Cardon, Lon R.

Finding the missing heritability of complex diseases

Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., McCarthy, M. I., Ramos, E. M., Cardon, L. R., Chakravarti, A., et al. (2009) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 8,336

A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

Frayling, T. M., Timpson, N. J., Weedon, M. N., Zeggini, E., Freathy, R. M., Lindgren, C. M., Perry, J. R. B., Elliott, K. S., Lango, H., Rayner, N. W., et al. (2007) · Science

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 4,531

Methodology for Genetic Studies of Twins and Families

Neale, M. C., & Cardon, L. R. (1992) · Springer eBooks

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 4,005

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

McCarthy, M. I., Abecasis, G. R., Cardon, L. R., Goldstein, D. B., Little, J., Ioannidis, J. P. A., & Hirschhorn, J. N. (2008) · Nature Reviews Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,891

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

the NIDDK IBD Genetics Consortium, Barrett, J. C., the Belgian-French IBD Consortium, the Wellcome Trust Case Control Consortium, Hansoul, S., Nicolae, D. L., Cho, J. H., Duerr, R. H., Rioux, J. D., Brant, S. R., et al. (2008) · Nature Genetics

Inflammatory Bowel DiseaseGenetic Associations and Epidemiology

Cited by 2,593

Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes

Zeggini, E., Weedon, M. N., Lindgren, C. M., Frayling, T. M., Elliott, K. S., Lango, H., Timpson, N. J., Perry, J. R. B., Rayner, N. W., Freathy, R. M., et al. (2007) · Science

Genetic Associations and EpidemiologyDiabetes and associated disorders

Cited by 2,194

The support of human genetic evidence for approved drug indications

Nelson, M. R., Tipney, H., Painter, J. L., Shen, J., Nicoletti, P., Shen, Y., Floratos, A., Sham, P. C., Li, M. J., Wang, J., et al. (2015) · Nature Genetics

Genetic Associations and EpidemiologyComputational Drug Discovery Methods

Cited by 1,666

Replicating genotype–phenotype associations

NCI-NHGRI Working Group on Replication in Association Studies, Chanock, S. J., Manolio, T., Boehnke, M., Boerwinkle, E., Hunter, D. J., Thomas, G., Hirschhorn, J. N., Abecasis, G., Altshuler, D., et al. (2007) · Nature

Genetic Associations and EpidemiologyMeta-analysis and systematic reviews

Cited by 1,352

Data quality control in genetic case-control association studies

Anderson, C. A., Pettersson, F. H., Clarke, G. M., Cardon, L. R., Morris, A. P., & Zondervan, K. T. (2010) · Nature Protocols

Genetic Associations and EpidemiologyGenetic diversity and population structure

Cited by 1,318

A General Test of Association for Quantitative Traits in Nuclear Families

Abecasis, G. R., Cardon, L. R., & Cookson, W. O. C. (2000) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,126

The effects of human population structure on large genetic association studies

Marchini, J., Cardon, L. R., Phillips, M. S., & Donnelly, P. (2004) · Nature Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 869

An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28

Owen, D. R., Yeo, A. J., Gunn, R. N., Song, K., Wadsworth, G., Lewis, A., Rhodes, C., Pulford, D. J., Bennacef, I., Parker, C. A., et al. (2012) · Journal of Cerebral Blood Flow & Metabolism

Neuroinflammation and Neurodegeneration MechanismsPharmacological Receptor Mechanisms and Effects

Cited by 779

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people

Nelson, M. R., Wegmann, D., Ehm, M. G., Kessner, D., St. Jean, P., Verzilli, C., Shen, J., Tang, Z., Bacanu, S.-A., Fraser, D., et al. (2012) · Science

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 647

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

Van Hout, C. V., Tachmazidou, I., Backman, J. D., Hoffman, J. D., Liu, D., Pandey, A. K., Gonzaga-Jauregui, C., Khalid, S., Ye, B., Banerjee, N., et al. (2020) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 561

Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease

Waterworth, D. M., Ricketts, S. L., Song, K., Chen, L., Zhao, J. H., Ripatti, S., Aulchenko, Y. S., Zhang, W., Yuan, X., Lim, N., et al. (2010) · Arteriosclerosis, Thrombosis, and Vascular Biology

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 405

Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots

Phillips, M. S., Lawrence, R., Sachidanandam, R., Morris, A. P., Balding, D. J., Donaldson, M. A., Studebaker, J. F., Ankener, W. M., Alfisi, S. V., Kuo, F.-S., et al. (2003) · Nature Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 278

What makes a good case–control study?

Zondervan, K. T., Cardon, L. R., & Kennedy, S. H. (2002) · Human Reproduction

Endometriosis Research and TreatmentStatistical Methods in Epidemiology

Cited by 271

Pervasive CpG suppression in animal mitochondrial genomes

Cardon, L. R., Burge, C., Clayton, D. A., & Karlin, S. (1994) · Proceedings of the National Academy of Sciences

Genomics and Phylogenetic StudiesFractal and DNA sequence analysis

Cited by 238

Whole exome sequencing and characterization of coding variation in 49,960 individuals in the UK Biobank

Van Hout, C. V., Tachmazidou, I., Backman, J. D., Hoffman, J. X., Ye, B., Pandey, A. K., Gonzaga-Jauregui, C., Khalid, S., Liu, D., Banerjee, N., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 110

Genetic etiology of comorbid reading difficulties and ADHD

Willcutt, E. G., DeFries, J. C., Pennington, B. F., Smith, S. D., Cardon, L. R., & Olson, R. K. (2003) · Behavioral genetics in the postgenomic era.

Attention Deficit Hyperactivity DisorderReading and Literacy Development

Cited by 54

Identifying therapeutic drug targets using bidirectional effect genes

Estrada, K., Froelich, S., Wuster, A., Bauer, C. R., Sterling, T., Clark, W. T., Ru, Y., Trinidad, M., Nguyen, H. P., Luu, A. R., et al. (2021) · Nature Communications

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 25