Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

Heinz, S., Benner, C., Spann, N., Bertolino, E., Lin, Y. C., Laslo, P., Cheng, J. X., Murre, C., Singh, H., & Glass, C. K. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.05.004 · Cited by 13,382 · see citing works

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

Heintzman, N. D., Stuart, R. K., Hon, G., Fu, Y., Ching, C. W., Hawkins, R. D., Barrera, L. O., Van Calcar, S., Qu, C., Ching, K. A., et al. (2007) · Nature Genetics · doi:10.1038/ng1966 · Cited by 3,398 · see citing works

Mapping short DNA sequencing reads and calling variants using mapping quality scores

Li, H., Ruan, J., & Durbin, R. (2008) · Genome Research · doi:10.1101/gr.078212.108 · Cited by 2,638 · see citing works

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

Akashi, K., Traver, D., Miyamoto, T., & Weissman, I. L. (2000) · Nature · doi:10.1038/35004599 · Cited by 2,617 · see citing works

Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages

Scott, E. W., Simon, M. C., Anastasi, J., & Singh, H. (1994) · Science · doi:10.1126/science.8079170 · Cited by 1,532 · see citing works

NUCLEASE HYPERSENSITIVE SITES IN CHROMATIN

Gross, D. S., & Garrard, W. T. (1988) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.57.070188.001111 · Cited by 1,233 · see citing works

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

McKercher, S. R., Torbett, B. E., Anderson, K. L., Henkel, G. W., Vestal, D. J., Baribault, H., Klemsz, M., Feeney, A. J., Wu, G. E., Paige, C. J., et al. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00949.x · Cited by 1,130 · see citing works

Stepwise reprogramming of B cells into macrophages.

Xie, H.-F., Ye, M., Feng, R., & Graf, T. (2004) · Cell · doi:10.1016/s0092-8674(04)00419-2 · Cited by 1,030 · see citing works

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., & Maki, R. A. (1990) · Cell · doi:10.1016/0092-8674(90)90219-5 · Cited by 954 · see citing works

Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages

Ghisletti, S., Barozzi, I., Mietton, F., Polletti, S., De Santa, F., Venturini, E., Gregory, L., Lonie, L., Chew, A., Wei, C.-L., et al. (2010) · Immunity · doi:10.1016/j.immuni.2010.02.008 · Cited by 666 · see citing works

Multilineage Transcriptional Priming and Determination of Alternate Hematopoietic Cell Fates

Laslo, P., Spooner, C. J., Warmflash, A., Lancki, D. W., Lee, H.-J., Sciammas, R., Gantner, B. N., Dinner, A. R., & Singh, H. (2006) · Cell · doi:10.1016/j.cell.2006.06.052 · Cited by 632 · see citing works

Genomic views of distant-acting enhancers

Visel, A., Rubin, E. M., & Pennacchio, L. A. (2009) · Nature · doi:10.1038/nature08451 · Cited by 610 · see citing works

Transcription factors in myeloid development: balancing differentiation with transformation

Rosenbauer, F., & Tenen, D. G. (2007) · Nature Reviews Immunology · doi:10.1038/nri2024 · Cited by 606 · cited 1× · see citing works

Targeted Deletion of a High-Affinity GATA-binding Site in the GATA-1 Promoter Leads to Selective Loss of the Eosinophil Lineage In Vivo

Yu, C., Cantor, A. B., Yang, H., Browne, C., Wells, R. A., Fujiwara, Y., & Orkin, S. H. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20020656 · Cited by 600 · cited 1× · see citing works

Diversification of haematopoietic stem cells to specific lineages

Orkin, S. H. (2000) · Nature Reviews Genetics · doi:10.1038/35049577 · Cited by 564 · see citing works

Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

Rosenbauer, F., Wagner, K., Kutok, J. L., Iwasaki, H., Le Beau, M. M., Okuno, Y., Akashi, K., Fiering, S., & Tenen, D. G. (2004) · Nature Genetics · doi:10.1038/ng1361 · Cited by 506 · see citing works

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

Lin, Y. C., Jhunjhunwala, S., Benner, C. W., Heinz, S., Welinder, E., Månsson, R., Sigvardsson, M., Hagman, J. R., Espinoza, C. A., Dutkowski, J., et al. (2010) · Nature Immunology · doi:10.1038/ni.1891 · Cited by 502 · see citing works

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction

Bröske, A.-M., Vockentanz, L., Kharazi, S., Huska, M. R., Mancini, E., Scheller, M., Kuhl, C., Enns, A., Prinz, M., Jaenisch, R., et al. (2009) · Nature Genetics · doi:10.1038/ng.463 · Cited by 478 · see citing works

STAMP: a web tool for exploring DNA-binding motif similarities

Mahony, S., & Benos, P. V. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm272 · Cited by 469 · see citing works

Spi-1 is a putative oncogene in virally induced murine erythroleukaemias

Moreau-Gachelin, F., Tavitian, A., & Tambourin, P. (1988) · Nature · doi:10.1038/331277a0 · Cited by 447 · see citing works

The landscape of histone modifications across 1% of the human genome in five human cell linesPreprint

Andrews, R., Beare, D., Flicek, P., Bruce, A., Carter, N., Clelland, G., Wilcox, S., Beare, D. M., Fowler, J. C., Dovey, O., et al. (2007) · Genome Research · doi:10.1101/gr.5704207 · Cited by 441 · see citing works

Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation

Iwasaki, H., Somoza, C., Shigematsu, H., Duprez, E. A., Iwasaki-Arai, J., Mizuno, S.-I., Arinobu, Y., Geary, K., Zhang, P., Dayaram, T., et al. (2005) · Blood · doi:10.1182/blood-2005-03-0860 · Cited by 433 · see citing works

Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPα ratio and granulocyte colony-stimulating factor

Dahl, R., Walsh, J. C., Lancki, D., Laslo, P., Iyer, S. R., Singh, H., & Simon, M. C. (2003) · Nature Immunology · doi:10.1038/ni973 · Cited by 380 · see citing works

Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors

Nutt, S. L., Metcalf, D., D'Amico, A., Polli, M., & Wu, L. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20041535 · Cited by 325 · see citing works

Transcriptional regulation of granulocyte and monocyte development

Friedman, A. D. (2002) · Oncogene · doi:10.1038/sj.onc.1205324 · Cited by 325 · see citing works

PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis

Dakic, A., Metcalf, D., Di Rago, L., Mifsud, S., Wu, L., & Nutt, S. L. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20050075 · Cited by 297 · see citing works

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

Carotta, S., Dakic, A., D'Amico, A., Pang, S. H. M., Greig, K. T., Nutt, S. L., & Wu, L. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.005 · Cited by 279 · see citing works

FindPeaks 3.1: a tool for identifying areas of enrichment from massively parallel short-read sequencing technology

Fejes, A. P., Robertson, G., Bilenky, M., Varhol, R., Bainbridge, M., & Jones, S. J. M. (2008) · Bioinformatics · doi:10.1093/bioinformatics/btn305 · Cited by 272 · see citing works

Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates

Walsh, J. C., DeKoter, R. P., Lee, H.-J., Smith, E. D., Lancki, D. W., Gurish, M. F., Friend, D. S., Stevens, R. L., Anastasi, J., & Singh, H. (2002) · Immunity · doi:10.1016/s1074-7613(02)00452-1 · Cited by 262 · see citing works

Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1

Rosenbauer, F., Owens, B. M., Yu, L., Tumang, J. R., Steidl, U., Kutok, J. L., Clayton, L. K., Wagner, K., Scheller, M., Iwasaki, H., et al. (2006) · Nature Genetics · doi:10.1038/ng1679 · Cited by 237 · see citing works

Balance of MafB and PU. 1 specifies alternative macrophage or dendritic cell fate

Bakri, Y., Sarrazin, S., Mayer, U. P., Tillmanns, S., Nerlov, C., Boned, A., & Sieweke, M. H. (2005) · Blood · doi:10.1182/blood-2004-04-1448 · Cited by 187 · see citing works

Constitutive Expression of PU.1 in Fetal Hematopoietic Progenitors Blocks T Cell Development at the Pro-T Cell Stage

Anderson, M. K., Weiss, A. H., Hernandez-Hoyos, G., Dionne, C. J., & Rothenberg, E. V. (2002) · Immunity · doi:10.1016/s1074-7613(02)00277-7 · Cited by 182 · see citing works

Potential Autoregulation of Transcription Factor PU.1 by an Upstream Regulatory Element

Okuno, Y., Huang, G., Rosenbauer, F., Evans, E. K., Radomska, H. S., Iwasaki, H., Akashi, K., Moreau-Gachelin, F., Li, Y., Zhang, P., et al. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.7.2832-2845.2005 · Cited by 174 · see citing works

A Robust and Highly Efficient Immune Cell Reprogramming System

Bussmann, L. H., Schubert, A., Manh, T. V., de Andrés-Aguayo, L., Desbordes, S. C., Parra, M., Zimmermann, T., Rapino, F. A., Rodríguez‐Ubreva, J., Ballestar, E., et al. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.10.004 · Cited by 162 · see citing works

PU.1 is a suppressor of myeloid leukemia, inactivated in mice by gene deletion and mutation of its DNA binding domain

Cook, W. D., McCaw, B. J., Herring, C., John, D. L., Foote, S. J., Nutt, S. L., & Adams, J. M. (2004) · Blood · doi:10.1182/blood-2004-06-2234 · Cited by 140 · see citing works

Expression of the LIM‐homeobox gene LH2 generates immortalized Steel factor‐dependent multipotent hematopoietic precursors

Pinto‐do‐Ó, P., Kolterud, Å., & Carlsson, L. (1998) · The EMBO Journal · doi:10.1093/emboj/17.19.5744 · Cited by 128 · see citing works

Transcription factor complex formation and chromatin fine structure alterations at the murine c-fms (CSF-1 receptor) locus during maturation of myeloid precursor cellsPreprint

Tagoh, H., Himes, R., Clarke, D., Leenen, P. J. M., Riggs, A. D., Hume, D. A., & Bonifer, C. (2002) · Genes & Development · doi:10.1101/gad.222002 · Cited by 123 · see citing works

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

Hoogenkamp, M., Lichtinger, M., Krysinska, H., Lancrin, C., Clarke, D., Williamson, A., Mazzarella, L., Ingram, R., Jorgensen, H., Fisher, A., et al. (2009) · Blood · doi:10.1182/blood-2008-11-191890 · Cited by 121 · see citing works

C/EBPα binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment

Yeamans, C., Wang, D., Paz-Priel, I., Torbett, B. E., Tenen, D. G., & Friedman, A. D. (2007) · Blood · doi:10.1182/blood-2007-03-080291 · Cited by 118 · see citing works

Regulation of the PU.1 gene by distal elements

Li, Y., Okuno, Y., Zhang, P., Radomska, H. S., Chen, H.-M., Iwasaki, H., Akashi, K., Klemsz, M. J., McKercher, S. R., Maki, R. A., et al. (2001) · Blood · doi:10.1182/blood.v98.10.2958 · Cited by 110 · see citing works

Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia

Metcalf, D., Dakic, A., Mifsud, S., Di Rago, L., Wu, L., & Nutt, S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510616103 · Cited by 95 · see citing works

Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

Landry, J., Bonadies, N., Kinston, S., Knezevic, K., Wilson, N. K., Oram, S. H., Janes, M. E., Piltz, S., Hammett, M., Carter, J., et al. (2009) · Blood · doi:10.1182/blood-2008-11-187757 · Cited by 75 · see citing works

The Pu.1 Locus Is Differentially Regulated at the Level of Chromatin Structure and Noncoding Transcription by Alternate Mechanisms at Distinct Developmental Stages of Hematopoiesis

Hoogenkamp, M., Krysinska, H., Ingram, R., Huang, G., Barlow, R. E. L., Clarke, D., Ebralidze, A. K., Zhang, P., Tagoh, H., Cockerill, P. N., et al. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00905-07 · Cited by 63 · see citing works

Stem cell–specific epigenetic priming and B cell–specific transcriptional activation at the mouse Cd19 locus

Walter, K., Bonifer, C., & Tagoh, H. (2008) · Blood · doi:10.1182/blood-2008-02-142786 · Cited by 61 · see citing works

Cell-Type-Specific Activation and Repression of PU.1 by a Complex of Discrete, Functionally Specialized <i>cis</i>-Regulatory Elements

Zarnegar, M. A., Chen, J., & Rothenberg, E. V. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00354-10 · Cited by 52 · see citing works

Transcriptional Regulation of Myelopoiesis

Friedman, A. D. (2002) · International Journal of Hematology · doi:10.1007/bf02982108 · Cited by 43 · see citing works

A novel mode of enhancer evolution: The Tal1 stem cell enhancer recruited a MIR element to specifically boost its activityPreprint

Smith, A. M., Sánchez, M. J., Follows, G., Kinston, S., Donaldson, I. J., Green, A. R., & Göttgens, B. (2008) · Genome Research · doi:10.1101/gr.077008.108 · Cited by 37 · see citing works

Differentiation-dependent Alterations in Histone Methylation and Chromatin Architecture at the Inducible Chicken Lysozyme Gene

Lefevre, P., Lacroix, C., Tagoh, H., Hoogenkamp, M., Melnik, S., Ingram, R., & Bonifer, C. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502422200 · Cited by 36 · see citing works

Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sitesPreprint

Follows, G. A., Dhami, P., Göttgens, B., Bruce, A. W., Campbell, P. J., Dillon, S. C., Smith, A. M., Koch, C. M., Donaldson, I. J., Scott, M. A., et al. (2006) · Genome Research · doi:10.1101/gr.5373606 · Cited by 34 · see citing works

ELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETO

Lausen, J., Liu, S., Fliegauf, M., Lübbert, M., & Werner, M. H. (2005) · Oncogene · doi:10.1038/sj.onc.1209181 · Cited by 32 · see citing works

PU.1(Sfpi1), a pleiotropic regulator expressed from the first embryonic stages with a crucial function in germinal progenitors

Olive, V., Wagner, N., Chan, S. H., Kastner, P., Vannetti, C., Cuzin, F., & Rassoulzadegan, M. (2007) · Development · doi:10.1242/dev.003467 · Cited by 11 · see citing works

Transcription factors: from enhancer binding to developmental control

Spitz, F., & Furlong, E. E. M. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3207 · Cited by 2,227 · see citing works

Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution

Long, H. K., Prescott, S. L., & Wysocka, J. (2016) · Cell · doi:10.1016/j.cell.2016.09.018 · Cited by 945 · see citing works

CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity

Jacoby, E., Nguyen, S. M., Fountaine, T. J., Welp, K. M., Gryder, B. E., Qin, H., Yang, Y., Chien, C. D., Seif, A. E., Lei, H., et al. (2016) · Nature Communications · doi:10.1038/ncomms12320 · Cited by 431 · see citing works

Positive Feedback Between PU.1 and the Cell Cycle Controls Myeloid Differentiation

Kueh, H. Y., Champhekar, A., Nutt, S. L., Elowitz, M. B., & Rothenberg, E. V. (2013) · Science · doi:10.1126/science.1240831 · Cited by 273 · see citing works

Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation

Goode, D. K., Obier, N., Vijayabaskar, M. S., Lie‐A‐Ling, M., Lilly, A. J., Hannah, R., Lichtinger, M., Batta, K., Florkowska, M., Patel, R., et al. (2016) · Developmental Cell · doi:10.1016/j.devcel.2016.01.024 · Cited by 239 · see citing works

The Transcriptional Landscape of Hematopoietic Stem Cell Ontogeny

McKinney‐Freeman, S., Cahan, P., Li, H., Lacadie, S. A., Huang, H.-T., Curran, M. S., Loewer, S., Naveiras, O., Kathrein, K. L., Konantz, M., et al. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.07.018 · Cited by 190 · see citing works

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

Ptasinska, A., Assi, S. A., Mannari, D., James, S. R., Williamson, D., Dunne, J., Hoogenkamp, M., Wu, M., Care, M., McNeill, H., et al. (2012) · Leukemia · doi:10.1038/leu.2012.49 · Cited by 184 · see citing works

Hierarchical Differentiation of Myeloid Progenitors Is Encoded in the Transcription Factor Network

Krumsiek, J., Marr, C., Schroeder, T., & Theis, F. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022649 · Cited by 174 · see citing works

RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis

Lichtinger, M., Ingram, R., Hannah, R., Müller, D., Clarke, D., Assi, S. A., Lie‐A‐Ling, M., Noailles, L., Vijayabaskar, M. S., Wu, M., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.275 · Cited by 180 · see citing works

Sustained PU.1 Levels Balance Cell-Cycle Regulators to Prevent Exhaustion of Adult Hematopoietic Stem Cells

