Göke, Burkhard

Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.

Göke, R., Fehmann, H. C., Linn, T., Schmidt, H., Krause, M., Eng, J., & Göke, B. (1993) · Journal of Biological Chemistry

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 837

Glucagon‐like peptide‐1 cells in the gastrointestinal tract and pancreas of rat, pig and man

EISSELE, R., GÖKE, R., WILLEMER, S., HARTHUS, H. ‐., VERMEER, H., ARNOLD, R., & GÖKE, B. (1992) · European Journal of Clinical Investigation

Diabetes Treatment and ManagementNeuropeptides and Animal Physiology

Cited by 654

Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients

Herrmann, C., Göke, R., Richter, G., Fehmann, H.-C., Arnold, R., & Göke, B. (2009) · Digestion

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 597

Impact of fasting and postprandial glycemia on overall glycemic control in type 2 diabetes

Woerle, H. J., Neumann, C., Zschau, S., Tenner, S., Irsigler, A., Schirra, J., Gerich, J. E., & Göke, B. (2007) · Diabetes Research and Clinical Practice

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 316

Exendin(9-39)amide is an antagonist of glucagon-like peptide-1(7-36)amide in humans

Schirra, J., Sturm, K., Leicht, P., Arnold, R., Göke, B., & Katschinski, M. (1998) · Journal of Clinical Investigation

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 265

Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7–36) amide and comparison of the substrate specificity of the enzyme for other glucagon-like peptides

Hupe-Sodmann, K., McGregor, G. P., Bridenbaugh, R., Göke, R., Göke, B., Thole, H., Zimmermann, B., & Voigt, K. (1995) · Regulatory Peptides

Diabetes Treatment and ManagementPeptidase Inhibition and Analysis

Cited by 224

Effects of glucagon-like peptide-1(7-36)amide on antro-pyloro-duodenal motility in the interdigestive state and with duodenal lipid perfusion in humans

Schirra, J., Houck, P., Wank, U., Arnold, R., Göke, B., & Katschinski, M. (2000) · Gut

Gastrointestinal motility and disordersDiabetes Treatment and Management

Cited by 145

Effects of glucagon-like peptide-1(7–36)amide on motility and sensation of the proximal stomach in humans

Schirra, J., Wank, U., Arnold, R., Göke, B., & Katschinski, M. (2002) · Gut

Gastrointestinal motility and disordersRegulation of Appetite and Obesity

Cited by 130

Molecular cloning, functional expression, and signal transduction of the GIP‐receptor cloned from a human insulinoma

Volz, A., Göke, R., Lankat-Buttgereit, B., Fehmann, H.-C., Bode, H. P., & Göke, B. (1995) · FEBS Letters

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 96

Formation of antinuclear and double-strand DNA antibodies and frequency of lupus-like syndrome in anti-TNF-α antibody-treated patients with inflammatory bowel disease

Beigel, F., Schnitzler, F., Paul Laubender, R., Pfennig, S., Weidinger, M., Göke, B., Seiderer, J., Ochsenkühn, T., & Brand, S. (2011) · Inflammatory Bowel Diseases

Systemic Lupus Erythematosus ResearchInflammatory Bowel Disease

Cited by 84

The Role of Endogenous Incretin Secretion as Amplifier of Glucose-Stimulated Insulin Secretion in Healthy Subjects and Patients With Type 2 Diabetes

Woerle, H. J., Carneiro, L., Derani, A., Göke, B., & Schirra, J. (2012) · Diabetes

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 73

Islet cell function: α and β cells - partners towards normoglycaemia: α and β cells and normoglycaemia

Göke, B. (2008) · International Journal of Clinical Practice

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 58

A nutrient-regulated cytosolic calcium oscillator in endocrine pancreatic glucagon-secreting cells

Bode, H.-P., Weber, S., Fehmann, H.-C., & Göke, B. (1999) · Pfl�gers Archiv European Journal of Physiology

Pancreatic function and diabetesCalcium signaling and nucleotide metabolism

Cited by 28

Acute hyperglycemia alters the ability of the normal β-cell to sense and respond to glucose

Meyer, J., Sturis, J., Katschinski, M., Arnold, R., Göke, B., & Byrne, M. M. (2002) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 25