Simó, Rafael

Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): a randomised controlled trial

on behalf of the Liraglutide Effect and Action in Diabetes 5 (LEAD-5) met+SU Study Group, Russell-Jones, D., Vaag, A., Schmitz, O., Sethi, B. K., Lalic, N., Antic, S., Zdravkovic, M., Ravn, G. M., & Simó, R. (2009) · Diabetologia

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 835

Screening for diabetic retinopathy: new perspectives and challenges

Vujosevic, S., Aldington, S. J., Silva, P., Hernández, C., Scanlon, P., Peto, T., & Simó, R. (2020) · The Lancet Diabetes & Endocrinology

Retinal Imaging and AnalysisRetinal Diseases and Treatments

Cited by 671

Effects of sotagliflozin added to insulin in patients with type 1 diabetes

Garg, S. K., Henry, R. R., Banks, P., Buse, J. B., Davies, M. J., Fulcher, G. R., Pozzilli, P., Gesty-Palmer, D., Lapuerta, P., Simó, R., et al. (2017) · New England Journal of Medicine

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 417

Novel insights in SHBG regulation and clinical implications

Simó, R., Sáez-López, C., Barbosa-Desongles, A., Hernández, C., & Selva, D. M. (2015) · Trends in Endocrinology & Metabolism

Hormonal and reproductive studiesEstrogen and related hormone effects

Cited by 335

Semaglutide, reduction in glycated haemoglobin and the risk of diabetic retinopathy

Vilsbøll, T., Bain, S. C., Leiter, L. A., Lingvay, I., Matthews, D., Simó, R., Helmark, I. C., Wijayasinghe, N., & Larsen, M. (2018) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementRetinal Diseases and Treatments

Cited by 318

Topical Administration of GLP-1 Receptor Agonists Prevents Retinal Neurodegeneration in Experimental Diabetes

Hernández, C., Bogdanov, P., Corraliza, L., García-Ramírez, M., Solà-Adell, C., Arranz, J. A., Arroba, A. I., Valverde, A. M., & Simó, R. (2016) · Diabetes

Retinal Diseases and TreatmentsDiabetes Treatment and Management

Cited by 267

Integrated image-based deep learning and language models for primary diabetes care

Li, J., Guan, Z., Wang, J., Cheung, C. Y., Zheng, Y., Lim, L.-L., Lim, C. C., Ruamviboonsuk, P., Raman, R., Corsino, L., et al. (2024) · Nature Medicine

Artificial Intelligence in Healthcare and EducationMachine Learning in Healthcare

Cited by 250

Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: A randomised, double-blind, placebo-controlled, phase 2 trial

von Herrath, M., Bain, S. C., Bode, B., Clausen, J. O., Coppieters, K., Gaysina, L., Gumprecht, J., Hansen, T. K., Mathieu, C., Morales, C., et al. (2021) · The Lancet Diabetes & Endocrinology

Diabetes and associated disordersPancreatic function and diabetes

Cited by 186

Association between diabetic eye disease and other complications of diabetes: Implications for care. A systematic review

Pearce, I., Simó, R., Lövestam‐Adrian, M., Wong, D. T., & Evans, M. (2019) · Diabetes, Obesity and Metabolism

Retinal Diseases and TreatmentsDiabetes Management and Research

Cited by 180

Study of the potential association of adipose tissue GLP-1 receptor with obesity and insulin resistance

Vendrell, J., El Bekay, R., Peral, B., García-Fuentes, E., Megia, A., Macias-Gonzalez, M., Real, J. F., Jimenez-Gomez, Y., Escoté, X., Pachón, G., et al. (2011) · Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesDiabetes Treatment and Management

Cited by 173

Relationship between Central Obesity and the incidence of Cognitive Impairment and Dementia from Cohort Studies Involving 5,060,687 Participants

Tang, X., Zhao, W., Lu, M., Zhang, X., Zhang, P., Xin, Z., Sun, R., Tian, W., Cardoso, M. A., Yang, J., et al. (2021) · Neuroscience & Biobehavioral Reviews

Dementia and Cognitive Impairment ResearchMenopause: Health Impacts and Treatments

Cited by 154

The Association Between Diabetes Mellitus and Risk of Sarcopenia: Accumulated Evidences From Observational Studies

Qiao, Y.-S., Chai, Y.-H., Gong, H.-J., Zhuldyz, Z., Stehouwer, C. D. A., Zhou, J.-B., & Simó, R. (2021) · Frontiers in Endocrinology