Staber, P. B., Zhang, P., Ye, M., Welner, R. S., Nombela-Arrieta, C., Bach, C., Kerenyi, M., Bartholdy, B. A., Zhang, H., Alberich-Jordà, M., et al. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.01.007 · Cited by 158 · see citing works

The transcription factor PU.1 is critical for viability and function of human brain microglia

Smith, A. M., Gibbons, H. M., Oldfield, R. L., Bergin, P. M., Mee, E. W., Faull, R. L. M., & Dragunow, M. (2013) · Glia · doi:10.1002/glia.22486 · Cited by 141 · see citing works

PU.1 Level-Directed Chromatin Structure Remodeling at the Irf8 Gene Drives Dendritic Cell Commitment

Schönheit, J., Kuhl, C., Gebhardt, M. L., Klett, F. F., Riemke, P., Scheller, M., Huang, G., Naumann, R., Leutz, A., Stocking, C., et al. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.04.007 · Cited by 127 · see citing works

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal

Ptasinska, A., Assi, S. A., Martinez-Soria, N., Imperato, M. R., Piper, J., Cauchy, P., Pickin, A., James, S. R., Hoogenkamp, M., Williamson, D., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.08.024 · Cited by 127 · see citing works

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

Ghani, S., Riemke, P., Schönheit, J., Lenze, D., Stumm, J., Hoogenkamp, M., Lagendijk, A., Heinz, S., Bonifer, C., Bakkers, J., et al. (2011) · Blood · doi:10.1182/blood-2011-02-335141 · Cited by 123 · see citing works

Origin, development, and homeostasis of tissue‐resident macrophages

Haldar, M., & MURPHY, K. M. M. (2014) · Immunological Reviews · doi:10.1111/imr.12215 · Cited by 117 · see citing works

Dynamic Gene Regulatory Networks of Human Myeloid Differentiation

Ramírez, R. N., El-Ali, N. C., Mager, M. A., Wyman, D., Conesa, A., & Mortazavi, A. (2017) · Cell Systems · doi:10.1016/j.cels.2017.03.005 · Cited by 114 · see citing works

Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor α-Bound Enhancers

Carleton, J. B., Berrett, K. C., & Gertz, J. (2017) · Cell Systems · doi:10.1016/j.cels.2017.08.011 · Cited by 113 · see citing works

The Transcription Factor PU.1 is a Critical Regulator of Cellular Communication in the Immune System

Turkistany, S. A., & DeKoter, R. P. (2011) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-011-0147-9 · Cited by 96 · see citing works

Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development

Rothenberg, E. V., Hosokawa, H., & Ungerbäck, J. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00228 · Cited by 99 · see citing works

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia

McKenzie, M. D., Ghisi, M., Oxley, E. P., Ngo, S., Cimmino, L., Esnault, C., Liu, R., Salmon, J. M., Bell, C. C., Ahmed, N., et al. (2019) · Cell Stem Cell · doi:10.1016/j.stem.2019.07.001 · Cited by 91 · see citing works

The RUNX1–PU.1 axis in the control of hematopoiesis

Imperato, M. R., Cauchy, P., Obier, N., & Bonifer, C. (2015) · International Journal of Hematology · doi:10.1007/s12185-015-1762-8 · Cited by 94 · see citing works

Distinct Genetic Networks Orchestrate the Emergence of Specific Waves of Fetal and Adult B-1 and B-2 Development

Montecino‐Rodriguez, E., Fice, M. P., Casero, D., Berent-Maoz, B., Barber, C. L., & Dorshkind, K. A. (2016) · Immunity · doi:10.1016/j.immuni.2016.07.012 · Cited by 86 · see citing works

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

Tirtakusuma, R., Szoltysek, K., Milne, P., Grinev, V. V., Ptasinska, A., Chin, P. S., Meyer, C., Nakjang, S., Hehir‐Kwa, J. Y., Williamson, D., et al. (2022) · Blood · doi:10.1182/blood.2021015036 · Cited by 73 · see citing works

Epigenetic program and transcription factor circuitry of dendritic cell development

Lin, Q., Chauvistré, H., Costa, I. G., Gusmao, E. G., Mitzka, S., Hänzelmann, S., Baying, B., Klisch, T., Moriggl, R., Hennuy, B., et al. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv1056 · Cited by 68 · see citing works

Chromatin priming of genes in development: Concepts, mechanisms and consequences

Bonifer, C., & Cockerill, P. N. (2017) · Experimental Hematology · doi:10.1016/j.exphem.2017.01.003 · Cited by 59 · see citing works

Runx1 is essential at two stages of early murine B-cell development

Niebuhr, B., Kriebitzsch, N., Fischer, M., Behrens, K., Günther, T., Alawi, M., Bergholz, U., Müller, U., Roscher, S., Ziegler, M., et al. (2013) · Blood · doi:10.1182/blood-2013-01-480244 · Cited by 61 · see citing works

Transcriptional Control of Macrophage Identity, Self-Renewal, and Function

Molawi, K., & Sieweke, M. H. (2013) · Advances in immunology · doi:10.1016/b978-0-12-417028-5.00010-7 · Cited by 54 · see citing works

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma

Kreher, S., Bouhlel, M. A., Cauchy, P., Lamprecht, B., Li, S., Grau, M., Hummel, F., Köchert, K., Anagnostopoulos, I., Jöhrens, K., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1406985111 · Cited by 55 · see citing works

The architecture of gene expression: integrating dispersed cis-regulatory modules into coherent regulatory domains

Schwarzer, W., & Spitz, F. (2014) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2014.03.014 · Cited by 49 · see citing works

