Most cited biochemistry, genetics and molecular biology papers
- Verified
Evidence for a piwi -Dependent RNA Silencing of the gypsy Endogenous Retrovirus by the Drosophila melanogaster flamenco Gene
Sarot, E., Payen-Groschêne, G., Bucheton, A., & Pélisson, A. (2004) · Genetics
Chromosomal and Genetic VariationsEpigenetics and DNA Methylation
Cited by 251
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Saccharomyces cerevisiae contains two functional genes encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Basson, M. E., Thorsness, M., & Rine, J. (1986) · Proceedings of the National Academy of Sciences
Fungal and yeast genetics researchCholesterol and Lipid Metabolism
Cited by 251
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Sodium Selenite Induces Superoxide-Mediated Mitochondrial Damage and Subsequent Autophagic Cell Death in Malignant Glioma Cells
Kim, E. H., Sohn, S., Kwon, H. J., Kim, S. U., Kim, M.-J., Lee, S.-J., & Choi, K. S. (2007) · Cancer Research
Autophagy in Disease and TherapyCell death mechanisms and regulation
Cited by 251
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Chromatin accessibility dynamics in a model of human forebrain development
Trevino, A. E., Sinnott-Armstrong, N., Andersen, J., Yoon, S.-J., Huber, N., Pritchard, J. K., Chang, H. Y., Greenleaf, W. J., & Pașca, S. P. (2020) · Science
Genomics and Chromatin DynamicsNeurogenesis and neuroplasticity mechanisms
Cited by 251
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Higher-order unfolding of satellite heterochromatin is a consistent and early event in cell senescence
Swanson, E. C., Manning, B., Zhang, H., & Lawrence, J. B. (2013) · Journal of Cell Biology
Telomeres, Telomerase, and SenescenceNuclear Structure and Function
Cited by 251
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Comprehensive review of CRISPR-based gene editing: Mechanisms, challenges, and applications in cancer therapy
Chehelgerdi, M., Chehelgerdi, M., Khorramian-Ghahfarokhi, M., Shafieizadeh, M., Mahmoudi, E., Eskandari, F., Rashidi, M., Arshi, A., & Mokhtari-Farsani, A. (2024) · Molecular Cancer
CRISPR and Genetic EngineeringCAR-T cell therapy research
Cited by 251
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Dynamic Change of Chromatin Conformation in Response to Hypoxia Enhances the Expression of GLUT3 (SLC2A3) by Cooperative Interaction of Hypoxia-Inducible Factor 1 and KDM3A
Mimura, I., Nangaku, M., Kanki, Y., Tsutsumi, S., Inoue, T., Kohro, T., Yamamoto, S., Fujita, T., Shimamura, T., Suehiro, J.-I., et al. (2012) · Molecular and Cellular Biology
Cancer, Hypoxia, and MetabolismGenomics and Chromatin Dynamics
Cited by 251
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Telomeres and lifestyle factors: Roles in cellular aging.
