Ferritin heavy chain upregulation by NF-κB inhibits TNFα-induced apoptosis by suppressing reactive oxygen species

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

Ghosh, S., May, M. J., & Kopp, E. B. (1998) · Annual Review of Immunology · doi:10.1146/annurev.immunol.16.1.225 · Cited by 5,182 · see citing works

Mammalian MAP kinase signalling cascades

Chang, L., & Karin, M. (2001) · Nature · doi:10.1038/35065000 · Cited by 5,118 · see citing works

Cell Death

Danial, N. N., & Korsmeyer, S. J. (2004) · Cell · doi:10.1016/s0092-8674(04)00046-7 · Cited by 4,651 · see citing works

Signal transduction by the JNK group of MAP kinases

Davis, R. J. (2000) · Cell · doi:10.1016/s0092-8674(00)00116-1 · Cited by 4,237 · see citing works

Four deaths and a funeral: from caspases to alternative mechanisms

Leist, M., & Jäättelä, M. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35085008 · Cited by 1,585 · see citing works

Regulation of ferritin genes and protein

Torti, F. M., & Torti, S. V. (2002) · Blood · doi:10.1182/blood.v99.10.3505 · Cited by 1,173 · see citing works

Mitochondrial reactive oxygen species in cell death signaling

Fleury, C., Mignotte, B., & Vayssière, J. (2002) · Biochimie · doi:10.1016/s0300-9084(02)01369-x · Cited by 1,069 · see citing works

Carbon Monoxide Generated by Heme Oxygenase 1 Suppresses Endothelial Cell Apoptosis

Brouard, S., Otterbein, L. E., Anrather, J., Tobiasch, E., Bach, F. H., Choi, A. M. K., & Soares, M. P. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.7.1015 · Cited by 984 · see citing works

To be, or not to be: NF-κB is the answer – role of Rel/NF-κB in the regulation of apoptosis

Kucharczak, J., Simmons, M. J., Fan, Y., & Gélinas, C. (2003) · Oncogene · doi:10.1038/sj.onc.1207230 · Cited by 761 · see citing works

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosisPreprint

Zong, W.-X., Edelstein, L., Chen, C.-L., Bash, J., & Gélinas, C. (1999) · Genes & Development · doi:10.1101/gad.13.4.382 · Cited by 738 · see citing works

Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signalling

De Smaele, E., Zazzeroni, F., Papa, S., Nguyen, D. U., Jin, R., Jones, J., Cong, R., & Franzoso, G. (2001) · Nature · doi:10.1038/35104560 · Cited by 732 · see citing works

Inhibition of JNK activation through NF-κB target genes

Tang, G., Minemoto, Y., Dibling, B., Purcell, N. H., Li, Z., Karin, M., & Lin, A. (2001) · Nature · doi:10.1038/35104568 · Cited by 721 · see citing works

ROS, stress‐activated kinases and stress signaling in cancer

Benhar, M., Engelberg, D., & Levitzki, A. (2002) · The EMBO Reports · doi:10.1093/embo-reports/kvf094 · Cited by 600 · see citing works

Regulation and measurement of oxidative stress in apoptosis

Curtin, J. F., Donovan, M., & Cotter, T. G. (2002) · Journal of Immunological Methods · doi:10.1016/s0022-1759(02)00070-4 · Cited by 581 · see citing works

A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis

Deng, Y., Ren, X., Yang, L., Lin, Y., & Wu, X. (2003) · Cell · doi:10.1016/s0092-8674(03)00757-8 · Cited by 553 · see citing works

NF-κB as a therapeutic target in cancer

Orlowski, R. Z., & Baldwin, A. S. (2002) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(02)02375-4 · Cited by 552 · see citing works

Ferritin, iron homeostasis, and oxidative damage1,2 1Guest Editor: Mario Comporti 2This article is part of a series of reviews on “Iron and Cellular Redox Status.” The full list of papers may be found on the homepage of the journal.

