMeglio, L. A., Gitelman, S. E., Goland, R., Gottlieb, P. A., Greenbaum, C. J., Marks, J. B., Monzavi, R., et al. (2011) · The Lancet

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 612

Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals

Sims, E. K., Bundy, B. N., Stier, K., Serti, E., Lim, N., Long, S. A., Geyer, S. M., Moran, A., Greenbaum, C. J., Evans-Molina, C., et al. (2021) · Science Translational Medicine

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 377

Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial

Wherrett, D. K., Bundy, B., Becker, D. J., DiMeglio, L. A., Gitelman, S. E., Goland, R., Gottlieb, P. A., Greenbaum, C. J., Herold, K. C., Marks, J. B., et al. (2011) · The Lancet

Diabetes and associated disordersDiabetes Management and Research

Cited by 371

Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes

Battaglia, M., Ahmed, S., Anderson, M. S., Atkinson, M. A., Becker, D., Bingley, P. J., Bosi, E., Brusko, T. M., DiMeglio, L. A., Evans-Molina, C., et al. (2020) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 351

Fall in C-Peptide During First 2 Years From Diagnosis

Greenbaum, C. J., Beam, C. A., Boulware, D., Gitelman, S. E., Gottlieb, P. A., Herold, K. C., Lachin, J. M., McGee, P., Palmer, J. P., Pescovitz, M. D., et al. (2012) · Diabetes

Diabetes and associated disordersDiabetes Management and Research

Cited by 319

Teplizumab and β-cell function in newly diagnosed type 1 diabetes

Ramos, E. L., Dayan, C. M., Chatenoud, L., Sumnik, Z., Simmons, K. M., Szypowska, A., Gitelman, S. E., Knecht, L. A., Niemoeller, E., Tian, W., et al. (2023) · New England Journal of Medicine

Diabetes and associated disordersDiabetes Management and Research

Cited by 273

Treatment of patients with new onset type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years

Herold, K. C., Gitelman, S., Greenbaum, C., Puck, J., Hagopian, W., Gottlieb, P., Sayre, P., Bianchine, P., Wong, E., Seyfert-Margolis, V., et al. (2009) · Clinical Immunology

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 219

Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes

Haller, M. J., Gitelman, S. E., Gottlieb, P. A., Michels, A. W., Rosenthal, S. M., Shuster, J. J., Zou, B., Brusko, T. M., Hulme, M. A., Wasserfall, C. H., et al. (2015) · Journal of Clinical Investigation

Diabetes and associated disordersPancreatic function and diabetes

Cited by 167

Transcript encoded on the opposite strand of the human steroid 21-hydroxylase/complement component/C4 gene locus

Morel, Y., Bristow, J., Gitelman, S. E., & Miller, W. L. (1989) · Proceedings of the National Academy of Sciences

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 158

Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial

Russell, W. E., Bundy, B. N., Anderson, M. S., Cooney, L. A., Gitelman, S. E., Goland, R. S., Gottlieb, P. A., Greenbaum, C. J., Haller, M. J., Krischer, J. P., et al. (2023) · Diabetes Care

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 108

Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus

Gitelman, S. E., Bristow, J., & Miller, W. L. (1992) · Molecular and Cellular Biology

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 106

Abundant adrenal-specific transcription of the human P450c21A “pseudogene.”

Bristow, J., Gitelman, S. E., Tee, M. K., Staels, B., & Miller, W. L. (1993) · Journal of Biological Chemistry

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 84

Antithymocyte globulin plus G-CSF combination therapy leads to sustained immunomodulatory and metabolic effects in a subset of responders with established type 1 diabetes

Haller, M. J., Gitelman, S. E., Gottlieb, P. A., Michels, A. W., Perry, D. J., Schultz, A. R., Hulme, M. A., Shuster, J. J., Zou, B., Wasserfall, C. H., et al. (2016) · Diabetes

Diabetes and associated disordersPancreatic function and diabetes

Cited by 70

Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis

Takele, W. W., Vesco, K. K., Josefson, J., Redman, L. M., Hannah, W., Bonham, M. P., Chen, M., Chivers, S. C., Fawcett, A. J., Grieger, J. A., et al. (2024) · Communications Medicine

Gestational Diabetes Research and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 55

A promoter within intron 35 of the human C4A gene initiates abundant adrenal-specific transcription of a 1 kb RNA: location of a cryptic CYP21 promoter element?

Tee, M. K., Babalola, G. O., Aza-Blanc, P., Speek, M., Gitelman, S. E., & Miller, W. L. (1995) · Human Molecular Genetics

Genomics and Chromatin DynamicsComplement system in diseases

Cited by 47

Real-time continuous glucose monitoring in adolescents and young adults with type 2 diabetes can improve quality of life

Chesser, H., Srinivasan, S., Puckett, C., Gitelman, S. E., & Wong, J. C. (2024) · Journal of Diabetes Science and Technology

Diabetes Management and ResearchDiabetes Management and Education

Cited by 40

The Role of Age and Excess Body Mass Index in Progression to Type 1 Diabetes in At-Risk Adults

Ferrara, C. T., Geyer, S. M., Evans-Molina, C., Libman, I. M., Becker, D. J., Wentworth, J. M., Moran, A., Gitelman, S. E., Redondo, M. J., & Type 1 Diabetes TrialNet Study Group (2017) · The Journal of Clinical Endocrinology & Metabolism

Diabetes and associated disordersDiabetes Management and Research

Cited by 33

Pediatric Endocrine Society Statement on Considerations for Use of Teplizumab (Tzield™) in Clinical Practice

Mehta, S., Ryabets-Lienhard, A., Patel, N., Breidbart, E., Libman, I., Haller, M. J., Simmons, K. M., Sims, E. K., DiMeglio, L. A., Gitelman, S. E., et al. (2024) · Hormone Research in Paediatrics

Diabetes and associated disordersDiabetes Management and Research

Cited by 17