Zhang, Yi

Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing

Cao, R., Wang, L., Wang, H., Xia, L., Erdjument-Bromage, H., Tempst, P., Jones, R. S., & Zhang, Y. (2002) · Science

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 3,775

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

Ito, S., Shen, L., Dai, Q., Wu, S. C., Collins, L. B., Swenberg, J. A., He, C., & Zhang, Y. (2011) · Science

Epigenetics and DNA MethylationRNA modifications and cancer

Cited by 3,451

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

Ran, F. A., Hsu, P. D., Lin, C.-Y., Gootenberg, J. S., Konermann, S., Trevino, A. E., Scott, D. A., Inoue, A., Matoba, S., Zhang, Y., et al. (2013) · Cell

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 3,299

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Xu, W., Yang, H., Liu, Y., Yang, Y., Wang, P., Kim, S.-H., Ito, S., Yang, C., Wang, P., Xiao, M.-T., et al. (2011) · Cancer Cell

Glioma Diagnosis and TreatmentEpigenetics and DNA Methylation

Cited by 2,875

TET-mediated active DNA demethylation: mechanism, function and beyond

Wu, X., & Zhang, Y. (2017) · Nature Reviews Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,661

TET enzymes, TDG and the dynamics of DNA demethylation

Kohli, R. M., & Zhang, Y. (2013) · Nature

Epigenetics and DNA MethylationDNA Repair Mechanisms

Cited by 1,623

JmjC-domain-containing proteins and histone demethylation

Klose, R. J., Kallin, E. M., & Zhang, Y. (2006) · Nature Reviews Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,290

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

Zhang, Y., Ng, H.-H., Erdjument-Bromage, H., Tempst, P., Bird, A., & Reinberg, D. (1999) · Genes & Development

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,103

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

Wu, H., & Zhang, Y. (2014) · Cell

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 1,065

New nomenclature for chromatin-modifying enzymes

Allis, C. D., Berger, S. L., Cote, J., Dent, S., Jenuwien, T., Kouzarides, T., Pillus, L., Reinberg, D., Shi, Y., Shiekhattar, R., et al. (2007) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 957

G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis

Feldman, N., Gerson, A., Fang, J., Li, E., Zhang, Y., Shinkai, Y., Cedar, H., & Bergman, Y. (2006) · Nature Cell Biology

Epigenetics and DNA MethylationPluripotent Stem Cells Research

Cited by 651

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells

Wu, H., D’Alessio, A. C., Ito, S., Xia, K., Wang, Z., Cui, K., Zhao, K., Eve Sun, Y., & Zhang, Y. (2011) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 646

Dnmt3a-Dependent Nonpromoter DNA Methylation Facilitates Transcription of Neurogenic Genes

Wu, H., Coskun, V., Tao, J., Xie, W., Ge, W., Yoshikawa, K., Li, E., Zhang, Y., & Sun, Y. E. (2010) · Science

Epigenetics and DNA MethylationNeurogenesis and neuroplasticity mechanisms

Cited by 604

Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity

Chen, R., Wu, X., Jiang, L., & Zhang, Y. (2017) · Cell Reports

Single-cell and spatial transcriptomicsRegulation of Appetite and Obesity

Cited by 592

Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex

Zhang, Y., Iratni, R., Erdjument-Bromage, H., Tempst, P., & Reinberg, D. (1997) · Cell

Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research

Cited by 578

Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics

Shen, L., Wu, H., Diep, D., Yamaguchi, S., D’Alessio, A. C., Fung, H.-L., Zhang, K., & Zhang, Y. (2013) · Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 497

Decoding molecular and cellular heterogeneity of mouse nucleus accumbens

Chen, R., Blosser, T. R., Djekidel, M. N., Hao, J., Bhattacherjee, A., Chen, W., Tuesta, L. M., Zhuang, X., & Zhang, Y. (2021) · Nature Neuroscience

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 191

Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction

Bhattacherjee, A., Djekidel, M. N., Chen, R., Chen, W., Tuesta, L. M., & Zhang, Y. (2019) · Nature Communications

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 174

Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain

Bhattacherjee, A., Zhang, C., Watson, B. R., Djekidel, M. N., Moffitt, J. R., & Zhang, Y. (2023) · Nature Neuroscience

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 71

Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10–positive leukemias

Lin, Y.-H., Kakadia, P. M., Chen, Y., Li, Y.-Q., Deshpande, A. J., Buske, C., Zhang, K.-L., Zhang, Y., Xu, G.-L., & Bohlander, S. K. (2009) · Blood

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 64