Arosio, P., & Levi, S. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00842-0 · Cited by 543 · see citing works

NF‐κB inhibits TNF‐induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death

Sakon, S., Xue, X., Takekawa, M., Sasazuki, T., Okazaki, T., Kojima, Y., Piao, J., Yagita, H., Okumura, K., Doi, T., et al. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg379 · Cited by 497 · see citing works

Interfering with Apoptosis: Ca 2+ -Binding Protein ALG-2 and Alzheimer's Disease Gene ALG-3

Vito, P., Lacaná, E., & D'adamio, L. (1996) · Science · doi:10.1126/science.271.5248.521 · Cited by 468 · see citing works

Gadd45β mediates the NF-κB suppression of JNK signalling by targeting MKK7/JNKK2

Papa, S., Zazzeroni, F., Bubici, C., Jayawardena, S., Alvarez, K., Matsuda, S., Nguyen, D. U., Pham, C. G., Nelsbach, A. H., Melis, T., et al. (2004) · Nature Cell Biology · doi:10.1038/ncb1093 · Cited by 321 · see citing works

Heme Oxygenase-1-derived Carbon Monoxide Requires the Activation of Transcription Factor NF-κB to Protect Endothelial Cells from Tumor Necrosis Factor-α-mediated Apoptosis

Brouard, S., Berberat, P. O., Tobiasch, E., Seldon, M. P., Bach, F. H., & Soares, M. P. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m108317200 · Cited by 306 · see citing works

E2F1 and c-Myc Potentiate Apoptosis through Inhibition of NF-κB Activity that Facilitates MnSOD-Mediated ROS Elimination

Tanaka, H., Matsumura, I., Ezoe, S., Satoh, Y., Sakamaki, T., Albanese, C., Machii, T., Pestell, R. G., & Kanakura, Y. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00522-1 · Cited by 289 · see citing works

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

Maeda, S., Chang, L., Li, Z.-W., Luo, J.-L., Leffert, H., & Karin, M. (2003) · Immunity · doi:10.1016/s1074-7613(03)00301-7 · Cited by 286 · see citing works

Pathogenesis and treatment of anaemia of chronic disease

Weiß, G. (2002) · Blood Reviews · doi:10.1054/blre.2002.0193 · Cited by 276 · see citing works

Early Embryonic Lethality of H Ferritin Gene Deletion in Mice

Ferreira, C., Bucchini, D., Martin, M.-E., Levi, S., Arosio, P., Grandchamp, B., & Beaumont, C. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.5.3021 · Cited by 275 · see citing works

Physiological Roles of ASK1-Mediated Signal Transduction in Oxidative Stress- and Endoplasmic Reticulum Stress-Induced Apoptosis: Advanced Findings from ASK1 Knockout Mice

Matsuzawa, A., Nishitoh, H., Tobiume, K., Takeda, K., & Ichijo, H. (2002) · Antioxidants and Redox Signaling · doi:10.1089/15230860260196218 · Cited by 249 · see citing works

Reactive oxygen intermediates in TNF signaling

Garg, A. K., & Aggarwal, B. B. (2002) · Molecular Immunology · doi:10.1016/s0161-5890(02)00207-9 · Cited by 227 · see citing works

Reactive oxygen species are downstream products of TRAF-mediated signal transduction

Chandel, N. S., Schumacker, P. T., & Arch, R. H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103074200 · Cited by 203 · see citing works

Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin

Cozzi, A., Corsi, B., Levi, S., Santambrogio, P., Biasiotto, G., & Arosio, P. (2004) · Blood · doi:10.1182/blood-2003-06-1842 · Cited by 132 · see citing works

NF-κB activation results in rapid inactivation of JNK in TNFα-treated Ewing sarcoma cells: a mechanism for the anti-apoptotic effect of NF-κB

Javelaud, D., & Besançon, F. (2001) · Oncogene · doi:10.1038/sj.onc.1204570 · Cited by 124 · see citing works

NF-κB-dependent MnSOD expression protects adenocarcinoma cells from TNF-α-induced apoptosis

Delhalle, S., Deregowski, V., Benoît, V., Merville, M., & Bours, V. (2002) · Oncogene · doi:10.1038/sj.onc.1205489 · Cited by 111 · see citing works

Repression of ferritin expression increases the labile iron pool, oxidative stress, and short-term growth of human erythroleukemia cells

Kakhlon, O., Gruenbaum, Y., & Cabantchik, Z. I. (2001) · Blood · doi:10.1182/blood.v97.9.2863 · Cited by 97 · see citing works

Role of iron and ferritin in TNFα‐induced apoptosis in HeLa cells

Cozzi, A., Levi, S., Corsi, B., Santambrogio, P., Campanella, A., Gerardi, G., & Arosio, P. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00114-5 · Cited by 76 · see citing works

Antiproliferative and antiapoptotic effects of crel may occur within the same cells via the up-regulation of manganese superoxide dismutase.

