Li, Xiaoxia

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

Zhou, W., Ke, S. Q., Huang, Z., Flavahan, W., Fang, X., Paul, J., Wu, L., Sloan, A. E., McLendon, R. E., Li, X., et al. (2015) · Nature Cell Biology

Immune cells in cancerGlioma Diagnosis and Treatment

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Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability

Lee, J. S., Tato, C. M., Joyce-Shaikh, B., Gulen, M. F., Cayatte, C., Chen, Y., Blumenschein, W. M., Judo, M., Ayanoglu, G., McClanahan, T. K., et al. (2015) · Immunity

Psoriasis: Treatment and PathogenesisInflammatory Bowel Disease

Cited by 760

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease

Qian, Y., Liu, C., Hartupee, J., Altuntas, C. Z., Gulen, M. F., Jane-wit, D., Xiao, J., Lu, Y., Giltiay, N., Liu, J., et al. (2007) · Nature Immunology

Psoriasis: Treatment and PathogenesisNF-κB Signaling Pathways

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Astrocyte-restricted ablation of interleukin-17-induced ACT1-mediated signaling ameliorates autoimmune encephalomyelitis

Kang, Z., Altuntas, C. Z., Gulen, M. F., Liu, C., Giltiay, N., Qin, H., Liu, L., Qian, W., Ransohoff, R. M., Bergmann, C., et al. (2010) · Immunity

Multiple Sclerosis Research StudiesPsoriasis: Treatment and Pathogenesis

Cited by 297

An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis

Boisson, B., Wang, C., Pedergnana, V., Wu, L., Cypowyj, S., Rybojad, M., Belkadi, A., Picard, C., Abel, L., Fieschi, C., et al. (2013) · Immunity

Immunodeficiency and Autoimmune DisordersPsoriasis: Treatment and Pathogenesis

Cited by 293

Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)

Sun, D., Novotny, M., Bulek, K., Liu, C., Li, X., & Hamilton, T. (2011) · Nature Immunology

RNA Research and SplicingCytokine Signaling Pathways and Interactions

Cited by 232

Act1, a U-box E3 Ubiquitin Ligase for IL-17 Signaling

Liu, C., Qian, W., Qian, Y., Giltiay, N. V., Lu, Y., Swaidani, S., Misra, S., Deng, L., Chen, Z. J., & Li, X. (2009) · Science Signaling

NF-κB Signaling PathwaysPsoriasis: Treatment and Pathogenesis

Cited by 224

Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells

Kang, Z., Wang, C., Zepp, J., Wu, L., Sun, K., Zhao, J., Chandrasekharan, U., DiCorleto, P. E., Trapp, B. D., Ransohoff, R. M., et al. (2013) · Nature Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 218

The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation

Bulek, K., Liu, C., Swaidani, S., Wang, L., Page, R. C., Gulen, M. F., Herjan, T., Abbadi, A., Qian, W., Sun, D., et al. (2011) · Nature Immunology

NF-κB Signaling PathwaysCytokine Signaling Pathways and Interactions

Cited by 192

Act1, a negative regulator in CD40- and BAFF-mediated B cell survival

Qian, Y., Qin, J., Cui, G., Naramura, M., Snow, E. C., Ware, C. F., Fairchild, R. L., Omori, S. A., Rickert, R. C., Scott, M., et al. (2004) · Immunity

NF-κB Signaling PathwaysT-cell and B-cell Immunology

Cited by 143

IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling

Herjan, T., Hong, L., Bubenik, J., Bulek, K., Qian, W., Liu, C., Li, X., Chen, X., Yang, H., Ouyang, S., et al. (2018) · Nature Immunology

RNA Research and SplicingCytokine Signaling Pathways and Interactions

Cited by 121

AMP-activated protein kinase promotes the differentiation of endothelial progenitor cells

Li, X., Han, Y., Pang, W., Li, C., Xie, X., Shyy, J. Y.-J., & Zhu, Y. (2008) · Arteriosclerosis Thrombosis and Vascular Biology

Angiogenesis and VEGF in CancerMesenchymal stem cell research

Cited by 113

IRAK4 Kinase Activity Is Redundant for Interleukin-1 (IL-1) Receptor-associated Kinase Phosphorylation and IL-1 Responsiveness

Qin, J., Jiang, Z., Qian, Y., Casanova, J.-L., & Li, X. (2004) · Journal of Biological Chemistry

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 110

IL-17R-EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells

Chen, X., Cai, G., Liu, C., Zhao, J., Gu, C., Wu, L., Hamilton, T. A., Zhang, C.-J., Ko, J., Zhu, L., et al. (2019) · Journal of Experimental Medicine

Cytokine Signaling Pathways and InteractionsPsoriasis: Treatment and Pathogenesis

Cited by 106

Caregiver-Delivered Stroke Rehabilitation in Rural China: The RECOVER Randomized Controlled Trial

Zhou, B., Zhang, J., Zhao, Y., Li, X., Anderson, C. S., Xie, B., Wang, N., Zhang, Y., Tang, X., Prvu Bettger, J., et al. (2019) · Stroke

Stroke Rehabilitation and RecoveryMedical Practices and Rehabilitation

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HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization

Herjan, T., Yao, P., Qian, W., Li, X., Liu, C., Bulek, K., Sun, D., Yang, W.-P., Zhu, J., He, A., et al. (2013) · The Journal of Immunology

RNA Research and SplicingCytokine Signaling Pathways and Interactions

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IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast-mediated immune exclusion

Chen, X., Zhao, J., Herjan, T., Hong, L., Liao, Y., Liu, C., Vasu, K., Wang, H., Thompson, A., Fox, P. L., et al. (2022) · Journal of Experimental Medicine

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 53

Hydrogen Peroxide-Induced Senescence Reduces the Wound Healing-Promoting Effects of Mesenchymal Stem Cell-Derived Exosomes Partially via miR-146a

Xu, M., Su, X., Xiao, X., Yu, H., Li, X., Keating, A., Wang, S., & Zhao, R. C. (2021) · Aging and disease

Extracellular vesicles in diseaseWound Healing and Treatments

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Cell type- and stimulus-specific mechanisms for post-transcriptional control of neutrophil chemokine gene expression

Hamilton, T., Li, X., Novotny, M., Pavicic, P. G., Datta, S., Zhao, C., Hartupee, J., & Sun, D. (2011) · Journal of Leukocyte Biology

RNA Research and SplicingChemokine receptors and signaling

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N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/β-catenin signaling

Shi, X., Cen, Y., Shan, L., Tian, L., Zhu, E., Yuan, H., Li, X., Liu, Y., & Wang, B. (2022) · Stem Cell Research & Therapy

Bone Metabolism and DiseasesWnt/β-catenin signaling in development and cancer

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