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Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system

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Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT

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Monocyte, neutrophil, and whole blood transcriptome dynamics following ischemic stroke

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Genome-wide association studies of COVID-19: Connecting the dots

Ferreira, L. C., Gomes, C. E. M., Rodrigues-Neto, J. F., & Jerônimo, S. M. B. (2022) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2022.105379 · Cited by 40 · see citing works

CYP2C19 Genotype Prevalence and Association With Recurrent Myocardial Infarction in British–South Asians Treated With Clopidogrel

Magavern, E. F., Jacobs, B. M., Warren, H. R., Finocchiaro, G., Finer, S., van Heel, D. A., Smedley, D. P., & Caulfield, M. J. (2023) · JACC Advances · doi:10.1016/j.jacadv.2023.100573 · Cited by 39 · see citing works

Cross-ancestry genome-wide association studies of brain imaging phenotypes

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PGS-server: accuracy, robustness and transferability of polygenic score methods for biobank scale studies

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Genetic determinants of cardiometabolic and pulmonary phenotypes and obstructive sleep apnoea in HCHS/SOL

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SCAPE: a mixture model revealing single-cell polyadenylation diversity and cellular dynamics during cell differentiation and reprogramming

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Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes

Liu, N., Zhang, L. J., Tian, T., Cheng, J., Zhang, B., Qiu, S., Geng, Z., Cui, G., Zhang, Q., Liao, W., et al. (2023) · Nature Genetics · doi:10.1038/s41588-023-01425-8 · Cited by 39 · see citing works

Genome-wide association study of hospitalized COVID-19 patients in the United Arab Emirates

Mousa, M., Vurivi, H., Kannout, H., Uddin, M., Kaabi, N. A., Mahboub, B. H., Tay, G. K., & AlSafar, H. S. (2021) · EBioMedicine · doi:10.1016/j.ebiom.2021.103695 · Cited by 36 · see citing works

A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology

Akbari, P., Vuckovic, D., Stefanucci, L., Jiang, T., Kundu, K., Kreuzhuber, R., Bao, E. L., Collins, J., Downes, K., Grassi, L., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-40679-y · Cited by 35 · see citing works

Proteome-wide Systems Genetics to Identify Functional Regulators of Complex Traits

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Aggregating multiple expression prediction models improves the power of transcriptome-wide association studies

Zeng, P., Dai, J., Jin, S., & Zhou, X. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddab056 · Cited by 35 · see citing works

Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with global and local ancestries

Natri, H. M., Hudjashov, G., Jacobs, G., Kusuma, P., Saag, L., Darusallam, C. C., Metspalu, M., Sudoyo, H., Cox, M. P., Gallego Romero, I., et al. (2022) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2021.11.017 · Cited by 33 · see citing works

Gamma-glutamyl-leucine levels are causally associated with elevated cardio-metabolic risks

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Beyond GWAS: from simple associations to functional insights

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Correlations between complex human phenotypes vary by genetic background, gender, and environment

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Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism

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Heterogeneity in Hematological Parameters of High and Low Altitude Tibetan Populations

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Unraveling Risk Genes of COVID-19 by Multi-Omics Integrative Analyses

Baranova, A. V., Cao, H., & Zhang, F. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.738687 · Cited by 32 · see citing works

Disentangling Signatures of Selection Before and After European Colonization in Latin Americans

Mendoza‐Revilla, J., Chacón-Duque, J. C., Fuentes‐Guajardo, M., Ormond, L., Wang, K., Hurtado, M., Villegas, V., Granja, V., Acuña-Alonzo, V., Jaramillo, C., et al. (2022) · Molecular Biology and Evolution · doi:10.1093/molbev/msac076 · Cited by 33 · see citing works

Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis

Han, Y., Byun, J., Zhu, C., Sun, R., Roh, J. Y., Cordell, H. J., Lee, H., Shaw, V. R., Kang, S. W., Razjouyan, J., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36678-8 · Cited by 30 · see citing works

SVEP1 is an endogenous ligand for the orphan receptor PEAR1

Elenbaas, J. S., Pudupakkam, U., Ashworth, K. J., Kang, C. J., Patel, V., Santana, K., Jung, I., Lee, P. C., Burks, K. H., Amrute, J., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36486-0 · Cited by 30 · see citing works

IL6 genetic perturbation mimicking IL-6 inhibition is associated with lower cardiometabolic risk

Zhang, L., Omarov, M., Xu, L., deGoma, E. M., Natarajan, P., & Georgakis, M. K. (2025) · Nature Cardiovascular Research · doi:10.1038/s44161-025-00700-7 · Cited by 30 · see citing works

Epidemiological and genetic overlap among biological aging clocks: New challenges in biogerontology

Gialluisi, A., Santoro, A., Tirozzi, A., Cerletti, C., Donati, M. B., de Gaetano, G., Franceschi, C., & Iacoviello, L. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101502 · Cited by 29 · see citing works

Towards a global view of multiple sclerosis genetics

Jacobs, B. M., Peter, M., Giovannoni, G., Noyce, A. J., Morris, H. R., & Dobson, R. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-022-00704-y · Cited by 28 · see citing works

Human immune system: Exploring diversity across individuals and populations

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A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans

Moksnes, M. R., Hansen, A. F., Wolford, B. N., Thomas, L. F., Rasheed, H., Simić, A., Bhatta, L., Brantsæter, A. L., Surakka, I. L., Zhou, W., et al. (2024) · Communications Biology · doi:10.1038/s42003-024-06101-z · Cited by 30 · see citing works

Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites

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CNest: A novel copy number association discovery method uncovers 862 new associations from 200,629 whole-exome sequence datasets in the UK Biobank

Fitzgerald, T. W., & Birney, E. (2022) · Cell Genomics · doi:10.1016/j.xgen.2022.100167 · Cited by 26 · see citing works

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program

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Exploring the association and causal effect between white blood cells and psoriasis using large-scale population data

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SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease

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DNA binding analysis of rare variants in homeodomains reveals homeodomain specificity-determining residues

Kock, K. H., Kimes, P. K., Gisselbrecht, S. S., Inukai, S., Phanor, S. K., Anderson, J. T., Ramakrishnan, G., Lipper, C. H., Song, D., Kurland, J. V., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-47396-0 · Cited by 24 · see citing works

An allelic-series rare-variant association test for candidate-gene discovery

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Trans-ethnic meta-analysis of white blood cell phenotypes

Keller, M. F., Reiner, A. P., Okada, Y., van Rooij, F. J. A., Johnson, A. D., Chen, M., Smith, A. V., Morris, A. P., Tanaka, T., Ferrucci, L., et al. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddu401 · Cited by 73 · see citing works

Understanding ancestry-specific disease allelic effect sizes by leveraging multi-ancestry single-cell RNA-seq data

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Genetic architecture of routinely acquired blood tests in a British South Asian cohort

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Transcriptome-Wide Association Study of Blood Cell Traits in African Ancestry and Hispanic/Latino Populations

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Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study

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