Hargreaves, Iain

Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations

Pollard, P. J., Brière, J. J., Alam, N. A., Barwell, J., Barclay, E., Wortham, N. C., Hunt, T., Mitchell, M., Olpin, S., Moat, S. J., et al. (2005) · Human Molecular Genetics

Cancer, Hypoxia, and MetabolismAdrenal and Paraganglionic Tumors

Cited by 865

PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons

Wood-Kaczmar, A., Gandhi, S., Yao, Z., Abramov, A. S. Y., Miljan, E. A., Keen, G., Stanyer, L., Hargreaves, I., Klupsch, K., Deas, E., et al. (2008) · PLoS ONE

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 316

Disorders of Human Coenzyme Q10 Metabolism: An Overview

Hargreaves, I., Heaton, R. A., & Mantle, D. (2020) · International Journal of Molecular Sciences

Coenzyme Q10 studies and effectsMetabolism and Genetic Disorders

Cited by 182

Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich’s ataxia

Abeti, R., Parkinson, M. H., Hargreaves, I. P., Angelova, P. R., Sandi, C., Pook, M. A., Giunti, P., & Abramov, A. Y. (2016) · Cell Death & Disease

Mitochondrial Function and PathologyGenetic Neurodegenerative Diseases

Cited by 133

Role of Coenzyme Q10 in Health and Disease: An Update on the Last 10 Years (2010–2020)

Cirilli, I., Damiani, E., Dludla, P. V., Hargreaves, I., Marcheggiani, F., Millichap, L. E., Orlando, P., Silvestri, S., & Tiano, L. (2021) · Antioxidants

Coenzyme Q10 studies and effectsAntioxidant Activity and Oxidative Stress

Cited by 115

The Effect of HMG-CoA Reductase Inhibitors on Coenzyme Q10: Possible Biochemical/Clinical Implications

Hargreaves, I. P., Duncan, A. J., Heales, S. J. R., & Land, J. M. (2005) · Drug Safety

Coenzyme Q10 studies and effectsLipoproteins and Cardiovascular Health

Cited by 91

Mitochondrial dysfunction in the skeletal muscle of a mouse model of Rett syndrome (RTT): implications for the disease phenotype

Gold, W. A., Williamson, S. L., Kaur, S., Hargreaves, I. P., Land, J. M., Pelka, G. J., Tam, P. P. L., & Christodoulou, J. (2014) · Mitochondrion

Genetics and Neurodevelopmental DisordersMitochondrial Function and Pathology

Cited by 73

Secondary Coenzyme Q 10 Deficiencies in Oxidative Phosphorylation (OXPHOS) and Non-OXPHOS Disorders

Yubero, D., Montero, R., Martín, M. A., Montoya, J., Ribes, A., Grazina, M., Trevisson, E., Rodriguez-Aguilera, J. C., Hargreaves, I. P., Salviati, L., et al. (2016) · Mitochondrion

Coenzyme Q10 studies and effectsMitochondrial Function and Pathology

Cited by 72

Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview

Mantle, D., & Hargreaves, I. (2019) · Antioxidants

Coenzyme Q10 studies and effectsAntioxidant Activity and Oxidative Stress

Cited by 63

Coenzyme Q10 Prevents Accelerated Cardiac Aging in a Rat Model of Poor Maternal Nutrition and Accelerated Postnatal Growth

Tarry-Adkins, J. L., Blackmore, H. L., Martin-Gronert, M. S., Fernandez-Twinn, D. S., McConnell, J. M., Hargreaves, I. P., Giussani, D. A., & Ozanne, S. E. (2013) · Molecular Metabolism

Birth, Development, and HealthCoenzyme Q10 studies and effects

Cited by 47

Chronic Kidney Disease and Coenzyme Q10 Supplementation

Hargreaves, I., Mantle, D., & Milford, D. (2019) · Journal of Kidney Care

Coenzyme Q10 studies and effectsChronic Kidney Disease and Diabetes

Cited by 12