Most cited biochemistry, genetics and molecular biology papers
- Verified
Structure of Hsp90–Hsp70–Hop–GR reveals the Hsp90 client-loading mechanism
Wang, R. Y.-R., Noddings, C. M., Kirschke, E., Myasnikov, A. G., Johnson, J. L., & Agard, D. A. (2022) · Nature
Heat shock proteins researchProtein Structure and Dynamics
Cited by 220
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Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site
Mazhab-Jafari, M. T., Marshall, C. B., Smith, M. J., Gasmi-Seabrook, G. M. C., Stathopulos, P. B., Inagaki, F., Kay, L. E., Neel, B. G., & Ikura, M. (2015) · Proceedings of the National Academy of Sciences
Protein Kinase Regulation and GTPase SignalingLipid Membrane Structure and Behavior
Cited by 220
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Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles
Masiero, E., & Sandri, M. (2010) · Autophagy
Muscle Physiology and DisordersAutophagy in Disease and Therapy
Cited by 220
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Nutritional risk predictors of β cell autoimmunity and type 1 diabetes at a young age
Virtanen, S. M., & Knip, M. (2003) · The American Journal of Clinical Nutrition
Diabetes and associated disordersNutritional Studies and Diet
Cited by 220
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Excess Membrane Synthesis Drives a Primitive Mode of Cell Proliferation
Mercier, R., Kawai, Y., & Errington, J. (2013) · Cell
Bacterial Genetics and BiotechnologyOrigins and Evolution of Life
Cited by 220
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Energy Conservation Associated with Ethanol Formation from H 2 and CO 2 in Clostridium autoethanogenum Involving Electron Bifurcation
Mock, J., Zheng, Y., Mueller, A. P., Ly, S., Tran, L., Segovia, S., Nagaraju, S., Köpke, M., Dürre, P., & Thauer, R. K. (2015) · Journal of Bacteriology
Microbial Metabolic Engineering and BioproductionAnaerobic Digestion and Biogas Production
Cited by 220
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Molecular Mechanisms of Presynaptic Membrane Retrieval and Synaptic Vesicle Reformation
Kononenko, N. L., & Haucke, V. (2015) · Neuron
Cellular transport and secretionNeuroscience and Neuropharmacology Research
Cited by 220
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Strict vegetarian diet improves the risk factors associated with metabolic diseases by modulating gut microbiota and reducing intestinal inflammation
Kim, M., Hwang, S., Park, E., & Bae, J. (2013) · Environmental Microbiology Reports
Gut microbiota and healthNutritional Studies and Diet
Cited by 220
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Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer
Cao, O., Dobrzynski, E., Wang, L., Nayak, S., Mingle, B., Terhorst, C., & Herzog, R. W. (2007) · Blood
Virus-based gene therapy researchT-cell and B-cell Immunology
Cited by 220
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Interaction between Wnt/β-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of β-catenin and RAS by targeting the Wnt/β-catenin pathway
Jeong, W.-J., Ro, E. J., & Choi, K.-Y. (2018) · npj Precision Oncology
Wnt/β-catenin signaling in development and cancerColorectal Cancer Treatments and Studies
Cited by 220
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3-[(1 S ,2 S ,3 R )-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma
Xu, R., Wang, K., Rizzi, J. P., Huang, H., Grina, J. A., Schlachter, S. T., Wang, B., Wehn, P. M., Yang, H., Dixon, D. D., et al. (2019) · Journal of Medicinal Chemistry
Cancer, Hypoxia, and MetabolismHeterocyclic Compound Synthesis and Bioactivity
Cited by 220
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Endurance training and detraining in mitochondrial myopathies due to single large-scale mtDNA deletions
Taivassalo, T., Gardner, J. L., Taylor, R. W., Schaefer, A. M., Newman, J., Barron, M. J., Haller, R. G., & Turnbull, D. M. (2006) · Brain
Mitochondrial Function and PathologyCardiovascular and exercise physiology
Cited by 220
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AMP-activated Protein Kinase Regulates HNF4α Transcriptional Activity by Inhibiting Dimer Formation and Decreasing Protein Stability
Hong, Y. H., Varanasi, U. S., Yang, W., & Leff, T. (2003) · Journal of Biological Chemistry
Metabolism, Diabetes, and CancerPeroxisome Proliferator-Activated Receptors
Cited by 220
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Hormonal control of pyruvate kinase activity and of gluconeogenesis in isolated hepatocytes.