Bernard, D., Quatannens, B., Begue, A., Vandenbunder, B., & Abbadie, C. (2001) · PubMed · Cited by 72 · see citing works

Role of the Intronic Enhancer in Tumor Necrosis Factor-mediated Induction of Manganous Superoxide Dismutase

Guo, Z., Boekhoudt, G. H., & Boss, J. M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303431200 · Cited by 70 · see citing works

Effects of TNF-α and IL-1β on iron metabolism by A549 cells and influence on cytotoxicity

Smirnov, I. M., Bailey, K., Flowers, C. H., Garrigues, N. W., & Wesselius, L. (1999) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1999.277.2.l257 · Cited by 59 · see citing works

The role of Rel/NF-κB transcription factors in B lymphocyte survival

Gerondakis, S., & Strasser, A. (2003) · Seminars in Immunology · doi:10.1016/s1044-5323(03)00036-8 · Cited by 58 · see citing works

Deferoxamine reduces tissue injury and lethality in LPS-treated mice

Vulcano, M., Meiss, R. P., & Isturiz, M. A. (2000) · International Journal of Immunopharmacology · doi:10.1016/s0192-0561(00)00026-6 · Cited by 48 · see citing works

Antisense ferritin oligonucleotides inhibit growth and induce apoptosis in human breast carcinoma cells.

Yang, D. C., Jiang, X., Elliott, R. L., et al. (2002) · PubMed · Cited by 24 · see citing works

Oxidative stress, inflammation, and cancer: How are they linked?

Reuter, S., Gupta, S. C., Chaturvedi, M. M., & Aggarwal, B. B. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.09.006 · Cited by 5,441 · see citing works

Nuclear factor-κB in cancer development and progression

Karin, M. (2006) · Nature · doi:10.1038/nature04870 · Cited by 3,519 · see citing works

Crosstalk of reactive oxygen species and NF-κB signaling

Morgan, M. J., & Liu, Z.-G. (2011) · Cell Research · doi:10.1038/cr.2010.178 · Cited by 3,505 · see citing works

Iron and cancer: more ore to be mined

Torti, S. V., & Torti, F. M. (2013) · Nature Reviews Cancer · doi:10.1038/nrc3495 · Cited by 1,621 · see citing works

Mechanisms of Cell Protection by Heme Oxygenase-1

Gozzelino, R., Jeney, V., & Soares, M. P. (2010) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.010909.105600 · Cited by 1,241 · see citing works

NF-κB in oxidative stress

Lingappan, K. (2018) · Current Opinion in Toxicology · doi:10.1016/j.cotox.2017.11.002 · Cited by 1,051 · see citing works

TNF and ROS crosstalk in inflammation

Blaser, H., Dostert, C., Mak, T. W., & Brenner, D. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.12.002 · Cited by 1,008 · see citing works

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

Hamanaka, R. B., & Chandel, N. S. (2010) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2010.04.002 · Cited by 1,011 · see citing works

Circuitry of nuclear factor κB signaling

Hoffmann, A., & Baltimore, D. (2006) · Immunological Reviews · doi:10.1111/j.0105-2896.2006.00375.x · Cited by 907 · see citing works

Ferritins: A family of molecules for iron storage, antioxidation and more

Arosio, P., Ingrassia, R., & Cavadini, P. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2008.09.004 · Cited by 886 · see citing works

The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover

Chang, L., Kamata, H., Solinas, G., Luo, J.-L., Maeda, S., Venuprasad, K., Liu, Y.-C., & Karin, M. (2006) · Cell · doi:10.1016/j.cell.2006.01.021 · Cited by 706 · see citing works

