Ferrara, Napoleone

The biology of VEGF and its receptors

Ferrara, N., Gerber, H.-P., & LeCouter, J. (2003) · Nature Medicine

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 9,591

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

Kim, K. J., Li, B., Winer, J., Armanini, M., Gillett, N., Phillips, H. S., & Ferrara, N. (1993) · Nature

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 3,605

VEGF in signaling and disease: beyond discovery and development

Apte, R. S., Chen, D. S., & Ferrara, N. (2019) · Cell

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 2,721

Angiogenesis as a therapeutic target

Ferrara, N., & Kerbel, R. S. (2005) · Nature

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 2,653

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

Ferrara, N., Hillan, K. J., Gerber, H.-P., & Novotny, W. (2004) · Nature Reviews Drug Discovery

Angiogenesis and VEGF in CancerMonoclonal and Polyclonal Antibodies Research

Cited by 2,625

HIF-1α is essential for myeloid cell-mediated inflammation

Cramer, T., Yamanishi, Y., Clausen, B. E., Förster, I., Pawlinski, R., Mackman, N., Haase, V. H., Jaenisch, R., Corr, M., Nizet, V., et al. (2003) · Cell

Cancer, Hypoxia, and MetabolismImmune cells in cancer

Cited by 2,046

VEGF and the quest for tumour angiogenesis factors

Ferrara, N. (2002) · Nature Reviews Cancer

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 1,536

Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms.

Houck, K. A., Leung, D. W., Rowland, A. M., Winer, J., & Ferrara, N. (1992) · Journal of Biological Chemistry

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 1,127

Clinical applications of angiogenic growth factors and their inhibitors

Ferrara, N., & Alitalo, K. (1999) · Nature Medicine

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 1,004

Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells

Shojaei, F., Wu, X., Malik, A. K., Zhong, C., Baldwin, M. E., Schanz, S., Fuh, G., Gerber, H.-P., & Ferrara, N. (2007) · Nature Biotechnology

Angiogenesis and VEGF in CancerImmune cells in cancer

Cited by 849

Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration

FERRARA, N., DAMICO, L., SHAMS, N., LOWMAN, H., & KIM, R. (2006) · Retina

Retinal Diseases and TreatmentsAngiogenesis and VEGF in Cancer

Cited by 849

Differential Transcriptional Regulation of the Two Vascular Endothelial Growth Factor Receptor Genes

Gerber, H.-P., Condorelli, F., Park, J., & Ferrara, N. (1997) · Journal of Biological Chemistry

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 794

Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease

Argaw, A. T., Asp, L., Zhang, J., Navrazhina, K., Pham, T., Mariani, J. N., Mahase, S., Dutta, D. J., Seto, J., Kramer, E. G., et al. (2012) · Journal of Clinical Investigation

Barrier Structure and Function StudiesMultiple Sclerosis Research Studies

Cited by 733

Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells.

Pertovaara, L., Kaipainen, A., Mustonen, T., Orpana, A., Ferrara, N., Saksela, O., & Alitalo, K. (1994) · Journal of Biological Chemistry

Angiogenesis and VEGF in CancerTGF-β signaling in diseases

Cited by 694

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

Kowanetz, M., Wu, X., Lee, J., Tan, M., Hagenbeek, T., Qu, X., Yu, L., Ross, J., Korsisaari, N., Cao, T., et al. (2010) · Proceedings of the National Academy of Sciences

Chemokine receptors and signalingImmune cells in cancer

Cited by 663

An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy

Chung, A. S., Wu, X., Zhuang, G., Ngu, H., Kasman, I., Zhang, J., Vernes, J.-M., Jiang, Z., Meng, Y. G., Peale, F. V., et al. (2013) · Nature Medicine

Angiogenesis and VEGF in CancerCancer Immunotherapy and Biomarkers

Cited by 445

The hypoxic response of tumors is dependent on their microenvironment

Blouw, B., Song, H., Tihan, T., Bosze, J., Ferrara, N., Gerber, H.-P., Johnson, R. S., & Bergers, G. (2003) · Cancer Cell

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 408

A direct and melanopsin-dependent fetal light response regulates mouse eye development

Rao, S., Chun, C., Fan, J., Kofron, J. M., Yang, M. B., Hegde, R. S., Ferrara, N., Copenhagen, D. R., & Lang, R. A. (2013) · Nature

Retinal Development and DisordersRetinopathy of Prematurity Studies

Cited by 240