Polonsky, Kenneth S.

International trial of the Edmonton protocol for islet transplantation

Shapiro, A. M. J., Ricordi, C., Hering, B. J., Auchincloss, H., Lindblad, R., Robertson, R. P., Secchi, A., Brendel, M. D., Berney, T., Brennan, D. C., et al. (2006) · New England Journal of Medicine

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 1,942

Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young

Fajans, S. S., Bell, G. I., & Polonsky, K. S. (2001) · New England Journal of Medicine

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 1,123

Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects.

Polonsky, K. S., Given, B. D., & Van Cauter, E. (1988) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 763

Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus.

Polonsky, K. S., Given, B. D., Hirsch, L. J., Tillil, H., Shapiro, E. T., Beebe, C., Frank, B. H., Galloway, J. A., & Van Cauter, E. (1988) · New England Journal of Medicine

Pancreatic function and diabetesDiabetes Management and Research

Cited by 567

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

Pick, A., Clark, J., Kubstrup, C., Levisetti, M., Pugh, W., Bonner-Weir, S., & Polonsky, K. S. (1998) · Diabetes

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 551

C-Peptide Is the Appropriate Outcome Measure for Type 1 Diabetes Clinical Trials to Preserve β-Cell Function

Palmer, J. P., Fleming, G. A., Greenbaum, C. J., Herold, K. C., Jansa, L. D., Kolb, H., Lachin, J. M., Polonsky, K. S., Pozzilli, P., Skyler, J. S., et al. (2004) · Diabetes

Diabetes and associated disordersDiabetes Management and Research

Cited by 491

Diabetes mellitus and genetically programmed defects in β-cell function

Bell, G. I., & Polonsky, K. S. (2001) · Nature

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 475

Troglitazone Improves Defects in Insulin Action, Insulin Secretion, Ovarian Steroidogenesis, and Fibrinolysis in Women with Polycystic Ovary Syndrome1

Ehrmann, D. A., Schneider, D. J., Sobel, B. E., Cavaghan, M. K., Imperial, J., Rosenfield, R. L., & Polonsky, K. S. (1997) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 461

β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment

Halban, P. A., Polonsky, K. S., Bowden, D. W., Hawkins, M. A., Ling, C., Mather, K. J., Powers, A. C., Rhodes, C. J., Sussel, L., & Weir, G. C. (2014) · Diabetes Care

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 460

Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep

Van Cauter, E., Blackman, J. D., Roland, D., Spire, J. P., Refetoff, S., & Polonsky, K. S. (1991) · Journal of Clinical Investigation

Circadian rhythm and melatoninPancreatic function and diabetes

Cited by 448

Quantitative study of insulin secretion and clearance in normal and obese subjects

Polonsky, K. S., Given, B. D., Hirsch, L., Shapiro, E. T., Tillil, H., Beebe, C., Galloway, J. A., Frank, B. H., Karrison, T., & Van Cauter, E. (1988) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 444

Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus.

Ehrmann, D. A., Sturis, J., Byrne, M. M., Karrison, T., Rosenfield, R. L., & Polonsky, K. S. (1995) · Journal of Clinical Investigation

Ovarian function and disordersPancreatic function and diabetes

Cited by 426

Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients.

Polonsky, K. S., Licinio-Paixao, J., Given, B. D., Pugh, W., Rue, P., Galloway, J., Karrison, T., & Frank, B. (1986) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes Management and Research

Cited by 359

Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.

Pontoglio, M., Sreenan, S., Roe, M., Pugh, W., Ostrega, D., Doyen, A., Pick, A. J., Baldwin, A., Velho, G., Froguel, P., et al. (1998) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 321

Oral Glucose Tolerance Test Minimal Model Indexes of β-Cell Function and Insulin Sensitivity

Breda, E., Cavaghan, M. K., Toffolo, G., Polonsky, K. S., & Cobelli, C. (2001) · Diabetes

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 320

Insulin Signaling in α Cells Modulates Glucagon Secretion In Vivo

Kawamori, D., Kurpad, A. J., Hu, J., Liew, C. W., Shih, J. L., Ford, E. L., Herrera, P. L., Polonsky, K. S., McGuinness, O. P., & Kulkarni, R. N. (2009) · Cell Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 316

Computer model for mechanisms underlying ultradian oscillations of insulin and glucose

Sturis, J., Polonsky, K. S., Mosekilde, E., & Van Cauter, E. (1991) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesDiabetes Management and Research

Cited by 251

Circadian modulation of glucose and insulin responses to meals: relationship to cortisol rhythm

Van Cauter, E., Shapiro, E. T., Tillil, H., & Polonsky, K. S. (1992) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesCircadian rhythm and melatonin

Cited by 240

Impaired Processing of Prohormones Associated with Abnormalities of Glucose Homeostasis and Adrenal Function

O'Rahilly, S., Gray, H., Humphreys, P. J., Krook, A., Polonsky, K. S., White, A., Gibson, S., Taylor, K., & Carr, C. (1995) · New England Journal of Medicine

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 237

Metabolic Effects of Short-Term Elevations of Plasma Cortisol Are More Pronounced in the Evening Than in the Morning1

Plat, L., Leproult, R., L’Hermite-Baleriaux, M., Fery, F., Mockel, J., Polonsky, K. S., & Van Cauter, E. (1999) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersPancreatic function and diabetes

Cited by 225

Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance.

Cavaghan, M. K., Ehrmann, D. A., Byrne, M. M., & Polonsky, K. S. (1997) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 216

Plasma insulin, C-peptide, and proinsulin concentrations in obese and nonobese individuals with varying degrees of glucose tolerance.

Reaven, G. M., Chen, Y. D., Hollenbeck, C. B., Sheu, W. H., Ostrega, D., & Polonsky, K. S. (1993) · The Journal of Clinical Endocrinology & Metabolism

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 214

Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO mice

Otani, K., Kulkarni, R. N., Baldwin, A. C., Krutzfeldt, J., Ueki, K., Stoffel, M., Kahn, C. R., & Polonsky, K. S. (2004) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 185

Targeted Ablation of Glucose-dependent Insulinotropic Polypeptide-producing Cells in Transgenic Mice Reduces Obesity and Insulin Resistance Induced by a High Fat Diet

Althage, M. C., Ford, E. L., Wang, S., Tso, P., Polonsky, K. S., & Wice, B. M. (2008) · Journal of Biological Chemistry

Regulation of Appetite and ObesityPancreatic function and diabetes

Cited by 180