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

Kell, D. B. (2009) · BMC Medical Genomics · doi:10.1186/1755-8794-2-2 · Cited by 554 · see citing works

Hyperferritinemia and inflammation

Kernan, K. F., & Carcillo, J. A. (2017) · International Immunology · doi:10.1093/intimm/dxx031 · Cited by 638 · see citing works

The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis

Duran, A., Linares, J. F., Galvez, A. S., Wikenheiser, K., Flores, J. M., Diaz-Meco, M. T., & Moscat, J. (2008) · Cancer Cell · doi:10.1016/j.ccr.2008.02.001 · Cited by 541 · see citing works

Intracellular iron transport and storage: from molecular mechanisms to health implications

Mackenzie, E. L., Iwasaki, K., & Tsuji, Y. (2008) · Antioxidants & Redox Signaling · doi:10.1089/ars.2007.1893 · Cited by 526 · see citing works

Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis

Sakurai, T., He, G., Matsuzawa, A., Yu, G.-Y., Maeda, S., Hardiman, G., & Karin, M. (2008) · Cancer Cell · doi:10.1016/j.ccr.2008.06.016 · Cited by 487 · see citing works

Macrophages and Iron Metabolism

Soares, M. P., & Hamza, I. (2016) · Immunity · doi:10.1016/j.immuni.2016.02.016 · Cited by 401 · see citing works

Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance

Bubici, C., Papa, S., Dean, K., & Franzoso, G. (2006) · Oncogene · doi:10.1038/sj.onc.1209936 · Cited by 399 · see citing works

Luteolin suppresses inflammation-associated gene expression by blocking NF-κB and AP-1 activation pathway in mouse alveolar macrophages

Chen, C.-Y., Peng, W.-H., Tsai, K.-D., & Hsu, S.-L. (2007) · Life Sciences · doi:10.1016/j.lfs.2007.09.028 · Cited by 358 · see citing works

Oxidative Stress and Iron Homeostasis: Mechanistic and Health Aspects

Galaris, D., & Pantopoulos, K. (2008) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408360701713104 · Cited by 352 · see citing works

JNK1 and IKKβ: molecular links between obesity and metabolic dysfunction

Solinas, G., & Karin, M. (2010) · The FASEB Journal · doi:10.1096/fj.09-151340 · Cited by 347 · see citing works

TNF-α-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-XL

Kim, J. J., Lee, S. B., Park, J. K., & Yoo, Y. D. (2010) · Cell Death & Differentiation · doi:10.1038/cdd.2010.19 · Cited by 344 · see citing works

The Role of Iron Regulation in Immunometabolism and Immune-Related Disease

Cronin, S. J. F., Woolf, C. J., Weiss, G., & Penninger, J. M. (2019) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2019.00116 · Cited by 299 · see citing works

Iron-withholding strategy in innate immunity

Ong, S. T., Shan Ho, J. Z., Ho, B., & Ding, J. L. (2006) · Immunobiology · doi:10.1016/j.imbio.2006.02.004 · Cited by 269 · see citing works

Heme oxygenase-1: from biology to therapeutic potential

Soares, M. P., & Bach, F. H. (2009) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2008.12.004 · Cited by 257 · see citing works

Oxidative Stress and the Homeodynamics of Iron Metabolism

Bresgen, N., & Eckl, P. (2015) · Biomolecules · doi:10.3390/biom5020808 · Cited by 247 · see citing works

The Iron age of host–microbe interactions

Soares, M. P., & Weiss, G. (2015) · The EMBO Reports · doi:10.15252/embr.201540558 · Cited by 227 · see citing works

TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis

Chen, T. T., Li, L., Chung, D.-H., Allen, C. D. C., Torti, S. V., Torti, F. M., Cyster, J. G., Chen, C.-Y., Brodsky, F. M., Niemi, E. C., et al. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20042433 · Cited by 219 · see citing works

A central role for free heme in the pathogenesis of severe malaria: the missing link?

