Most cited biochemistry, genetics and molecular biology papers
- Verified
Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy
Bengtsson, N. E., Hall, J. K., Odom, G. L., Phelps, M. P., Andrus, C. R., Hawkins, R. D., Hauschka, S. D., Chamberlain, J. R., & Chamberlain, J. S. (2017) · Nature Communications
CRISPR and Genetic EngineeringVirus-based gene therapy research
Cited by 387
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Regulation of gene expression by alternative promoters
Ayoubi, T. A. Y., & Van De Yen, W. J. M. (1996) · The FASEB Journal
RNA Research and SplicingGenomics and Chromatin Dynamics
Cited by 387
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Precise plant genome editing using base editors and prime editors
Molla, K. A., Sretenovic, S., Bansal, K. C., & Qi, Y. (2021) · Nature Plants
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 387
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Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data
Shi, H., Kichaev, G., & Pasaniuc, B. (2016) · The American Journal of Human Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 387
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Inhibition of SIRT1 Reactivates Silenced Cancer Genes without Loss of Promoter DNA Hypermethylation
Pruitt, K., Zinn, R. L., Ohm, J. E., McGarvey, K. M., Kang, S.-H. L., Watkins, D. N., Herman, J. G., & Baylin, S. B. (2006) · PLoS Genetics
Epigenetics and DNA MethylationHistone Deacetylase Inhibitors Research
Cited by 387
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Robustly detecting differential expression in RNA sequencing data using observation weights
Zhou, X., Lindsay, H., & Robinson, M. D. (2014) · Nucleic Acids Research
Gene expression and cancer classificationGenomics and Phylogenetic Studies
Cited by 387
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Exosomes derived from hypoxia-preconditioned mesenchymal stromal cells ameliorate cognitive decline by rescuing synaptic dysfunction and regulating inflammatory responses in APP/PS1 mice
Cui, G., Wu, J., Mou, F., Xie, W., Wang, F., Wang, Q., Fang, J., Xu, Y., Dong, Y., Liu, J., et al. (2018) · The FASEB Journal
Extracellular vesicles in diseaseAlzheimer's disease research and treatments
Cited by 387
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Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
Dong, Z., Birrer, M. J., Watts, R. G., Matrisian, L. M., & Colburn, N. H. (1994) · Proceedings of the National Academy of Sciences
Protein Kinase Regulation and GTPase SignalingCarcinogens and Genotoxicity Assessment
Cited by 386
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Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo
Zhu, W., Xu, W., Jiang, R., Qian, H., Chen, M., Hu, J., Cao, W., Han, C., & Chen, Y. (2006) · Experimental and Molecular Pathology
Mesenchymal stem cell researchCancer Cells and Metastasis
Cited by 386
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Herpes Simplex Virus Type 1 Immediate-Early Protein ICP0 and Its Isolated RING Finger Domain Act as Ubiquitin E3 Ligases In Vitro
Boutell, C., Sadis, S., & Everett, R. D. (2002) · Journal of Virology
Ubiquitin and proteasome pathwaysHerpesvirus Infections and Treatments
Cited by 386
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tRNA fragments in human health and disease
Anderson, P., & Ivanov, P. (2014) · FEBS Letters
RNA modifications and cancerRNA and protein synthesis mechanisms
Cited by 386
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Double Strand Breaks Can Initiate Gene Silencing and SIRT1-Dependent Onset of DNA Methylation in an Exogenous Promoter CpG Island
O'Hagan, H. M., Mohammad, H. P., & Baylin, S. B. (2008) · PLoS Genetics
Epigenetics and DNA MethylationDNA Repair Mechanisms
Cited by 386
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GLYCOSYLATION IN THE NUCLEUS AND CYTOPLASM
Hart, G. W., Haltiwanger, R. S., Holt, G. D., & Kelly, W. G. (1989) · Annual Review of Biochemistry
Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis
Cited by 386
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The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk
Wang, D. D., Nguyen, L. H., Li, Y., Yan, Y., Ma, W., Rinott, E., Ivey, K. L., Shai, I., Willett, W. C., Hu, F. B., et al. (2021) · Nature Medicine
Gut microbiota and healthNutritional Studies and Diet
Cited by 386
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Integration of electrophysiological recordings with single-cell RNA-seq data identifies neuronal subtypes
Fuzik, J., Zeisel, A., Máté, Z., Calvigioni, D., Yanagawa, Y., Szabó, G., Linnarsson, S., & Harkany, T. (2016) · Nature Biotechnology
Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research
Cited by 386
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Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways
Igarashi, M., Wakasaki, H., Takahara, N., Ishii, H., Jiang, Z.-Y., Yamauchi, T., Kuboki, K., Meier, M., Rhodes, C. J., & King, G. L. (1999) · Journal of Clinical Investigation
Protein Kinase Regulation and GTPase SignalingAdvanced Glycation End Products research
Cited by 386
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Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin
Chan, S. W., Lim, C. J., Chong, Y. F., Pobbati, A. V., Huang, C., & Hong, W. (2011) · Journal of Biological Chemistry
Hippo pathway signaling and YAP/TAZMicrotubule and mitosis dynamics
Cited by 386
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Timing is everything: The when and how of environmentally induced changes in the epigenome of animals
Faulk, C., & Dolinoy, D. C. (2011) · Epigenetics
Epigenetics and DNA MethylationBirth, Development, and Health
Cited by 386
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The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy
Scherz-Shouval, R., Santagata, S., Mendillo, M. L., Sholl, L. M., Ben-Aharon, I., Beck, A. H., Dias-Santagata, D., Koeva, M., Stemmer, S. M., Whitesell, L., et al. (2014) · Cell
Heat shock proteins researchTGF-β signaling in diseases
Cited by 386
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Cell adaptation to a physiologically relevant ECM mimic with different viscoelastic properties
Ghosh, K., Pan, Z., Guan, E., Ge, S., Liu, Y., Nakamura, T., Ren, X.-D., Rafailovich, M., & Clark, R. A. F. (2007) · Biomaterials
Cellular Mechanics and InteractionsHydrogels: synthesis, properties, applications
Cited by 386
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Comparative Analysis of Transposable Elements Highlights Mobilome Diversity and Evolution in Vertebrates
Chalopin, D., Naville, M., Plard, F., Galiana, D., & Volff, J.-N. (2015) · Genome Biology and Evolution
Chromosomal and Genetic VariationsGenome Rearrangement Algorithms
Cited by 386
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Fibronectin Regulates Wnt7a Signaling and Satellite Cell Expansion
Bentzinger, C. F., Wang, Y. X., von Maltzahn, J., Soleimani, V. D., Yin, H., & Rudnicki, M. A. (2013) · Cell Stem Cell
Muscle Physiology and DisordersWnt/β-catenin signaling in development and cancer
Cited by 386
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Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-α-prolyl-4-hydroxylases
MARXSEN, J. H., STENGEL, P., DOEGE, K., HEIKKINEN, P., JOKILEHTO, T., WAGNER, T., JELKMANN, W., JAAKKOLA, P., & METZEN, E. (2004) · Biochemical Journal
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 386
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SPR-measured dissociation kinetics of PROTAC ternary complexes influence target degradation rate
Roy, M. J., Winkler, S., Hughes, S. J., Whitworth, C., Galant, M., Farnaby, W., Rumpel, K., & Ciulli, A. (2019) · ACS Chemical Biology
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 386
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