Nishino, Seiji

The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

Lin, L., Faraco, J., Li, R., Kadotani, H., Rogers, W., Lin, X., Qiu, X., de Jong, P. J., Nishino, S., & Mignot, E. (1999) · Cell

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 2,613

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Peyron, C., Faraco, J., Rogers, W., Ripley, B., Overeem, S., Charnay, Y., Nevsimalova, S., Aldrich, M., Reynolds, D., Albin, R., et al. (2000) · Nature Medicine

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 2,118

Hypocretin (orexin) deficiency in human narcolepsy

Nishino, S., Ripley, B., Overeem, S., Lammers, G. J., & Mignot, E. (2000) · The Lancet

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 1,776

Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

Kang, J.-E., Lim, M. M., Bateman, R. J., Lee, J. J., Smyth, L. P., Cirrito, J. R., Fujiki, N., Nishino, S., & Holtzman, D. M. (2009) · Science

Alzheimer's disease research and treatmentsSleep and Wakefulness Research

Cited by 1,565

The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias

Mignot, E., Lammers, G. J., Ripley, B., Okun, M., Nevsimalova, S., Overeem, S., Vankova, J., Black, J., Harsh, J., Bassetti, C., et al. (2002) · Archives of Neurology

Sleep and Wakefulness ResearchSleep and related disorders

Cited by 1,126

Tuning arousal with optogenetic modulation of locus coeruleus neurons

Carter, M. E., Yizhar, O., Chikahisa, S., Nguyen, H., Adamantidis, A., Nishino, S., Deisseroth, K., & de Lecea, L. (2010) · Nature Neuroscience

Sleep and Wakefulness ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 993

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

Paşca, S. P., Portmann, T., Voineagu, I., Yazawa, M., Shcheglovitov, A., Paşca, A. M., Cord, B., Palmer, T. D., Chikahisa, S., Nishino, S., et al. (2011) · Nature Medicine

Pluripotent Stem Cells ResearchGenetics and Neurodevelopmental Disorders

Cited by 585

Basal forebrain circuit for sleep-wake control

Xu, M., Chung, S., Zhang, S., Zhong, P., Ma, C., Chang, W.-C., Weissbourd, B., Sakai, N., Luo, L., Nishino, S., et al. (2015) · Nature Neuroscience

Sleep and Wakefulness ResearchCircadian rhythm and melatonin

Cited by 514

Maturation and circuit integration of transplanted human cortical organoids

Revah, O., Gore, F., Kelley, K. W., Andersen, J., Sakai, N., Chen, X., Li, M.-Y., Birey, F., Yang, X., Saw, N. L., et al. (2022) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 504

CSF hypocretin/orexin levels in narcolepsy and other neurological conditions

Ripley, B., Overeem, S., Fujiki, N., Nevsimalova, S., Uchino, M., Yesavage, J., Di Monte, D., Dohi, K., Melberg, A., Lammers, G. J., et al. (2001) · Neurology

Sleep and Wakefulness ResearchSleep and related disorders

Cited by 415

Neuronal defects in a human cellular model of 22q11.2 deletion syndrome

Khan, T. A., Revah, O., Gordon, A., Yoon, S.-J., Krawisz, A. K., Goold, C., Sun, Y., Kim, C. H., Tian, Y., Li, M.-Y., et al. (2020) · Nature Medicine

Pluripotent Stem Cells ResearchGenomic variations and chromosomal abnormalities

Cited by 186

A PERIOD3 variant causes a circadian phenotype and is associated with a seasonal mood trait

Zhang, L., Hirano, A., Hsu, P.-K., Jones, C. R., Sakai, N., Okuro, M., McMahon, T., Yamazaki, M., Xu, Y., Saigoh, N., et al. (2016) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 169

CSF hypocretin-1 (orexin-A) levels in childhood narcolepsy and neurologic disorders

Arii, J., Kanbayashi, T., Tanabe, Y., Sawaishi, Y., Kimura, S., Watanabe, A., Mishima, K., Hishikawa, Y., Shimizu, T., & Nishino, S. (2004) · Neurology

Sleep and Wakefulness ResearchSleep and related disorders

Cited by 57