Ferreira, A., Balla, J., Jeney, V., Balla, G., & Soares, M. P. (2008) · Journal of Molecular Medicine · doi:10.1007/s00109-008-0368-5 · Cited by 205 · see citing works

“Pumping iron”—how macrophages handle iron at the systemic, microenvironmental, and cellular levels

Nairz, M., Theurl, I., Swirski, F. K., & Weiss, G. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1944-8 · Cited by 178 · see citing works

Red alert: labile heme is an alarmin

Soares, M. P., & Bozza, M. T. (2016) · Current Opinion in Immunology · doi:10.1016/j.coi.2015.11.006 · Cited by 148 · see citing works

Coupling Heme and Iron Metabolism <i>via</i> Ferritin H Chain

Gozzelino, R., & Soares, M. P. (2014) · Antioxidants &amp; Redox Signaling · doi:10.1089/ars.2013.5666 · Cited by 151 · see citing works

The Fas Death Signaling Pathway Connecting Reactive Oxygen Species Generation and FLICE Inhibitory Protein Down-Regulation

Wang, L., Azad, N., Kongkaneramit, L., Chen, F., Lu, Y., Jiang, B.-H., & Rojanasakul, Y. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.5.3072 · Cited by 151 · see citing works

Iron in the Tumor Microenvironment-Connecting the Dots

Pfeifhofer-Obermair, C., Tymoszuk, P., Petzer, V., Weiss, G., & Nairz, M. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00549 · Cited by 151 · see citing works

Effect of resistance training on non-alcoholic fatty-liver disease a randomized-clinical trial

Zelber-Sagi, S. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i15.4382 · Cited by 152 · see citing works

Cytotoxicity of TNFα is regulated by integrin‐mediated matrix signaling

Chen, C., Young, J. L., Monzon, R. I., Chen, N., Todorović, V., & Lau, L. F. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601596 · Cited by 143 · see citing works

Iron and innate antimicrobial immunity-depriving the pathogen, defending the host

Nairz, M., Dichtl, S., Schroll, A., Haschka, D., Tymoszuk, P., Theurl, I., & Weiss, G. (2018) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2018.03.007 · Cited by 123 · see citing works

JunD activates transcription of the human ferritin H gene through an antioxidant response element during oxidative stress

Tsuji, Y. (2005) · Oncogene · doi:10.1038/sj.onc.1208901 · Cited by 121 · see citing works

Inhibition of Constitutively Activated Nuclear Factor-κB Induces Reactive Oxygen Species- and Iron-Dependent Cell Death in Cutaneous T-Cell Lymphoma

Kiessling, M. K., Klemke, C. D., Kamiński, M. M., Galani, I. E., Krammer, P. H., & Gülow, K. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-3221 · Cited by 115 · see citing works

Hemin-Mediated Regulation of an Antioxidant-Responsive Element of the Human Ferritin H Gene and Role of Ref-1 during Erythroid Differentiation of K562 Cells

Iwasaki, K., MacKenzie, E. L., Hailemariam, K., Sakamoto, K., & Tsuji, Y. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.7.2845-2856.2006 · Cited by 112 · see citing works

The importance of eukaryotic ferritins in iron handling and cytoprotection

Arosio, P., Carmona, F., Gozzelino, R., Maccarinelli, F., & Poli, M. (2015) · Biochemical Journal · doi:10.1042/bj20150787 · Cited by 104 · see citing works

Tumor necrosis factor-α-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool

Antosiewicz, J., Ziolkowski, W., Kaczor, J. J., & Herman-Antosiewicz, A. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.04.023 · Cited by 102 · see citing works

‘Ride on the ferrous wheel’ – The cycle of iron in macrophages in health and disease

Nairz, M., Schroll, A., Demetz, E., Tancevski, I., Theurl, I., & Weiss, G. (2015) · Immunobiology · doi:10.1016/j.imbio.2014.09.010 · Cited by 89 · see citing works

Conditional deletion of ferritin H in mice induces loss of iron storage and liver damage #

Darshan, D., Vanoaica, L., Richman, L., Beermann, F., & Kühn, L. C. (2009) · Hepatology · doi:10.1002/hep.23058 · Cited by 86 · see citing works

Iron control of erythroid development by a novel aconitase-associated regulatory pathway

