Most cited biochemistry, genetics and molecular biology papers
- Verified
Gut microbiota promotes obesity-associated liver cancer through pge2-mediated suppression of antitumor immunity.
Loo, T. M., Kamachi, F., Watanabe, Y., Yoshimoto, S., Kanda, H., Arai, Y., Nakajima-Takagi, Y., Iwama, A., Koga, T., Sugimoto, Y., et al. (2017) · Cancer Discovery
Gut microbiota and healthHepatocellular Carcinoma Treatment and Prognosis
Cited by 478
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Genetics meets proteomics: perspectives for large population-based studies
Suhre, K., McCarthy, M. I., & Schwenk, J. M. (2021) · Nature Reviews Genetics
Genetic Associations and EpidemiologyBioinformatics and Genomic Networks
Cited by 478
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Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
Trevino, A. E., Müller, F., Andersen, J., Sundaram, L., Kathiria, A., Shcherbina, A., Farh, K., Chang, H. Y., Pașca, A. M., Kundaje, A., et al. (2021) · Cell
Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics
Cited by 478
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Mechanism and Applications of CRISPR/Cas-9-Mediated Genome Editing
Mengstie, M. A., & Wondimu, B. Z. (2021) · Biologics: Targets and Therapy
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 478
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The genetics of Mexico recapitulates Native American substructure and affects biomedical traits
Moreno-Estrada, A., Gignoux, C. R., Fernández-López, J. C., Zakharia, F., Sikora, M., Contreras, A. V., Acuña-Alonzo, V., Sandoval, K., Eng, C., Romero-Hidalgo, S., et al. (2014) · Science
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 478
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Multifaceted Role of the Urokinase-Type Plasminogen Activator (uPA) and Its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications
Mahmood, N., Mihalcioiu, C., & Rabbani, S. A. (2018) · Frontiers in Oncology
Protease and Inhibitor MechanismsBlood Coagulation and Thrombosis Mechanisms
Cited by 478
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The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
Vincow, E. S., Merrihew, G., Thomas, R. E., Shulman, N. J., Beyer, R. P., MacCoss, M. J., & Pallanck, L. J. (2013) · Proceedings of the National Academy of Sciences
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments
Cited by 478
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Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo
Nakai, H., Yant, S. R., Storm, T. A., Fuess, S., Meuse, L., & Kay, M. A. (2001) · Journal of Virology
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 478
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Biosynthesis of Plant Isoprenoids: Perspectives for Microbial Engineering
Kirby, J., & Keasling, J. D. (2009) · Annual Review of Plant Biology
Plant biochemistry and biosynthesisMicrobial Metabolic Engineering and Bioproduction
Cited by 478
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Relation of hypoxia inducible factor 1α and 2α in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival
Giatromanolaki, A., Koukourakis, M. I., Sivridis, E., Turley, H., Talks, K., Pezzella, F., Gatter, K. C., & Harris, A. L. (2001) · British Journal of Cancer
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 478
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Rapid Conduction and the Evolution of Giant Axons and Myelinated Fibers
Hartline, D. K., & Colman, D. R. (2007) · Current Biology
Ion channel regulation and functionNeurogenesis and neuroplasticity mechanisms
Cited by 478
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Short tandem repeat profiling provides an international reference standard for human cell lines
Masters, J. R., Thomson, J. A., Daly-Burns, B., Reid, Y. A., Dirks, W. G., Packer, P., Toji, L. H., Ohno, T., Tanabe, H., Arlett, C. F., et al. (2001) · Proceedings of the National Academy of Sciences
Identification and Quantification in FoodForensic and Genetic Research
Cited by 478
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Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6
Kozak, M. (1997) · The EMBO Journal
RNA and protein synthesis mechanismsRNA Research and Splicing
Cited by 478
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Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes: Insights Into Molecular, Cellular, and Functional Phenotypes
Karakikes, I., Ameen, M., Termglinchan, V., & Wu, J. C. (2015) · Circulation Research
Pluripotent Stem Cells ResearchCongenital heart defects research
Cited by 478
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Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins
Turnbaugh, P. J., Quince, C., Faith, J. J., McHardy, A. C., Yatsunenko, T., Niazi, F., Affourtit, J., Egholm, M., Henrissat, B., Knight, R., et al. (2010) · Proceedings of the National Academy of Sciences
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 478
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Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest
Mills, R. J., Titmarsh, D. M., Koenig, X., Parker, B. L., Ryall, J. G., Quaife-Ryan, G. A., Voges, H. K., Hodson, M. P., Ferguson, C., Drowley, L., et al. (2017) · Proceedings of the National Academy of Sciences
Pluripotent Stem Cells ResearchCongenital heart defects research
Cited by 478
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Current applications and future perspective of CRISPR/Cas9 gene editing in cancer
Wang, S.-W., Gao, C., Zheng, Y.-M., Yi, L., Lu, J.-C., Huang, X.-Y., Cai, J.-B., Zhang, P.-F., Cui, Y.-H., & Ke, A.-W. (2022) · Molecular Cancer
CRISPR and Genetic EngineeringChromatin Remodeling and Cancer
Cited by 478
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Adrenoleukodystrophy: phenotype, genetics, pathogenesis and therapy
Moser, H. (1997) · Brain
Metabolism and Genetic DisordersAdrenal Hormones and Disorders
Cited by 478
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MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs
Gabisonia, K., Prosdocimo, G., Aquaro, G. D., Carlucci, L., Zentilin, L., Secco, I., Ali, H., Braga, L., Gorgodze, N., Bernini, F., et al. (2019) · Nature
Congenital heart defects researchCardiac Fibrosis and Remodeling
Cited by 478
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Induction of the LIM homeobox gene Lmx1 by WNT6a establishes dorsoventral pattern in the vertebrate limb
Riddle, R. D., Ensini, M., Nelson, C., Tsuchida, T., Jessell, T. M., & Tabin, C. (1995) · Cell
Developmental Biology and Gene RegulationWnt/β-catenin signaling in development and cancer
Cited by 478
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Molecular Pathways Controlling Heart Development
Olson, E. N., & Srivastava, D. (1996) · Science
Congenital heart defects researchDevelopmental Biology and Gene Regulation
Cited by 478
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The zinc-finger protein Zelda is a key activator of the early zygotic genome in Drosophila
Liang, H.-L., Nien, C.-Y., Liu, H.-Y., Metzstein, M. M., Kirov, N., & Rushlow, C. (2008) · Nature
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 478
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miR-21 plays a pivotal role in gastric cancer pathogenesis and progression
Zhang, Z., Li, Z., Gao, C., Chen, P., Chen, J., Liu, W., Xiao, S., & Lu, H. (2008) · Laboratory Investigation
MicroRNA in disease regulationHelicobacter pylori-related gastroenterology studies
Cited by 477
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Matrigel: From discovery and ECM mimicry to assays and models for cancer research
Benton, G., Arnaoutova, I., George, J., Kleinman, H. K., & Koblinski, J. (2014) · Advanced Drug Delivery Reviews
Cellular Mechanics and InteractionsHydrogels: synthesis, properties, applications
Cited by 477
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