Most cited biochemistry, genetics and molecular biology papers
- Verified
mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation
Damsky, W., Micevic, G., Meeth, K., Muthusamy, V., Curley, D. P., Santhanakrishnan, M., Erdelyi, I., Platt, J. T., Huang, L., Theodosakis, N., et al. (2015) · Cancer Cell
Melanoma and MAPK PathwaysPI3K/AKT/mTOR signaling in cancer
Cited by 142
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Histone acetylation regulates chromatin accessibility: Role of H4K16 in inter-nucleosome interaction
Zhang, R., Erler, J., & Langowski, J. (2017) · Biophysical Journal
Genomics and Chromatin DynamicsProtein Structure and Dynamics
Cited by 142
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Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy
Morvan, F., Rondeau, J.-M., Zou, C., Minetti, G., Scheufler, C., Scharenberg, M., Jacobi, C., Brebbia, P., Ritter, V., Toussaint, G., et al. (2017) · Proceedings of the National Academy of Sciences
Muscle Physiology and DisordersTGF-β signaling in diseases
Cited by 142
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Physiological and Pharmacological Control of BAK, BAX, and Beyond
Luna-Vargas, M. P. A., & Chipuk, J. E. (2016) · Trends in Cell Biology
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 142
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CZ CELL×GENE Discover: A single-cell data platform for scalable exploration, analysis and modeling of aggregated data
Program, C. S.-C. B., Abdulla, S., Aevermann, B., Assis, P., Badajoz, S., Bell, S. M., Bezzi, E., Cakir, B., Chaffer, J., Chambers, S., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)
Single-cell and spatial transcriptomicsScientific Computing and Data Management
Cited by 142
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Dental Pulp Stem Cell-Derived Secretome and Its Regenerative Potential
Bar, J. K., Lis-Nawara, A., & Grelewski, P. G. (2021) · International Journal of Molecular Sciences
Mesenchymal stem cell researchPeriodontal Regeneration and Treatments
Cited by 142
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Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha‐1‐anti‐trypsin deficiency
Pastore, N., Blomenkamp, K., Annunziata, F., Piccolo, P., Mithbaokar, P., Maria Sepe, R., Vetrini, F., Palmer, D., Ng, P., Polishchuk, E., et al. (2013) · EMBO Molecular Medicine
Autophagy in Disease and TherapyVirus-based gene therapy research
Cited by 142
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Protein Kinase C Alters the Responsiveness of Adenylyl Cyclases to G Protein α and βγ Subunits
Zimmermann, G., & Taussig, R. (1996) · Journal of Biological Chemistry
Protein Kinase Regulation and GTPase SignalingReceptor Mechanisms and Signaling
Cited by 142
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Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease
Cain, A., Taga, M., McCabe, C., Green, G. S., Hekselman, I., White, C. C., Lee, D. I., Gaur, P., Rozenblatt-Rosen, O., Zhang, F., et al. (2023) · Nature Neuroscience
Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments
Cited by 142
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Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals
Fackelmann, G., Manghi, P., Carlino, N., Heidrich, V., Piccinno, G., Ricci, L., Piperni, E., Arrè, A., Bakker, E., Creedon, A. C., et al. (2025) · Nature Microbiology
Gut microbiota and healthNutritional Studies and Diet
Cited by 142
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Community-Wide Response of the Gut Microbiota to Enteropathogenic Citrobacter rodentium Infection Revealed by Deep Sequencing
Hoffmann, C., Hill, D. A., Minkah, N., Kirn, T., Troy, A., Artis, D., & Bushman, F. (2009) · Infection and Immunity
Gut microbiota and healthEscherichia coli research studies
Cited by 142
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Pain associated with photodynamic therapy using 5-aminolevulinic acid or 5-aminolevulinic acid methylester on tape-stripped normal skin
Wiegell, S. R. (2003) · Archives of Dermatology
Photodynamic Therapy Research StudiesNonmelanoma Skin Cancer Studies