Epigenetic control of hematopoiesis: the PU.1 chromatin connection

van Riel, B., & Rosenbauer, F. (2014) · Biological Chemistry · doi:10.1515/hsz-2014-0195 · Cited by 47 · see citing works

Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response

Richardson, C. L., Delehanty, L. L., Bullock, G. C., Rival, C. M., Tung, K. S., Kimpel, D. L., Gardenghi, S., Rivella, S., & Goldfarb, A. N. (2013) · Journal of Clinical Investigation · doi:10.1172/jci68487 · Cited by 47 · see citing works

Modest changes in Spi1 dosage reveal the potential for altered microglial function as seen in Alzheimer’s disease

Jones, R. E., Andrews, R., Holmans, P., Hill, M., & Taylor, P. R. (2021) · Scientific Reports · doi:10.1038/s41598-021-94324-z · Cited by 39 · see citing works

5-Azacitidine in aggressive myelodysplastic syndromes regulates chromatin structure at PU.1 gene and cell differentiation capacity

Curik, N., Burda, P., Vargová, K., Pospíšil, V., Beličková, M., Vlckova, P., Savvulidi, F. G., Nečas, E., Hajkova, H., Haškovec, C., et al. (2012) · Leukemia · doi:10.1038/leu.2012.47 · Cited by 45 · see citing works

An autoregulatory enhancer controls mammary-specific STAT5 functions

Metser, G., Shin, H. Y., Wang, C., Yoo, K. H., Oh, S., Villarino, A. V., O’Shea, J. J., Kang, K., & Hennighausen, L. G. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv999 · Cited by 45 · see citing works

Dendritic cell development requires histone deacetylase activity

Chauvistré, H., Küstermann, C., Rehage, N., Klisch, T., Mitzka, S., Felker, P., Rose‐John, S., Zenke, M., & Seré, K. M. (2014) · European Journal of Immunology · doi:10.1002/eji.201344150 · Cited by 45 · see citing works

An enriched network motif family regulates multistep cell fate transitions with restricted reversibility

Ye, Y., Kang, X., Bailey, J., Li, C., & Hong, T. (2019) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1006855 · Cited by 42 · see citing works

Wellington-bootstrap: differential DNase-seq footprinting identifies cell-type determining transcription factors

Piper, J., Assi, S. A., Cauchy, P., Ladroue, C., Cockerill, P. N., Bonifer, C., & Ott, S. (2015) · BMC Genomics · doi:10.1186/s12864-015-2081-4 · Cited by 43 · see citing works

Blockade of prostaglandin E2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells

Singh, P., Hoggatt, J., Hu, P., Speth, J. M., Fukuda, S., BREYER, R. M., & Pelus, L. M. (2011) · Blood · doi:10.1182/blood-2011-03-342428 · Cited by 43 · see citing works

Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes

Jego, G., Lanneau, D., De Thonel, A., Berthenet, K., Hazoumé, A., Droin, N., Hamman, A., Girodon, F., Bellaye, P.-S., Wettstein, G., et al. (2014) · Leukemia · doi:10.1038/leu.2014.63 · Cited by 42 · see citing works

Genome-wide comparison of PU.1 and Spi-B binding sites in a mouse B lymphoma cell line

Solomon, L. A., Li, S. K. H., Piskorz, J., Xu, L., & DeKoter, R. P. (2015) · BMC Genomics · doi:10.1186/s12864-015-1303-0 · Cited by 41 · see citing works

The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells

Staber, P. B., Zhang, P., Ye, M., Welner, R. S., Levantini, E., Di Ruscio, A., Ebralidze, A. K., Bach, C., Zhang, H., Zhang, J., et al. (2014) · Blood · doi:10.1182/blood-2014-01-550855 · Cited by 36 · see citing works

Hematopoiesis and T‐cell specification as a model developmental system

Rothenberg, E. V., Kueh, H. Y., Yui, M. A., & Zhang, J. A. (2016) · Immunological Reviews · doi:10.1111/imr.12417 · Cited by 36 · see citing works

Epigenetic Control of SPI1 Gene by CTCF and ISWI ATPase SMARCA5

Dluhošová, M., Čuřík, N., Vargova, J., Jonasova, A. T., Zikmund, T., & Stopka, T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087448 · Cited by 35 · see citing works

Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells

Nafria, M., Keane, P., Ng, E. S., Stanley, E. G., Elefanty, A. G., & Bonifer, C. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107691 · Cited by 34 · see citing works

From remote enhancers to gene regulation: charting the genome's regulatory landscapes

Symmons, O., & Spitz, F. (2013) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2012.0358 · Cited by 34 · see citing works

Plenary Perspective: The complexity of constitutive and inducible gene expression in mononuclear phagocytes

Hume, D. A. (2012) · Journal of Leukocyte Biology · doi:10.1189/jlb.0312166 · Cited by 33 · see citing works

Ikaros represses and activates PU.1 cell-type-specifically through the multifunctional Sfpi1 URE and a myeloid specific enhancer

Zarnegar, M. A., & Rothenberg, E. V. (2012) · Oncogene · doi:10.1038/onc.2011.597 · Cited by 31 · see citing works

Integration of cytokine and transcription factor signals in hematopoietic stem cell commitment

Sarrazin, S., & Sieweke, M. H. (2011) · Seminars in Immunology · doi:10.1016/j.smim.2011.08.011 · Cited by 31 · see citing works

Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice

Bašová, P., Pospíšil, V., Savvulidi, F. G., Burda, P., Vargová, K., Staněk, L., Dluhošová, M., Kužmová, E., Jonasova, A. T., Steidl, U. G., et al. (2013) · Oncogene · doi:10.1038/onc.2013.414 · Cited by 28 · see citing works