Nutrition and Health in AgingDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 132

Study of glucose tolerance in consecutive patients harbouring incidental adrenal tumours

Fernández‐Real, J. M., Ricart Engel, W., Simó, R., Salinas, I., Webb, S. M., & and the Study Group of Incidental Adrenal Adenoma (1998) · Clinical Endocrinology

Adrenal and Paraganglionic TumorsAdrenal Hormones and Disorders

Cited by 109

Artificial intelligence for diabetes care: current and future prospects

Sheng, B., Pushpanathan, K., Guan, Z., Lim, Q. H., Lim, Z. W., Yew, S. M. E., Goh, J. H. L., Bee, Y. M., Sabanayagam, C., Sevdalis, N., et al. (2024) · The Lancet Diabetes & Endocrinology

Artificial Intelligence in Healthcare and EducationDiabetes Management and Research

Cited by 106

A compartmentalized microfluidic chip with crisscross microgrooves and electrophysiological electrodes for modeling the blood–retinal barrier

Yeste, J., García-Ramírez, M., Illa, X., Guimerà, A., Hernández, C., Simó, R., & Villa, R. (2018) · Lab on a Chip

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 89

GLP-1R as a Target for the Treatment of Diabetic Retinopathy: Friend or Foe?

Simó, R., & Hernández, C. (2017) · Diabetes

Diabetes Treatment and ManagementRetinal Diseases and Treatments

Cited by 86

Sex Hormone-Binding Globulin Reduction in Metabolic Disorders May Play a Role in NAFLD Development

Sáez‐López, C., Barbosa-Desongles, A., Hernández, C., Dyer, R., Innis, S. M., Simó, R., & Selva, D. M. (2017) · EndocrinologyJN

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 71

Eating disorders are frequent among type 2 diabetic patients and are associated with worse metabolic and psychological outcomes: results from a cross-sectional study in primary and secondary care settings

Nicolau, J., Simó, R., Sanchís, P., Ayala, L., Fortuny, R., Zubillaga, I., & Masmiquel, L. (2015) · Acta Diabetologica

Eating Disorders and BehaviorsNutrition, Health and Food Behavior

Cited by 60

Long-term changes in cardiovascular risk markers during administration of exenatide twice daily or glimepiride: results from the European exenatide study

Simó, R., Guerci, B., Schernthaner, G., Gallwitz, B., Rosas-Guzmàn, J., Dotta, F., Festa, A., Zhou, M., & Kiljański, J. (2015) · Cardiovascular Diabetology

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 47

Sex hormone-binding globulin overexpression protects against high-fat diet-induced obesity in transgenic male mice

Saez-Lopez, C., Villena, J. A., Simó, R., & Selva, D. M. (2020) · The Journal of Nutritional Biochemistry

Adipokines, Inflammation, and Metabolic DiseasesRegulation of Appetite and Obesity

Cited by 38

Efficacy and safety of once-daily insulin degludec/insulin aspart versus insulin glargine (u100) for 52 weeks in insulin-naïve patients with type 2 diabetes: A randomized controlled trial

Kumar, A., Franek, E., Wise, J., Niemeyer, M., Mersebach, H., & Simó, R. (2016) · PLOS ONE

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 38

Clinical significance of RET/PTC and p53 protein expression in sporadic papillary thyroid carcinoma

Zafon, C., Obiols, G., Castellví, J., Tallada, N., Baena, J. A., Simó, R., & Mesa, J. (2007) · Histopathology

Thyroid Cancer Diagnosis and TreatmentThyroid and Parathyroid Surgery

Cited by 31

Calorie restriction prevents diet‐induced insulin resistance independently of PGC‐1‐driven mitochondrial biogenesis in white adipose tissue

Pardo, R., Vilà, M., Cervela, L., de Marco, M., Gama-Pérez, P., González-Franquesa, A., Statuto, L., Vilallonga, R., Simó, R., Garcia-Roves, P. M., et al. (2019) · The FASEB Journal

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 27

Switching from treatment with sensor augmented pump to hybrid closed loop system in type 1 diabetes: impact on glycemic control and neuropsychological tests in the real world

Amigó, J., Ortiz-Zúñiga, Á., de Urbina, A. M. O., Sánchez, M., Dos-Santos, M., Abad, M., Cuadra, F., Simó, R., Hernández, C., & Simó-Servat, O. (2023) · Diabetes Research and Clinical Practice

Diabetes Management and ResearchDiabetes Management and Education

Cited by 15