Cited by 142
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ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway
Moskal, N., Riccio, V., Bashkurov, M., Taddese, R., Datti, A., Lewis, P. N., & Angus McQuibban, G. (2020) · Nature Communications
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments
Cited by 142
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The oxidative DNA lesions 8,5′-cyclopurines accumulate with aging in a tissue-specific manner
Wang, J., Clauson, C. L., Robbins, P. D., Niedernhofer, L. J., & Wang, Y. (2012) · Aging Cell
Genetics, Aging, and Longevity in Model OrganismsDNA Repair Mechanisms
Cited by 142
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The Heat Shock Protein 90 Inhibitor, 17-Allylamino-17-demethoxygeldanamycin, Enhances Osteoclast Formation and Potentiates Bone Metastasis of a Human Breast Cancer Cell Line
Price, J. T., Quinn, J. M. W., Sims, N. A., Vieusseux, J., Waldeck, K., Docherty, S. E., Myers, D., Nakamura, A., Waltham, M. C., Gillespie, M. T., et al. (2005) · Cancer Research
Heat shock proteins researchBone Metabolism and Diseases
Cited by 142
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A Reexamination of the Nucleotide Incorporation Fidelity of DNA Polymerases
Showalter, A. K., & Tsai, M.-D. (2002) · Biochemistry
DNA and Nucleic Acid ChemistryProtein Structure and Dynamics
Cited by 142
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The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5’ cap modulates protein expression in living cells
Sikorski, P. J., Warminski, M., Kubacka, D., Ratajczak, T., Nowis, D., Kowalska, J., & Jemielity, J. (2020) · Nucleic Acids Research
RNA modifications and cancerRNA and protein synthesis mechanisms
Cited by 142
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Adrenoleukodystrophy: New Approaches to a Neurodegenerative Disease
Moser, H. W., Raymond, G. V., & Dubey, P. (2005) · JAMA
Metabolism and Genetic DisordersLysosomal Storage Disorders Research
Cited by 142
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Impaired Activation of Glycogen Synthase in People at Increased Risk for Developing NIDDM
Schalin-Jäntti, C., Härkönen, M., & Groop, L. C. (1992) · Diabetes
Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 142
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Ultrafine particulate matter and high-level benzene urban air pollution in relation to oxidative DNA damage
Avogbe, P. H. (2004) · Carcinogenesis
Carcinogens and Genotoxicity AssessmentAir Quality and Health Impacts
Cited by 142
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Role of T cells in ovariectomy induced bone loss—revisited
Pacifici, R. (2012) · Journal of Bone and Mineral Research
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 142
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Defective Initiation of Glycosaminoglycan Synthesis due to B3GALT6 Mutations Causes a Pleiotropic Ehlers-Danlos-Syndrome-like Connective Tissue Disorder
Malfait, F., Kariminejad, A., Van Damme, T., Gauche, C., Syx, D., Merhi-Soussi, F., Gulberti, S., Symoens, S., Vanhauwaert, S., Willaert, A., et al. (2013) · The American Journal of Human Genetics
Proteoglycans and glycosaminoglycans researchConnective tissue disorders research
Cited by 142
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Notch signaling in developmental and tumor angiogenesis
Kofler, N. M., Shawber, C. J., Kangsamaksin, T., Reed, H. O., Galatioto, J., & Kitajewski, J. (2011) · Genes & Cancer
Angiogenesis and VEGF in CancerDevelopmental Biology and Gene Regulation
Cited by 142
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Deletion of the α-Arrestin Protein Txnip in Mice Promotes Adiposity and Adipogenesis While Preserving Insulin Sensitivity
Chutkow, W. A., Birkenfeld, A. L., Brown, J. D., Lee, H.-Y., Frederick, D. W., Yoshioka, J., Patwari, P., Kursawe, R., Cushman, S. W., Plutzky, J., et al. (2010) · Diabetes
Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases
Cited by 142
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