Gong, Cheng-Xin

Tau pathology in Alzheimer disease and other tauopathies

Iqbal, K., del C. Alonso, A., Chen, S., Chohan, M. O., El-Akkad, E., Gong, C.-X., Khatoon, S., Li, B., Liu, F., Rahman, A., et al. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,037

Tau and neurodegenerative disease: the story so far

Iqbal, K., Liu, F., & Gong, C.-X. (2016) · Nature Reviews Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 806

O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease

Liu, F., Iqbal, K., Grundke-Iqbal, I., Hart, G. W., & Gong, C.-X. (2004) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsGlycosylation and Glycoproteins Research

Cited by 775

Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

Liu, F., Grundke‐Iqbal, I., Iqbal, K., & Gong, C. (2005) · European Journal of Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 759

Mechanisms of tau-induced neurodegeneration

Iqbal, K., Liu, F., Gong, C.-X., Alonso, A. D. C., & Grundke-Iqbal, I. (2009) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 628

Phosphoprotein Phosphatase Activities in Alzheimer Disease Brain

Gong, C., Singh, T. J., Grundke‐Iqbal, I., & Iqbal, K. (1993) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsProtein Tyrosine Phosphatases

Cited by 527

Deregulation of sphingolipid metabolism in Alzheimer’s disease

He, X., Huang, Y., Li, B., Gong, C.-X., & Schuchman, E. H. (2010) · Neurobiology of Aging

Sphingolipid Metabolism and SignalingAlzheimer's disease research and treatments

Cited by 516

Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease

Liu, F., Shi, J., Tanimukai, H., Gu, J., Gu, J., Grundke-Iqbal, I., Iqbal, K., & Gong, C.-X. (2009) · Brain

Alzheimer's disease research and treatmentsGlycosylation and Glycoproteins Research

Cited by 439

Post-translational modifications of tau protein in Alzheimer’s disease

Gong, C.-X., Liu, F., Grundke-Iqbal, I., & Iqbal, K. (2005) · Journal of Neural Transmission

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 437

Phosphorylation of Microtubule-associated Protein Tau Is Regulated by Protein Phosphatase 2A in Mammalian Brain

Gong, C.-X., Lidsky, T., Wegiel, J., Zuck, L., Grundke-Iqbal, I., & Iqbal, K. (2000) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 405

Tau exon 10 alternative splicing and tauopathies

Liu, F., & Gong, C.-X. (2008) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsRNA Research and Splicing

Cited by 323

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in down syndrome

Liu, F., Liang, Z., Wegiel, J., Hwang, Y., Iqbal, K., Grundke‐Iqbal, I., Ramakrishna, N., & Gong, C. (2008) · The FASEB Journal

Alzheimer's disease research and treatmentsDown syndrome and intellectual disability research

Cited by 272

Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B

Wang, J.-Z., Gong, C.-X., Zaidi, T., Grundke-Iqbal, I., & Iqbal, K. (1995) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 269

Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation

Liu, F., Li, B., Tung, E., Grundke‐Iqbal, I., Iqbal, K., & Gong, C. (2007) · European Journal of Neuroscience

Alzheimer's disease research and treatmentsMicrotubule and mitosis dynamics

Cited by 208

Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain

Bennecib, M., Gong, C.-X., Grundke-Iqbal, I., & Iqbal, K. (2000) · FEBS Letters

Alzheimer's disease research and treatmentsProtein Kinase Regulation and GTPase Signaling

Cited by 184

From Chronic Cerebral Hypoperfusion to Alzheimer-Like Brain Pathology and Neurodegeneration

Zhao, Y., & Gong, C.-X. (2015) · Cellular and Molecular Neurobiology

Neurological Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 180

Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease

Liu, F., Zaidi, T., Iqbal, K., Grundke-Iqbal, I., Merkle, R. K., & Gong, C.-X. (2002) · FEBS Letters

Alzheimer's disease research and treatmentsGlycosylation and Glycoproteins Research

Cited by 167

Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation

Wang, Y., Yang, R., Gu, J., Yin, X., Jin, N., Xie, S., Wang, Y., Chang, H., Qian, W., Shi, J., et al. (2015) · Neurobiology of Aging

Alzheimer's disease research and treatmentsProtein Kinase Regulation and GTPase Signaling

Cited by 134

Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice

Dai, C.-L., Hu, W., Tung, Y. C., Liu, F., Gong, C.-X., & Iqbal, K. (2018) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 99

Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn down syndrome mice

Yin, X., Jin, N., Shi, J., Zhang, Y., Wu, Y., Gong, C.-X., Iqbal, K., & Liu, F. (2017) · Scientific Reports

Alzheimer's disease research and treatmentsDown syndrome and intellectual disability research

Cited by 93

Dysregulation of tau phosphorylation in mouse brain during excitotoxic damage.

Liang, Z., Liu, F., Iqbal, K., Grundke-Iqbal, I., & Gong, C.-X. (2009) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 73