Bullock, G. C., Delehanty, L. L., Talbot, A.-L., Gonias, S. L., Tong, W.-H., Rouault, T. A., Dewar, B., Macdonald, J. M., Chruma, J. J., & Goldfarb, A. N. (2010) · Blood · doi:10.1182/blood-2009-10-251496 · Cited by 85 · see citing works

Fas-Mediated Apoptosis Is Regulated by the Extracellular Matrix Protein CCN1 (CYR61) In Vitro and In Vivo

Juric, V., Chen, C.-C., & Lau, L. F. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00064-09 · Cited by 70 · see citing works

Potential Role of Ferritin Heavy Chain in Oxidative Stress and Apoptosis in Human Mesothelial and Mesothelioma Cells: Implications for Asbestos-Induced Oncogenesis

Aung, W., Hasegawa, S., Furukawa, T., & Saga, T. (2007) · Carcinogenesis · doi:10.1093/carcin/bgm090 · Cited by 62 · see citing works

Conditional deletion of ferritin H in mice reduces B and T lymphocyte populations

Vanoaica, L., Richman, L., Jaworski, M., Darshan, D., Luther, S. A., & Kühn, L. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089270 · Cited by 56 · see citing works

Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines

Chen, C., & Lau, L. F. (2010) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-009-0080-4 · Cited by 47 · see citing works

TNFα-induced lysosomal membrane permeability (LMP) is downstream of MOMP and triggered by caspase-mediated p75 cleavage and ROS formation

Huai, J., Vögtle, F.-N., Jöckel, L., Li, Y., Kiefer, T., Ricci, J.-E., & Borner, C. (2013) · Journal of Cell Science · doi:10.1242/jcs.129999 · Cited by 43 · see citing works

Nuclear Factor-κB modulates cellular glutathione and prevents oxidative stress in cancer cells

Meng, Q., Peng, Z., Chen, L., Si, J., Dong, Z., & Xia, Y. (2010) · Cancer Letters · doi:10.1016/j.canlet.2010.08.002 · Cited by 39 · see citing works

XIAP regulates intracellular ROS by enhancing antioxidant gene expression

Resch, U., Schichl, Y. M., Sattler, S., & de Martin, R. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.07.142 · Cited by 41 · see citing works

Mycobacterium avium infection induces H-ferritin expression in mouse primary macrophages by activating Toll-like receptor 2

Silva-Gomes, S., Bouton, C., Silva, T., Santambrogio, P., Rodrigues, P., Appelberg, R., & Gomes, M. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0082874 · Cited by 26 · see citing works

Alternative ferritin mRNA translation via internal initiation

Daba, A., Koromilas, A. E., & Pantopoulos, K. (2012) · RNA · doi:10.1261/rna.029322.111 · Cited by 17 · see citing works

The Extracellular Matrix Protein CCN1 Dictates TNFα and FasL Cytotoxicity In Vivo

Chen, C.-C., Juric, V., & Lau, L. F. (2011) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4419-6612-4_63 · Cited by 8 · see citing works

Metabolic adaptation to tissue iron overload confers tolerance to malaria

Gozzelino, R., Andrade, B. B., Larsen, R., Luz, N. F., Vanoaica, L., Seixas, E., Coutinho, A., Cardoso, S., Rebelo, S., Poli, M., et al. (2012) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2012.10.011 · Cited by 3 · see citing works

NF-.KAPPA.B as a therapeutic target of rheumatoid arthritis

Okamoto, T., & Tsuchiya, A. (2007) · Japanese Journal of Clinical Immunology · doi:10.2177/jsci.30.383 · Cited by 2 · see citing works

Glossogyne tenuifolia acts to inhibit inflammatory mediator production in a macrophage cell line by downregulating LPS-induced NF-κB

Wu, M., Wang, L., Ding, H., et al. (2004) · Journal of Biomedical Science · doi:10.1007/bf02256562 · Cited by 63 · see citing works

BCL2-associated athanogene 3 (BAG3); NF-kappa B (NF-kB)

(2010) · Science-Business eXchange · doi:10.1038/scibx.2010.488

Regulation of the Nuclear Factor (NF)-.KAPPA.B Pathway by ISGylation

Minakawa, M., Sone, T., Takeuchi, T., et al. (2008) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.31.2223 · Cited by 30 · see citing works

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