Lin, J., Epel, E., & Blackburn, E. (2012) · Mutation research. Fundamental and molecular mechanisms of mutagenesis
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 251
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Isolation of a Mutant Arabidopsis Plant That Lacks N-Acetyl Glucosaminyl Transferase I and Is Unable to Synthesize Golgi-Modified Complex N-Linked Glycans
von Schaewen, A., Sturm, A., O'Neill, J., & Chrispeels, M. J. (1993) · Plant Physiology
Glycosylation and Glycoproteins ResearchPolysaccharides and Plant Cell Walls
Cited by 251
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A Role for Noncoding Variation in Schizophrenia
Roussos, P., Mitchell, A. C., Voloudakis, G., Fullard, J. F., Pothula, V. M., Tsang, J., Stahl, E. A., Georgakopoulos, A., Ruderfer, D. M., Charney, A., et al. (2014) · Cell Reports
Genetic Associations and EpidemiologySchizophrenia research and treatment
Cited by 251
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Under cover: causes, effects and implications of Hsp90‐mediated genetic capacitance
Sangster, T. A., Lindquist, S., & Queitsch, C. (2004) · BioEssays
Heat shock proteins researchEvolution and Genetic Dynamics
Cited by 251
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Splicing-Dependent RNA Polymerase Pausing in Yeast
Alexander, R. D., Innocente, S. A., Barrass, J. D., & Beggs, J. D. (2010) · Molecular Cell
RNA Research and SplicingGenomics and Chromatin Dynamics
Cited by 251
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Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity
Imaide, S., Riching, K. M., Makukhin, N., Vetma, V., Whitworth, C., Hughes, S. J., Trainor, N., Mahan, S. D., Murphy, N., Cowan, A. D., et al. (2021) · Nature Chemical Biology
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 251
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ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis
Kim, Y.-M., Kim, S.-J., Tatsunami, R., Yamamura, H., Fukai, T., & Ushio-Fukai, M. (2017) · American Journal of Physiology-Cell Physiology
Redox biology and oxidative stressAngiogenesis and VEGF in Cancer
Cited by 251
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Elucidating the Folding Problem of Helical Peptides using Empirical Parameters. III>Temperature and pH Dependence
Muñoz, V., & Serrano, L. (1995) · Journal of Molecular Biology
Protein Structure and DynamicsChemical Synthesis and Analysis
Cited by 251
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Identification of six new susceptibility loci for invasive epithelial ovarian cancer
EMBRACE, Kuchenbaecker, K. B., Collaborators, G. S., Breast Cancer Family Registry, HEBON, KConFab Investigators, Australian Cancer Study (Ovarian Cancer Investigators), Australian Ovarian Cancer Study Group, the Consortium of Investigators of Modifiers of BRCA1 and BRCA2, Ramus, S. J., et al. (2015) · Nature Genetics
BRCA gene mutations in cancerOvarian cancer diagnosis and treatment
Cited by 250
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The hallmarks of fibroblast ageing
Tigges, J., Krutmann, J., Fritsche, E., Haendeler, J., Schaal, H., Fischer, J. W., Kalfalah, F., Reinke, H., Reifenberger, G., Stühler, K., et al. (2014) · Mechanisms of Ageing and Development
Telomeres, Telomerase, and SenescenceSkin Protection and Aging
Cited by 250
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HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy
Marcu, A., Bichmann, L., Kuchenbecker, L., Kowalewski, D. J., Freudenmann, L. K., Backert, L., Mühlenbruch, L., Szolek, A., Lübke, M., Wagner, P., et al. (2021) · Journal for ImmunoTherapy of Cancer
vaccines and immunoinformatics approachesImmunotherapy and Immune Responses
Cited by 250
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The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation
Yamamoto, T., Sekine, Y., Kashima, K., Kubota, A., Sato, N., Aoki, N., & Matsuda, T. (2002) · Biochemical and Biophysical Research Communications
Protein Tyrosine PhosphatasesCytokine Signaling Pathways and Interactions
Cited by 250
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Subcellular Organization of GPCR Signaling
Eichel, K., & von Zastrow, M. (2018) · Trends in Pharmacological Sciences
Receptor Mechanisms and SignalingCellular transport and secretion
Cited by 250
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Role of ESCRT-I in Retroviral Budding
Martin-Serrano, J., Zang, T., & Bieniasz, P. D. (2003) · Journal of Virology
Cellular transport and secretionHIV Research and Treatment
Cited by 250
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Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases
Gao, J., Wang, L., Liu, J., Xie, F., Su, B., & Wang, X. (2017) · Antioxidants
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 250
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Effects of IGF-1 isoforms on muscle growth and sarcopenia
Ascenzi, F., Barberi, L., Dobrowolny, G., Villa Nova Bacurau, A., Nicoletti, C., Rizzuto, E., Rosenthal, N., Scicchitano, B. M., & Musarò, A. (2019) · Aging Cell
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 250
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MITRAC Links Mitochondrial Protein Translocation to Respiratory-Chain Assembly and Translational Regulation
Mick, D. U., Dennerlein, S., Wiese, H., Reinhold, R., Pacheu-Grau, D., Lorenzi, I., Sasarman, F., Weraarpachai, W., Shoubridge, E. A., Warscheid, B., et al. (2012) · Cell
Mitochondrial Function and PathologyATP Synthase and ATPases Research
Cited by 250
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