Johnson, F. Brad

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

Fraietta, J. A., Lacey, S. F., Orlando, E. J., Pruteanu-Malinici, I., Gohil, M., Lundh, S., Boesteanu, A. C., Wang, Y., O’Connor, R. S., Hwang, W.-T., et al. (2018) · Nature Medicine

CAR-T cell therapy researchChronic Lymphocytic Leukemia Research

Cited by 1,785

Histone H4 lysine 16 acetylation regulates cellular lifespan

Dang, W., Steffen, K. K., Perry, R., Dorsey, J. A., Johnson, F. B., Shilatifard, A., Kaeberlein, M., Kennedy, B. K., & Berger, S. L. (2009) · Nature

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 667

Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease

Nativio, R., Donahue, G., Berson, A., Lan, Y., Amlie-Wolf, A., Tuzer, F., Toledo, J. B., Gosai, S. J., Gregory, B. D., Torres, C., et al. (2018) · Nature Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 363

SLC25A51 is a mammalian mitochondrial NAD(+) transporter

Luongo, T. S., Eller, J. M., Lu, M.-J., Niere, M., Raith, F., Perry, C., Bornstein, M. R., Oliphint, P., Wang, L., McReynolds, M. R., et al. (2020) · Nature

Mitochondrial Function and PathologySirtuins and Resveratrol in Medicine

Cited by 308

DNA damage-induced type I interferon promotes senescence and inhibits stem cell function

Yu, Q., Katlinskaya, Y. V., Carbone, C. J., Zhao, B., Katlinski, K. V., Zheng, H., Guha, M., Li, N., Chen, Q., Yang, T., et al. (2015) · Cell Reports

interferon and immune responsesTelomeres, Telomerase, and Senescence

Cited by 260

Synergism in transcriptional activation: a kinetic view.

Herschlag, D., & Johnson, F. B. (1993) · Genes & Development

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 190

Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae

Smith, J. S., Chen, Q., Yatsunyk, L. A., Nicoludis, J. M., Garcia, M. S., Kranaster, R., Balasubramanian, S., Monchaud, D., Teulade-Fichou, M.-P., Abramowitz, L., et al. (2011) · Nature Structural & Molecular Biology

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 135

Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence

Crowe, E. P., Tuzer, F., Gregory, B. D., Donahue, G., Gosai, S. J., Cohen, J., Leung, Y. Y., Yetkin, E., Nativio, R., Wang, L.-S., et al. (2016) · Frontiers in Aging Neuroscience

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 110

Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response

Dang, W., Sutphin, G. L., Dorsey, J. A., Otte, G. L., Cao, K., Perry, R. M., Wanat, J. J., Saviolaki, D., Murakami, C. J., Tsuchiyama, S., et al. (2014) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsGenomics and Chromatin Dynamics

Cited by 83

Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis

Brennan, T. A., Egan, K. P., Lindborg, C. M., Chen, Q., Sweetwyne, M. T., Hankenson, K. D., Xie, S. X., Johnson, F. B., & Pignolo, R. J. (2014) · Disease Models & Mechanisms

Telomeres, Telomerase, and SenescenceBone Metabolism and Diseases

Cited by 45