Beaumont, Carole

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 ( USF2 ) knockout mice

Nicolas, G., Bennoun, M., Devaux, I., Beaumont, C., Grandchamp, B., Kahn, A., & Vaulont, S. (2001) · Proceedings of the National Academy of Sciences

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 1,233

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

Nicolas, G., Chauvet, C., Viatte, L., Danan, J. L., Bigard, X., Devaux, I., Beaumont, C., Kahn, A., & Vaulont, S. (2002) · Journal of Clinical Investigation

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 1,214

Severe iron deficiency anemia in transgenic mice expressing liver hepcidin

Nicolas, G., Bennoun, M., Porteu, A., Mativet, S., Beaumont, C., Grandchamp, B., Sirito, M., Sawadogo, M., Kahn, A., & Vaulont, S. (2002) · Proceedings of the National Academy of Sciences

Iron Metabolism and DisordersTrace Elements in Health

Cited by 880

Ferritin heavy chain upregulation by NF-κB inhibits TNFα-induced apoptosis by suppressing reactive oxygen species

Pham, C. G., Bubici, C., Zazzeroni, F., Papa, S., Jones, J., Alvarez, K., Jayawardena, S., De Smaele, E., Cong, R., Beaumont, C., et al. (2004) · Cell

NF-κB Signaling PathwaysCell death mechanisms and regulation

Cited by 663

Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis

Nicolas, G., Viatte, L., Lou, D.-Q., Bennoun, M., Beaumont, C., Kahn, A., Andrews, N. C., & Vaulont, S. (2003) · Nature Genetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 311

Mutation in the iron responsive element of the L ferritin mRNA in a family with dominant hyperferritinaemia and cataract

Beaumont, C., Leneuve, P., Devaux, I., Scoazec, J.-Y., Berthier, M., Loiseau, M.-N., Grandchamp, B., & Bonneau, D. (1995) · Nature Genetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 293

Presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and down-regulated by hepcidin

Delaby, C., Pilard, N., Gonçalves, A. S., Beaumont, C., & Canonne-Hergaux, F. (2005) · Blood

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 283

Intestinal DMT1 cotransporter is down-regulated by hepcidin via proteasome internalization and degradation

Brasse–Lagnel, C., Karim, Z., Letteron, P., Bekri, S., Bado, A., & Beaumont, C. (2011) · Gastroenterology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 230

Neuromelanin associated redox-active iron is increased in the substantia nigra of patients with Parkinson's disease

Faucheux, B. A., Martin, M., Beaumont, C., Hauw, J., Agid, Y., & Hirsch, E. C. (2003) · Journal of Neurochemistry

Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolism

Cited by 229

H-ferritin subunit overexpression in erythroid cells reduces the oxidative stress response and induces multidrug resistance properties

Epsztejn, S., Glickstein, H., Picard, V., Slotki, I. N., Breuer, W., Beaumont, C., & Cabantchik, Z. I. (1999) · Blood

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 209

Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

Callens, C., Coulon, S., Naudin, J., Radford-Weiss, I., Boissel, N., Raffoux, E., Wang, P. H. M., Agarwal, S., Tamouza, H., Paubelle, E., et al. (2010) · Journal of Experimental Medicine

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 197

Role for NF-κB in the regulation of ferritin H by tumor necrosis factor-α

Kwak, E. L., Larochelle, D. A., Beaumont, C., Torti, S. V., & Torti, F. M. (1995) · Journal of Biological Chemistry

Iron Metabolism and DisordersNF-κB Signaling Pathways

Cited by 189

Lack of up-regulation of ferritin is associated with sustained iron regulatory protein-1 binding activity in the substantia nigra of patients with Parkinson's disease

Faucheux, B. A., Martin, M., Beaumont, C., Hunot, S., Hauw, J., Agid, Y., & Hirsch, E. C. (2002) · Journal of Neurochemistry

Iron Metabolism and DisordersParkinson's Disease Mechanisms and Treatments

Cited by 116

A physiological model to study iron recycling in macrophages

Delaby, C., Pilard, N., Hetet, G., Driss, F., Grandchamp, B., Beaumont, C., & Canonne-Hergaux, F. (2005) · Experimental Cell Research

Iron Metabolism and DisordersHeme Oxygenase-1 and Carbon Monoxide

Cited by 103

Analysis of Ferritins in Lymphoblastoid Cell Lines and in the Lens of Subjects With Hereditary Hyperferritinemia-Cataract Syndrome

Levi, S., Girelli, D., Perrone, F., Pasti, M., Beaumont, C., Corrocher, R., Albertini, A., & Arosio, P. (1998) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 96

Multiple regulatory mechanisms act in concert to control ferroportin expression and heme iron recycling by macrophages

Beaumont, C. (2010) · Haematologica

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 37

Mouse ferritin H subunit gene. Functional analysis of the promoter and identification of an upstream regulatory element active in erythroid cells.

Beaumont, C., Seyhan, A., Yachou, A. K., Grandchamp, B., & Jones, R. (1994) · Journal of Biological Chemistry

Iron Metabolism and DisordersGenomics and Chromatin Dynamics

Cited by 33