Nfix Expression Critically Modulates Early B Lymphopoiesis and Myelopoiesis

O’Connor, C., Campos, J., Osinski, J. M., Gronostajski, R. M., Michie, A. M., & Keeshan, K. (2015) · PLoS ONE · doi:10.1371/journal.pone.0120102 · Cited by 28 · see citing works

Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification

Wilkinson, A. C., Kawata-Matsuura, V. K. S., Schütte, J., Gao, X., Antoniou, S., Baumann, C., Woodhouse, S., Hannah, R., Tanaka, Y., Swiers, G., et al. (2014) · Development · doi:10.1242/dev.115709 · Cited by 27 · see citing works

A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification

Edginton-White, B., Maytum, A., Kellaway, S., Goode, D., Keane, P., Pagnuco, I., Assi, S. A., Ames, L., Clarke, M., Cockerill, P., et al. (2022) · bioRxiv · doi:10.1038/s41467-023-35910-9 · Cited by 22 · see citing works

LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage

Stanulović, V. S., Cauchy, P., Assi, S. A., & Hoogenkamp, M. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx573 · Cited by 26 · see citing works

Oncogenic microRNA-155 and its target PU.1: an integrative gene expression study in six of the most prevalent lymphomas

Hušková, H., Korecka, K., Karban, J., Vargova, J., Vargová, K., Dusílková, N., Trněný, M., & Stopka, T. (2015) · International Journal of Hematology · doi:10.1007/s12185-015-1847-4 · Cited by 25 · see citing works

Runx1 promotes murine erythroid progenitor proliferation and inhibits differentiation by preventing Pu.1 downregulation

Willcockson, M. A., Taylor, S. J., Ghosh, S., Healton, S. E., Wheat, J. C., Wilson, T. J., Steidl, U. G., & Skoultchi, A. I. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1901122116 · Cited by 23 · see citing works

Krox20 hindbrain regulation incorporates multiple modes of cooperation between cis-acting elements

Thierion, E., Men, J. L., Collombet, S., Hernandez, C., Coulpier, F., Torbey, P., Thomas‐Chollier, M., Noordermeer, D., Charnay, P., & Gilardi‐Hebenstreit, P. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006903 · Cited by 23 · see citing works

Models of dendritic cell development correlate ontogeny with function

Anderson, D. A., & MURPHY, K. M. M. (2019) · Advances in immunology · doi:10.1016/bs.ai.2019.09.001 · Cited by 22 · see citing works

Genetic architecture of gene expression in the chicken

Stanley, D., Watson‐Haigh, N. S., Cowled, C. J., & Moore, R. J. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-13 · Cited by 22 · see citing works

Hematopoietic transcriptional mechanisms: From locus-specific to genome-wide vantage points

DeVilbiss, A., Sanalkumar, R., Johnson, K. D., Keleş, S., & Bresnick, E. H. (2014) · Experimental Hematology · doi:10.1016/j.exphem.2014.05.004 · Cited by 21 · see citing works

GATA-1 Inhibits PU.1 Gene via DNA and Histone H3K9 Methylation of Its Distal Enhancer in Erythroleukemia

Burda, P., Vargova, J., Čuřík, N., Šálek, C., Papadopoulos, G. L., Strouboulis, J., & Stopka, T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0152234 · Cited by 21 · see citing works

Temporal autoregulation during human PU.1 locus SubTAD formation.

Schuetzmann, D., Walter, C., van Riel, B., Kruse, S., König, T., Erdmann, T., Tönges, A., Bindels, E., Weilemann, A., Gebhard, C., et al. (2018) · Blood · doi:10.1182/blood-2018-02-834721 · Cited by 19 · see citing works

STAT5-Driven Enhancers Tightly Control Temporal Expression of Mammary-Specific Genes

Shin, H. Y., Hennighausen, L. G., & Yoo, K. H. (2018) · Journal of Mammary Gland Biology and Neoplasia · doi:10.1007/s10911-018-9418-y · Cited by 20 · see citing works

Logic and lineage impacts on functional transcription factor deployment for T-cell fate commitment

Rothenberg, E. V. (2021) · Biophysical Journal · doi:10.1016/j.bpj.2021.04.002 · Cited by 16 · see citing works

The analysis of novel distal Cebpa enhancers and silencers using a transcriptional model reveals the complex regulatory logic of hematopoietic lineage specification

Bertolino, E., Reinitz, J., & Manu (2016) · Developmental Biology · doi:10.1016/j.ydbio.2016.02.030 · Cited by 17 · see citing works

Dynamic control of the T-cell specification gene regulatory network

Rothenberg, E. V. (2019) · Current Opinion in Systems Biology · doi:10.1016/j.coisb.2019.10.012 · Cited by 16 · see citing works

Multi-scale Dynamical Modeling of T Cell Development from an Early Thymic Progenitor State to Lineage Commitment

Olariu, V., Yui, M. A., Krupinski, P., Zhou, W., Deichmann, J., Andersson, E., Rothenberg, E. V., & Peterson, C. (2021) · Cell Reports · doi:10.1016/j.celrep.2020.108622 · Cited by 15 · see citing works

Isocitrate treatment of acute anemia of inflammation in a mouse model

Kim, A., Fung, E., Parikh, S. G., Gabayan, V. R., Nemeth, E., & Ganz, T. (2015) · Blood Cells Molecules and Diseases · doi:10.1016/j.bcmd.2015.09.007 · Cited by 15 · see citing works

Chromatin Dynamics during Differentiation of Myeloid Cells

Schönheit, J., Leutz, A., & Rosenbauer, F. (2014) · Journal of Molecular Biology · doi:10.1016/j.jmb.2014.08.015 · Cited by 15 · see citing works

