Chen, Wei

Global quantification of mammalian gene expression control

Schwanhäusser, B., Busse, D., Li, N., Dittmar, G., Schuchhardt, J., Wolf, J., Chen, W., & Selbach, M. (2011) · Nature

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 6,566

miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades

Friedländer, M. R., Mackowiak, S. D., Li, N., Chen, W., & Rajewsky, N. (2012) · Nucleic Acids Research

MicroRNA in disease regulationGenomics and Phylogenetic Studies

Cited by 3,207

Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity

You, X., Vlatkovic, I., Babic, A., Will, T., Epstein, I., Tushev, G., Akbalik, G., Wang, M., Glock, C., Quedenau, C., et al. (2015) · Nature Neuroscience

Circular RNAs in diseasesRNA Research and Splicing

Cited by 1,149

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

Najmabadi, H., Hu, H., Garshasbi, M., Zemojtel, T., Abedini, S. S., Chen, W., Hosseini, M., Behjati, F., Haas, S., Jamali, P., et al. (2011) · Nature

Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases

Cited by 965

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

Peleg, S., Sananbenesi, F., Zovoilis, A., Burkhardt, S., Bahari-Javan, S., Agis-Balboa, R. C., Cota, P., Wittnam, J. L., Gogol-Doering, A., Opitz, L., et al. (2010) · Science

Memory and Neural MechanismsGenomics and Chromatin Dynamics

Cited by 951

Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells

Marguerat, S., Schmidt, A., Codlin, S., Chen, W., Aebersold, R., & Bähler, J. (2012) · Cell

Gene Regulatory Network AnalysisAdvanced Proteomics Techniques and Applications

Cited by 571

Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia

Kirov, G., Gumus, D., Chen, W., Norton, N., Georgieva, L., Sari, M., O'Donovan, M. C., Erdogan, F., Owen, M. J., Ropers, H.-H., et al. (2007) · Human Molecular Genetics

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 377

Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and disease

Hu, L., Chen, W., Qian, A., & Li, Y.-P. (2024) · Bone Research

Wnt/β-catenin signaling in development and cancerBone Metabolism and Diseases

Cited by 359

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain

Somel, M., Guo, S., Fu, N., Yan, Z., Hu, H. Y., Xu, Y., Yuan, Y., Ning, Z., Hu, Y., Menzel, C., et al. (2010) · Genome Research

Genetics, Aging, and Longevity in Model OrganismsMicroRNA in disease regulation

Cited by 297

Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques

Liu, X., Somel, M., Tang, L., Yan, Z., Jiang, X., Guo, S., Yuan, Y., He, L., Oleksiak, A., Zhang, Y., et al. (2012) · Genome Research

Genetics and Neurodevelopmental DisordersNeurogenesis and neuroplasticity mechanisms

Cited by 251

MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates

Somel, M., Liu, X., Tang, L., Yan, Z., Hu, H., Guo, S., Jiang, X., Zhang, X., Xu, G., Xie, G., et al. (2011) · PLoS Biology

MicroRNA in disease regulationDevelopmental Biology and Gene Regulation

Cited by 232

Widespread splicing changes in human brain development and aging

Mazin, P., Xiong, J., Liu, X., Yan, Z., Zhang, X., Li, M., He, L., Somel, M., Yuan, Y., Phoebe Chen, Y., et al. (2013) · Molecular Systems Biology

RNA Research and SplicingRNA regulation and disease

Cited by 216

Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states

Pham, T.-H., Benner, C., Lichtinger, M., Schwarzfischer, L., Hu, Y., Andreesen, R., Chen, W., & Rehli, M. (2012) · Blood

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 143

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Leddin, M., Perrod, C., Hoogenkamp, M., Ghani, S., Assi, S., Heinz, S., Wilson, N. K., Follows, G., Schönheit, J., Vockentanz, L., et al. (2011) · Blood

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 131

MicroRNA Expression and Regulation in Human, Chimpanzee, and Macaque Brains

Hu, H. Y., Guo, S., Xi, J., Yan, Z., Fu, N., Zhang, X., Menzel, C., Liang, H., Yang, H., Zhao, M., et al. (2011) · PLoS Genetics

MicroRNA in disease regulationChromosomal and Genetic Variations

Cited by 130

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control

Yang, J.-Y., Deng, X.-Y., Li, Y.-S., Ma, X.-C., Feng, J.-X., Yu, B., Chen, Y., Luo, Y.-L., Wang, X., Chen, M.-L., et al. (2018) · Nature Communications

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 124

Pervasive isoform‐specific translational regulation via alternative transcription start sites in mammals

Wang, X., Hou, J., Quedenau, C., & Chen, W. (2016) · Molecular Systems Biology

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 90

Identification of PENDRIN (SLC26A4) Mutations in Patients With Congenital Hypothyroidism and “Apparent” Thyroid Dysgenesis

Kühnen, P., Turan, S., Fröhler, S., Güran, T., Abali, S., Biebermann, H., Bereket, A., Grüters, A., Chen, W., & Krude, H. (2014) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsHead and Neck Anomalies

Cited by 63

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

Bogdanow, B., Wang, X., Eichelbaum, K., Sadewasser, A., Husic, I., Paki, K., Budt, M., Hergeselle, M., Vetter, B., Hou, J., et al. (2019) · Nature Communications

Influenza Virus Research StudiesRNA Research and Splicing

Cited by 56

Distinct populations of highly potent TAU seed conformers in rapidly progressing Alzheimer’s disease

Kim, C., Haldiman, T., Kang, S.-G., Hromadkova, L., Han, Z. Z., Chen, W., Lissemore, F., Lerner, A., de Silva, R., Cohen, M. L., et al. (2022) · Science Translational Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 55

Mutation screening in 86 known X-linked mental retardation genes by droplet-based multiplex PCR and massive parallel sequencing

Hu, H., Wrogemann, K., Kalscheuer, V., Tzschach, A., Richard, H., Haas, S. A., Menzel, C., Bienek, M., Froyen, G., Raynaud, M., et al. (2009) · The HUGO Journal

Genomics and Rare DiseasesGenetics and Neurodevelopmental Disorders

Cited by 49

DeeReCT-APA: Prediction of Alternative Polyadenylation Site Usage Through Deep Learning

Li, Z., Li, Y., Zhang, B., Li, Y., Long, Y., Zhou, J., Zou, X., Zhang, M., Hu, Y., Chen, W., et al. (2022) · Genomics, Proteomics & Bioinformatics

RNA Research and SplicingGenomics and Phylogenetic Studies

Cited by 37