Howson, Joanna M. M.

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

Ueda, H., Howson, J. M. M., Esposito, L., Heward, J., Snook, Chamberlain, G., Rainbow, D. B., Hunter, K. M. D., Smith, A. N., Di Genova, G., et al. (2003) · Nature

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 2,175

Plasma proteomic associations with genetics and health in the UK Biobank

Sun, B. B., Chiou, J., Traylor, M., Benner, C., Hsu, Y.-H., Richardson, T. G., Surendran, P., Mahajan, A., Robins, C., Vasquez-Grinnell, S. G., et al. (2023) · Nature

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 1,880

Genetic regulation of the human plasma proteome in 54,306 UK Biobank participants

Sun, B. B., Chiou, J., Traylor, M., Benner, C., Hsu, Y.-H., Richardson, T. G., Surendran, P., Mahajan, A., Robins, C., Vasquez-Grinnell, S. G., et al. (2022) · Nature

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 1,833

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

Finland, G. O. T. 1. D. I., Todd, J. A., the Wellcome Trust Case Control Consortium, Walker, N. M., Cooper, J. D., Smyth, D. J., Downes, K., Plagnol, V., Bailey, R., Nejentsev, S., et al. (2007) · Nature Genetics

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 1,456

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Program, T. M. V., Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 1,381

The genetic architecture of type 2 diabetes

Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., et al. (2016) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,051

Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis

Burgess, S., Ference, B. A., Staley, J. R., Freitag, D. F., Mason, A. M., Nielsen, S. F., Willeit, P., Young, R., Surendran, P., Karthikeyan, S., et al. (2018) · JAMA Cardiology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 689

A robust and efficient method for Mendelian randomization with hundreds of genetic variants

Burgess, S., Foley, C. N., Allara, E., Staley, J. R., & Howson, J. M. M. (2020) · Nature Communications

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 681

The Polygenic and Monogenic Basis of Blood Traits and Diseases

Vuckovic, D., Bao, E. L., Akbari, P., Lareau, C. A., Mousas, A., Jiang, T., Chen, M.-H., Raffield, L. M., Tardaguila, M., Huffman, J. E., et al. (2020) · Cell

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 671

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

Chen, M.-H., Raffield, L. M., Mousas, A., Sakaue, S., Huffman, J. E., Moscati, A., Trivedi, B., Jiang, T., Akbari, P., Vuckovic, D., et al. (2020) · Cell

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 661

Rare and low-frequency coding variants alter human adult height

Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., et al. (2017) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 610

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

Zanoni, P., Khetarpal, S. A., Larach, D. B., Hancock-Cerutti, W. F., Millar, J. S., Cuchel, M., DerOhannessian, S., Kontush, A., Surendran, P., Saleheen, D., et al. (2016) · Science

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 545

Population structure, differential bias and genomic control in a large-scale, case-control association study

Clayton, D. G., Walker, N. M., Smyth, D. J., Pask, R., Cooper, J. D., Maier, L. M., Smink, L. J., Lam, A. C., Ovington, N. R., Stevens, H. E., et al. (2005) · Nature Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 526

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 442

Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases

Ferreira, R. C., Freitag, D. F., Cutler, A. J., Howson, J. M. M., Rainbow, D. B., Smyth, D. J., Kaptoge, S., Clarke, P., Boreham, C., Coulson, R. M., et al. (2013) · PLoS Genetics

Cytokine Signaling Pathways and InteractionsGenetic Associations and Epidemiology

Cited by 316

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

CHARGE-Heart Failure Consortium, Surendran, P., EchoGen Consortium, METASTROKE Consortium, GIANT Consortium, EPIC-InterAct Consortium, Study, L. C., Wellcome Trust Case Control Consortium, Understanding Society Scientific Group, EPIC-CVD Consortium, et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 312

Interleukin‐10, Polymorphism in SLC11A1(formerly NRAMP1), and Susceptibility to Tuberculosis

Awomoyi, A. A., Marchant, A., Howson, J. M. M., McAdam, K. P. W. J., Blackwell, J. M., & Newport, M. J. (2002) · The Journal of Infectious Diseases

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 153

Genetic Analysis of Adult-Onset Autoimmune Diabetes

Howson, J. M. M., Rosinger, S., Smyth, D. J., Boehm, B. O., the ADBW-END Study Group, & Todd, J. A. (2011) · Diabetes

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 143

Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases

Cai, N., Gomez-Duran, A., Yonova-Doing, E., Kundu, K., Burgess, A. I., Golder, Z. J., Calabrese, C., Bonder, M. J., Camacho, M., Lawson, R. A., et al. (2021) · Nature Medicine

Mitochondrial Function and PathologyGenetic Associations and Epidemiology

Cited by 73

A comparison of Cox and logistic regression for use in genome-wide association studies of cohort and case-cohort design

on behalf of the EPIC-CVD Consortium, Staley, J. R., Jones, E., Kaptoge, S., Butterworth, A. S., Sweeting, M. J., Wood, A. M., & Howson, J. M. M. (2017) · European Journal of Human Genetics

Genetic Associations and EpidemiologyStatistical Methods in Epidemiology

Cited by 58

Leveraging human genetic data to investigate the cardiometabolic effects of glucose-dependent insulinotropic polypeptide signalling

Karhunen, V., Daghlas, I., Zuber, V., Vujkovic, M., Olsen, A. K., Knudsen, L. B., Haynes, W. G., Howson, J. M. M., & Gill, D. (2021) · Diabetologia

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

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