Regulatory sharing between estrogen receptor α bound enhancers

Carleton, J. B., Ginley-Hidinger, M., Berrett, K. C., Layer, R. M., Quinlan, A. R., & Gertz, J. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa454 · Cited by 15 · see citing works

Cisinteractions in theIrf8locus regulate stage-dependent enhancer activationPreprint

Liu, T., Ou, F., Belk, J. A., Bagadia, P., Anderson, D. A., Durai, V., Yao, W., Satpathy, A. T., Murphy, T. L., & MURPHY, K. M. M. (2023) · Genes & Development · doi:10.1101/gad.350339.122 · Cited by 14 · see citing works

Labelled regulatory elements are pervasive features of the macrophage genome and are dynamically utilized by classical and alternative polarization signals

Horváth, A., Dániel, B., Széles, L., Cuaranta‐Monroy, I., Czimmerer, Z., Ozgyin, L., Steiner, L., Kiss, M., Simándi, Z., Póliska, S., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz118 · Cited by 13 · see citing works

hnRNP K in PU.1-containing complexes recruited at theCD11bpromoter: a distinct role in modulating granulocytic and monocytic differentiation of AML-derived cells

Nika, E., Brugnoli, F., Piazzi, M., Lambertini, E., Grassilli, S., Bavelloni, A., Piva, R., Capitani, S., & Bertagnolo, V. (2014) · Biochemical Journal · doi:10.1042/bj20140358 · Cited by 13 · see citing works

Unveiling the complexity of transcription factor networks in hematopoietic stem cells: implications for cell therapy and hematological malignancies

Benyoucef, A., Haigh, J. J., & Brand, M. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1151343 · Cited by 12 · see citing works

Genome-wide profiling reveals epigenetic inactivation of the PU.1 pathway by histone H3 lysine 27 trimethylation in cytogenetically normal myelodysplastic syndrome

Cheng, J. X., Anastasi, J., Watanabe, K. Q., Kleinbrink, E. L., Grimley, E. C., Knibbs, R., Shen, Q. J., & Vardiman, J. W. (2013) · Leukemia · doi:10.1038/leu.2013.45 · Cited by 12 · see citing works

Phenotypic stability and plasticity in GMP-derived cells as determined by their underlying regulatory network

Ramírez, C., & Mendoza, L. (2017) · Bioinformatics · doi:10.1093/bioinformatics/btx736 · Cited by 12 · see citing works

PTEN regulates hematopoietic lineage plasticity via PU.1-dependent chromatin accessibility

Xu, Z., He, L., Wu, Y., Yang, L., Li, C., & Wu, H. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112967 · Cited by 11 · see citing works

Chromatin priming elements direct tissue-specific gene activity before hematopoietic specification

Maytum, A., Edginton‐White, B., Keane, P., Cockerill, P. N., Cazier, J., & Bonifer, C. (2023) · Life Science Alliance · doi:10.26508/lsa.202302363 · Cited by 10 · see citing works

Pin1‐Mediated Prolyl Isomerization of Runx1 Affects PU.1 Expression in Pre‐Monocytes

Islam, R., Yoon, W.-J., Woo, K., Baek, J., & Ryoo, H. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24462 · Cited by 10 · see citing works

Stress hematopoiesis is regulated by the Krüppel-like transcription factor ZBP-89

Li, X.-G., Romain, R. D., Park, D., Scadden, D. T., Merchant, J., & Arnaout, M. (2014) · Stem Cells · doi:10.1002/stem.1598 · Cited by 11 · see citing works

Applying attractor dynamics to infer gene regulatory interactions involved in cellular differentiation

Ghaffarizadeh, A., Podgorski, G. J., & Flann, N. S. (2017) · Biosystems · doi:10.1016/j.biosystems.2016.12.004 · Cited by 9 · see citing works

Illuminating stem cell transcription factor dynamics: long-term single-cell imaging of fluorescent protein fusions

Etzrodt, M., & Schroeder, T. (2017) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2017.12.006 · Cited by 9 · see citing works

Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation

Ahmed, N., Etzrodt, M., Dettinger, P., Kull, T., Loeffler, D., Hoppe, P. S., Chavez, J. S., Zhang, Y., Camargo Ortega, G., Hilsenbeck, O., et al. (2022) · Journal of Experimental Medicine · doi:10.1084/jem.20202490 · Cited by 9 · see citing works

From Genotype to Phenotype: How Enhancers Control Gene Expression and Cell Identity in Hematopoiesis

Mulet-Lazaro, R., & Delwel, R. (2023) · HemaSphere · doi:10.1097/hs9.0000000000000969 · Cited by 6 · see citing works

The epigenetic circle: feedback loops in the maintenance of cellular memory

Tomljanović, M., Muflihah, C. H., Rajkovski, D., & Mikulski, P. (2025) · Epigenetics & Chromatin · doi:10.1186/s13072-025-00621-6 · Cited by 10 · see citing works

Dynamic changes in chromatin conformation at the TNF transcription start site in T helper lymphocyte subsets

Shebzukhov, Y. V., Horn, K., Brazhnik, K., Drutskaya, M. S., Kuchmiy, A. A., Kuprash, D. V., & Nedospasov, S. A. (2013) · European Journal of Immunology · doi:10.1002/eji.201243297 · Cited by 9 · see citing works

Transcriptional Regulation of the Lineage-Determining Gene PU.1 in Normal and Malignant Hematopoiesis: Current Understanding and Therapeutic Perspective

Korczmar, E., Bookstaver, A. K., Ober, E., Goldfarb, A. N., Tenen, D. G., & Trinh, B. Q. (2024) · Frontiers in Bioscience-Scholar · doi:10.31083/j.fbs1602010 · Cited by 8 · see citing works

