Bird, Thomas D.

TREM2 haplodeficiency in mice and humans impairs the microglia barrier function leading to decreased amyloid compaction and severe axonal dystrophy

Yuan, P., Condello, C., Keene, C. D., Wang, Y., Bird, T. D., Paul, S. M., Luo, W., Colonna, M., Baddeley, D., & Grutzendler, J. (2016) · Neuron

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

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Transethnic genome‐wide scan identifies novel Alzheimer's disease loci

Jun, G. R., Chung, J., Mez, J., Barber, R., Beecham, G. W., Bennett, D. A., Buxbaum, J. D., Byrd, G. S., Carrasquillo, M. M., Crane, P. K., et al. (2017) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 197

The Spectrum of Mutations in Progranulin: A Collaborative Study Screening 545 Cases of Neurodegeneration

Yu, C.-E., Bird, T. D., Bekris, L. M., Montine, T. J., Leverenz, J. B., Steinbart, E., Galloway, N. M., Feldman, H., Woltjer, R., Miller, C. A., et al. (2010) · Archives of Neurology

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 190

Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease: A Genome-Wide Association Study

Naj, A. C., Jun, G., Reitz, C., Kunkle, B. W., Perry, W., Park, Y. S., Beecham, G. W., Rajbhandary, R. A., Hamilton-Nelson, K. L., Wang, L.-S., et al. (2014) · JAMA Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 185

Amyloid β protein (Aβ) deposition in chromosome 14–linked Alzheimer's disease: Predominance of Aβ42(43)

Mann, D. M. A., Iwatsubo, T., Cairns, N. J., Lantos, P. L., Nochlin, D., Sumi, S. M., Bird, T. D., Poorkaj, P., Hardy, J., Hutton, M., et al. (1996) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 184

Frequency of Tau Gene Mutations in Familial and Sporadic Cases of Non-Alzheimer Dementia

Poorkaj, P., Grossman, M., Steinbart, E., Payami, H., Sadovnick, A., Nochlin, D., Tabira, T., Trojanowski, J. Q., Borson, S., Galasko, D., et al. (2001) · Archives of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 171

Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS)

Korvatska, O., Strand, N. S., Berndt, J. D., Strovas, T., Chen, D.-H., Leverenz, J. B., Kiianitsa, K., Mata, I. F., Karakoc, E., Greenup, J. L., et al. (2013) · Human Molecular Genetics

Parkinson's Disease Mechanisms and TreatmentsRNA Research and Splicing

Cited by 140

Lewy Body Pathology in Familial Alzheimer Disease: Evidence for Disease- and Mutation-Specific Pathologic Phenotype

Leverenz, J. B., Fishel, M. A., Peskind, E. R., Montine, T. J., Nochlin, D., Steinbart, E., Raskind, M. A., Schellenberg, G. D., Bird, T. D., & Tsuang, D. (2006) · Archives of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 139

R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study

Korvatska, O., Leverenz, J. B., Jayadev, S., McMillan, P., Kurtz, I., Guo, X., Rumbaugh, M., Matsushita, M., Girirajan, S., Dorschner, M. O., et al. (2015) · JAMA Neurology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 137

A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology

Leverenz, J. B., Yu, C. E., Montine, T. J., Steinbart, E., Bekris, L. M., Zabetian, C., Kwong, L. K., Lee, V. M.-Y., Schellenberg, G. D., & Bird, T. D. (2007) · Brain

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 129

Gain‐of‐function ADCY5 mutations in familial dyskinesia with facial myokymia

Chen, Y., Friedman, J. R., Chen, D., Chan, G. C. ‐., Bloss, C. S., Hisama, F. M., Topol, S. E., Carson, A. R., Pham, P. H., Bonkowski, E. S., et al. (2014) · Annals of Neurology

Neurological and metabolic disordersDeep Brain Stimulation and Movement Disorders

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Genetic and Clinical Features of Progranulin-Associated Frontotemporal Lobar Degeneration

Chen-Plotkin, A. S., Martinez-Lage, M., Sleiman, P. M. A., Hu, W., Greene, R., Wood, E. M., Bing, S., Grossman, M., Schellenberg, G. D., Hatanpaa, K. J., et al. (2011) · Archives of Neurology

