Kaplan, David R.

Regulation of neuronal survival by the serine-threonine protein kinase Akt

Dudek, H., Datta, S. R., Franke, T. F., Birnbaum, M. J., Yao, R., Cooper, G. M., Segal, R. A., Kaplan, D. R., & Greenberg, M. E. (1997) · Science

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 2,436

Neurotrophin signal transduction in the nervous system

Kaplan, D. R., & Miller, F. D. (2000) · Current Opinion in Neurobiology

Nerve injury and regenerationCell death mechanisms and regulation

Cited by 1,944

The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

Kaplan, D. R., Hempstead, B. L., Martin-Zanca, D., Chao, M. V., & Parada, L. F. (1991) · Science

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 1,379

Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB

Berkemeier, L. R., Winslow, J. W., Kaplan, D. R., Nikolics, K., Goeddel, D. V., & Rosenthal, A. (1991) · Neuron

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 836

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

Soppet, D., Escandon, E., Maragos, J., Middlemas, D. S., Raid, S. W., Blair, J., Burton, L. E., Stanton, B. R., Kaplan, D. R., Hunter, T., et al. (1991) · Cell

Nerve injury and regenerationNeurogenesis and neuroplasticity mechanisms

Cited by 820

Developmental axon pruning mediated by BDNF-p75NTR–dependent axon degeneration

Singh, K. K., Park, K. J., Hong, E. J., Kramer, B. M., Greenberg, M. E., Kaplan, D. R., & Miller, F. D. (2008) · Nature Neuroscience

Nerve injury and regenerationAxon Guidance and Neuronal Signaling

Cited by 237

Trk signaling regulates neural precursor cell proliferation and differentiation during cortical development

Bartkowska, K., Paquin, A., Gauthier, A. S., Kaplan, D. R., & Miller, F. D. (2007) · Development

Neurogenesis and neuroplasticity mechanismsNerve injury and regeneration

Cited by 226

Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma

Lun, X., Wells, J. C., Grinshtein, N., King, J. C., Hao, X., Dang, N.-H., Wang, X., Aman, A., Uehling, D., Datti, A., et al. (2016) · Clinical Cancer Research

Glioma Diagnosis and TreatmentCancer Cells and Metastasis

Cited by 197

Signaling mechanisms underlying dendrite formation

Miller, F. D., & Kaplan, D. R. (2003) · Current Opinion in Neurobiology

Neuroscience and Neuropharmacology ResearchAxon Guidance and Neuronal Signaling

Cited by 160

HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells

Pietras, A., Hansford, L. M., Johnsson, A. S., Bridges, E., Sjölund, J., Gisselsson, D., Rehn, M., Beckman, S., Noguera, R., Navarro, S., et al. (2009) · Proceedings of the National Academy of Sciences

Neuroblastoma Research and TreatmentsCancer, Hypoxia, and Metabolism

Cited by 135

Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma

Haftchenary, S., Luchman, H. A., Jouk, A. O., Veloso, A. J., Page, B. D. G., Cheng, X. R., Dawson, S. S., Grinshtein, N., Shahani, V. M., Kerman, K., et al. (2013) · ACS Medicinal Chemistry Letters

Glioma Diagnosis and TreatmentCytokine Signaling Pathways and Interactions

Cited by 126

Peripheral nerve Single-cell analysis identifies Mesenchymal Ligands that promote axonal growth

Toma, J. S., Karamboulas, K., Carr, M. J., Kolaj, A., Yuzwa, S. A., Mahmud, N., Storer, M. A., Kaplan, D. R., & Miller, F. D. (2020) · eneuro

Nerve injury and regenerationAxon Guidance and Neuronal Signaling

Cited by 82

Restoration of hippocampal neural precursor function by ablation of senescent cells in the aging stem cell niche

Fatt, M. P., Tran, L. M., Vetere, G., Storer, M. A., Simonetta, J. V., Miller, F. D., Frankland, P. W., & Kaplan, D. R. (2022) · Stem Cell Reports

Neurogenesis and neuroplasticity mechanismsTelomeres, Telomerase, and Senescence

Cited by 58

PI-3 Kinase and IP3: Partners in NT3-Induced Synaptic Transmission

Kaplan, D. R., & Cooper, E. (2001) · Nature Neuroscience

Nerve injury and regenerationNeuroscience and Neuropharmacology Research

Cited by 20