Data-driven modeling predicts gene regulatory network dynamics during the differentiation of multipotential hematopoietic progenitors

Handzlik, J. E., & Manu (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009779 · Cited by 8 · see citing works

Irreversibility of T-Cell Specification: Insights from Computational Modelling of a Minimal Network Architecture

Manesso, E., Kueh, H. Y., Freedman, G., Rothenberg, E. V., & Peterson, C. (2016) · PLoS ONE · doi:10.1371/journal.pone.0161260 · Cited by 8 · see citing works

Combined Approach to Leukemic Differentiation Using Transcription Factor PU.1-Enhancing Agents

Bašová, P., Paszeková, H., Minařík, Ľ., Dluhošová, M., Burda, P., & Stopka, T. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23126729 · Cited by 7 · see citing works

Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity

Garcia, G. T., Kowenz‐Leutz, E., Tian, T. V., Klonizakis, A., Lerner, J., de Andrés-Aguayo, L., Sapozhnikova, V., Berenguer, C., Plana-Carmona, M., Vila-Casadesús, M., et al. (2023) · eLife · doi:10.7554/elife.83951 · Cited by 7 · see citing works

Chromatin structure and 3D architecture define the differential functions of PU.1 regulatory elements in blood cell lineages

Qiu, K., Vu, D. C., Wang, L., Nguyen, N. N., Bookstaver, A. K., Sol‐Church, K., Li, H., Dinh, T. N., Goldfarb, A. N., Tenen, D. G., et al. (2024) · Epigenetics & Chromatin · doi:10.1186/s13072-024-00556-4 · Cited by 6 · see citing works

How haematopoiesis research became a fertile ground for regulatory network biology as pioneered by Eric Davidson

Rothenberg, E. V., & Göttgens, B. (2020) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000628 · Cited by 6 · see citing works

The Making of a cDC1 : Precision Programming of Progenitor Potential

Murphy, T. L., & MURPHY, K. M. M. (2025) · Immunological Reviews · doi:10.1111/imr.70081 · Cited by 7 · see citing works

Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages

Yau, E., Chen, Y., Song, C., Webb, J., Carillo, M., Kawasawa, Y. I., Tang, Z., Takahashi, Y., Umstead, T. M., Dovat, S., et al. (2021) · Immunobiology · doi:10.1016/j.imbio.2021.152150 · Cited by 5 · see citing works

A network-based computational framework to predict and differentiate functions for gene isoforms using exon-level expression data

Wang, D., Zou, X., & Au, K. F. (2020) · Methods · doi:10.1016/j.ymeth.2020.06.005 · Cited by 4 · see citing works

Long-term immune and epigenetic dysregulation following COVID-19

Sidiropoulou, C., Poulakou, G., Kyriazopoulou, E., Tasouli, E., Giannitsioti, E., Strikou, A., Τσιλικά, Μ., Christaki, E., Rapti, V., Evangelopoulou, V., et al. (2025) · Clinical Immunology · doi:10.1016/j.clim.2025.110656 · Cited by 3 · see citing works

The C/EBPα-(PU.1- LOUP ) regulatory circuit regulates monocyte/macrophage development and immune functions

Waliullah, A. S. M., Nguyen, T.-A., Dziegielewska, B., Zhang, J., Qiu, K., Tran, M. L., Nguyen, N., Wang, L., Pan, A., Nong, M. K., et al. (2026) · Blood · doi:10.1182/blood.2025030667 · Cited by 3 · see citing works

BURN INJURY RESULTS IN MYELOID PRIMING DURING EMERGENCY HEMATOPOIESIS

Johnson, R. M., Galicia, K. E., Wang, H., Gonzalez, R., Choudhry, M. A., & Kubasiak, J. (2024) · Shock · doi:10.1097/shk.0000000000002458 · Cited by 3 · see citing works

Why detailed model gene studies in higher eukaryotes are still necessary

Bonifer, C. (2013) · Immunology · doi:10.1111/imm.12066 · Cited by 3 · see citing works

Shared transcription factors contribute to distinct cell fates

Ng, F., Calero‐Nieto, F. J., & Göttgens, B. (2014) · Transcription · doi:10.4161/21541264.2014.978173 · Cited by 2 · see citing works

Autoregulation of the Transcription Factor PU.1 Via Its Evolutionarily Conserved Upstream Regulatory Element Is Critical in Adult Mouse Hematopoiesis.

Staber, P. B., Zhang, P., Ye, M., Huang, G., Bartholdy, B., Ruscio, A. D., Ebralidze, A. K., & Tenen, D. G. (2009) · Blood · doi:10.1182/blood.v114.22.1468.1468

Potential Autoregulation of Transcription Factor PU.1 by an Upstream Regulatory Element

Okuno, Y., Huang, G., Rosenbauer, F., Evans, E. K., Radomska, H. S., Iwasaki, H., Akashi, K., Moreau-Gachelin, F., Li, Y., Zhang, P., et al. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.7.2832-2845.2005 · Cited by 174 · see citing works

Unterschiedliche Autoregulation am PU.1 Lokus in B -Zellen und myeloischen Zellen

Leddin, M. (2011) · doi:10.18452/16546

Regulation of the PU.1 gene by distal elements

Li, Y., Okuno, Y., Zhang, P., Radomska, H. S., Chen, H.-M., Iwasaki, H., Akashi, K., Klemsz, M. J., McKercher, S. R., Maki, R. A., et al. (2001) · Blood · doi:10.1182/blood.v98.10.2958 · Cited by 110 · see citing works

Untitled work

(1995) · PubMed · Cited by 206 · see citing works