Feliú, J. E., Hue, L., & Hers, H. G. (1976) · Proceedings of the National Academy of Sciences
Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus
Cited by 220
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Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling
Peng, M., Yin, N., & Li, M. O. (2014) · Cell
PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy
Cited by 220
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Engineering herbicide resistance via prime editing in rice
Butt, H., Rao, G. S., Sedeek, K., Aman, R., Kamel, R., & Mahfouz, M. (2020) · Plant Biotechnology Journal
CRISPR and Genetic EngineeringGenetically Modified Organisms Research
Cited by 220
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NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice
Marín‐Aguilar, F., Lechuga‐Vieco, A. V., Alcocer‐Gómez, E., Castejón‐Vega, B., Lucas, J., Garrido, C., Peralta‐Garcia, A., Pérez‐Pulido, A. J., Varela‐López, A., Quiles, J. L., et al. (2020) · Aging Cell
Inflammasome and immune disordersGenetics, Aging, and Longevity in Model Organisms
Cited by 220
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DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity
Sengupta Ghosh, A., Wang, B., Pozniak, C. D., Chen, M., Watts, R. J., & Lewcock, J. W. (2011) · Journal of Cell Biology
Cell death mechanisms and regulationNerve injury and regeneration
Cited by 220
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cGMP-dependent protein kinase phosphorylates and inactivates RhoA
Sawada, N., Itoh, H., Yamashita, J., Doi, K., Inoue, M., Masatsugu, K., Fukunaga, Y., Sakaguchi, S., Sone, M., Yamahara, K.-I., et al. (2001) · Biochemical and Biophysical Research Communications
Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions
Cited by 220
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FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders
Lehtonen, J. M., Forsström, S., Bottani, E., Viscomi, C., Baris, O. R., Isoniemi, H., Höckerstedt, K., Österlund, P., Hurme, M., Jylhävä, J., et al. (2016) · Neurology
Mitochondrial Function and PathologyFibroblast Growth Factor Research
Cited by 220
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CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein
Tang, L., Zeng, Y., Du, H., Gong, M., Peng, J., Zhang, B., Lei, M., Zhao, F., Wang, W., Li, X., et al. (2017) · Molecular Genetics and Genomics
CRISPR and Genetic EngineeringAnimal Genetics and Reproduction
Cited by 220
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After Cellular Internalization, Quercetin Causes Nrf2 Nuclear Translocation, Increases Glutathione Levels, and Prevents Neuronal Death against an Oxidative Insult
Arredondo, F., Echeverry, C., Abin-Carriquiry, J. A., Blasina, F., Antúnez, K., Jones, D. P., Go, Y.-M., Liang, Y.-L., & Dajas, F. (2010) · Free Radical Biology and Medicine
Genomics, phytochemicals, and oxidative stressPhytochemicals and Antioxidant Activities
Cited by 220
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Identification of a large set of rare complete human knockouts
Sulem, P., Helgason, H., Oddson, A., Stefansson, H., Gudjonsson, S. A., Zink, F., Hjartarson, E., Sigurdsson, G. T., Jonasdottir, A., Jonasdottir, A., et al. (2015) · Nature Genetics
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 220
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Neurotrophic Effects of Vascular Endothelial Growth Factor on Organotypic Cortical Explants and Primary Cortical Neurons
Rosenstein, J. M., Mani, N., Khaibullina, A., & Krum, J. M. (2003) · The Journal of Neuroscience
Angiogenesis and VEGF in CancerNerve injury and regeneration
Cited by 220
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