Tamura, Tomohiko

The IRF Family Transcription Factors in Immunity and Oncogenesis

Tamura, T., Yanai, H., Savitsky, D., & Taniguchi, T. (2008) · Annual Review of Immunology

interferon and immune responsesImmune Response and Inflammation

Cited by 1,259

IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

Masuda, T., Tsuda, M., Yoshinaga, R., Tozaki-Saitoh, H., Ozato, K., Tamura, T., & Inoue, K. (2012) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsPain Mechanisms and Treatments

Cited by 338

ICSBP Directs Bipotential Myeloid Progenitor Cells to Differentiate into Mature Macrophages

Tamura, T., Nagamura-Inoue, T., Shmeltzer, Z., Kuwata, T., & Ozato, K. (2000) · Immunity

Hematopoietic Stem Cell TransplantationImmune cells in cancer

Cited by 305

Regulation of immunity and oncogenesis by the IRF transcription factor family

Savitsky, D., Tamura, T., Yanai, H., & Taniguchi, T. (2010) · Cancer Immunology, Immunotherapy

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 298

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

Kurotaki, D., Osato, N., Nishiyama, A., Yamamoto, M., Ban, T., Sato, H., Nakabayashi, J., Umehara, M., Miyake, N., Matsumoto, N., et al. (2013) · Blood

Genomics and Chromatin DynamicsKruppel-like factors research

Cited by 252

IRF family proteins and type I interferon induction in dendritic cells

Tailor, P., Tamura, T., & Ozato, K. (2006) · Cell Research

interferon and immune responsesImmune Response and Inflammation

Cited by 186

Review: ICSBP/IRF-8: Its Regulatory Roles in the Development of Myeloid Cells

Tamura, T., & Ozato, K. (2002) · Journal of Interferon & Cytokine Research

interferon and immune responsesAcute Myeloid Leukemia Research

Cited by 183

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

Konishi, H., Okamoto, T., Hara, Y., Komine, O., Tamada, H., Maeda, M., Osako, F., Kobayashi, M., Nishiyama, A., Kataoka, Y., et al. (2020) · The EMBO Journal

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 179

Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU. 1 complex

Kanno, Y., Levi, B.-Z., Tamura, T., & Ozato, K. (2005) · Journal of Interferon & Cytokine Research

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 128

Transcription factors that regulate growth and differentiation of myeloid cells.

Nagamura-Inoue, T., Tamura, T., & Ozato, K. (2001) · International Reviews of Immunology

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 94

Gamma Interferon Triggers Interaction between ICSBP (IRF-8) and TEL, Recruiting the Histone Deacetylase HDAC3 to the Interferon-Responsive Element

Kuwata, T., Gongora, C., Kanno, Y., Sakaguchi, K., Tamura, T., Kanno, T., Basrur, V., Martinez, R., Appella, E., Golub, T., et al. (2002) · Molecular and Cellular Biology

interferon and immune responsesGenomics and Chromatin Dynamics

Cited by 69

The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15Ink4b in murine myeloid cells

Schmidt, M., Bies, J., Tamura, T., Ozato, K., & Wolff, L. (2004) · Blood

Acute Myeloid Leukemia Researchinterferon and immune responses

Cited by 58

Cooperation of PU.1 With IRF8 and NFATc1 Defines Chromatin Landscapes During RANKL-Induced Osteoclastogenesis

Izawa, N., Kurotaki, D., Nomura, S., Fujita, T., Omata, Y., Yasui, T., Hirose, J., Matsumoto, T., Saito, T., Kadono, Y., et al. (2019) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesGenomics and Chromatin Dynamics

Cited by 40

Egr2 drives the differentiation of Ly6Chi monocytes into fibrosis-promoting macrophages in metabolic dysfunction-associated steatohepatitis in mice

Iwata, A., Maruyama, J., Natsuki, S., Nishiyama, A., Tamura, T., Tanaka, M., Shichino, S., Seki, T., Komai, T., Okamura, T., et al. (2024) · Communications Biology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 25