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 120

Familial presenile dementia with psychosis associated with cortical neurofibrillary tangles and degeneration of the amygdala

Sumi, S. M., Bird, T. D., Nochlin, D., & Raskind, M. A. (1992) · Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 118

Clinical and Neuropathological Features of the Arctic APP Gene Mutation Causing Early-Onset Alzheimer Disease

Basun, H., Bogdanovic, N., Ingelsson, M., Almkvist, O., Näslund, J., Axelman, K., Bird, T. D., Nochlin, D., Schellenberg, G. D., Wahlund, L.-O., et al. (2008) · Archives of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 115

Hereditary diffuse leukoencephalopathy with spheroids: clinical, pathologic and genetic studies of a new kindred

Baba, Y., Ghetti, B., Baker, M. C., Uitti, R. J., Hutton, M. L., Yamaguchi, K., Bird, T., Lin, W., DeLucia, M. W., Dickson, D. W., et al. (2006) · Acta Neuropathologica

Hereditary Neurological DisordersAlzheimer's disease research and treatments

Cited by 106

ABCA7 frameshift deletion associated with Alzheimer disease in African Americans

Cukier, H. N., Kunkle, B. W., Vardarajan, B. N., Rolati, S., Hamilton-Nelson, K. L., Kohli, M. A., Whitehead, P. L., Dombroski, B. A., Van Booven, D., Lang, R., et al. (2016) · Neurology Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 100

Endocytic disturbances distinguish among subtypes of alzheimer's disease and related disorders

Cataldo, A., Rebeck, G. W., Ghetti, B., Hulette, C., Lippa, C., Van Broeckhoven, C., Van Duijn, C., Cras, P., Bogdanovic, N., Bird, T., et al. (2001) · Annals of Neurology

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 90

APOE and other loci affect age‐at‐onset in Alzheimer's disease families with PS2 mutation

Wijsman, E. M., Daw, E. W., Yu, X., Steinbart, E. J., Nochlin, D., Bird, T. D., & Schellenberg, G. D. (2005) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 79

Early-Onset Alzheimer Disease in Families With Late-Onset Alzheimer Disease: A Potential Important Subtype of Familial Alzheimer Disease

Brickell, K. L., Steinbart, E. J., Rumbaugh, M., Payami, H., Schellenberg, G. D., Van Deerlin, V., Yuan, W., & Bird, T. D. (2006) · Archives of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 77

Amyloid angiopathy in a volga german family with Alzheimer's disease and a presenilin‐2 mutation (N141I)

Nochlin, D., Bird, T. D., Nemens, E. J., Ball, M. J., & Sumi, S. M. (1998) · Annals of Neurology

Alzheimer's disease research and treatmentsIntracerebral and Subarachnoid Hemorrhage Research

Cited by 75

Recovery from barbiturate overdose coma with a prolonged isoelectric electroencephalogram

Bird, T. D., & Plum, F. (1968) · Neurology

Poisoning and overdose treatmentsTraumatic Brain Injury Research

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Age-Specific Incidence Rates for Dementia and Alzheimer Disease in NIA-LOAD/NCRAD and EFIGA Families: National Institute on Aging Genetics Initiative for Late-Onset Alzheimer Disease/National Cell Repository for Alzheimer Disease (NIA-LOAD/NCRAD) and Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA)

Vardarajan, B. N., Faber, K. M., Bird, T. D., Bennett, D. A., Rosenberg, R., Boeve, B. F., Graff-Radford, N. R., Goate, A. M., Farlow, M., Sweet, R. A., et al. (2014) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia

Shade, L. M. P., Katsumata, Y., Abner, E. L., Aung, K. Z., Claas, S. A., Qiao, Q., Heberle, B. A., Brandon, J. A., Page, M. L., Hohman, T. J., et al. (2024) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 72

The Clinical phenotype of two missense mutations in the presenilin I gene in Japanese patients

Ikeda, M., Sharma, V., Mark Sumi, S., Rogaeva, E. A., Poorkaj, P., Sherrington, R., Nee, L., Tsuda, T., Oda, N., Watanabe, M., et al. (1996) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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