Most cited biochemistry, genetics and molecular biology papers
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An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3′ mispaired DNA
Chou, K.-M., & Cheng, Y.-C. (2002) · Nature
DNA Repair MechanismsDNA and Nucleic Acid Chemistry
Cited by 239
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Calorie Restriction and Aging in Humans
Flanagan, E. W., Most, J., Mey, J. T., & Redman, L. M. (2020) · Annual Review of Nutrition
Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health
Cited by 239
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Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model
Smith, R. P., Taher, L., Patwardhan, R. P., Kim, M. J., Inoue, F., Shendure, J., Ovcharenko, I., & Ahituv, N. (2013) · Nature Genetics
Genomics and Chromatin DynamicsGene Regulatory Network Analysis
Cited by 239
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Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications.
Hartman, Z. C., Appledorn, D. M., & Amalfitano, A. (2008) · Virus Research
Virus-based gene therapy researchImmunotherapy and Immune Responses
Cited by 239
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Using the “reverse Warburg effect” to identify high-risk breast cancer patients: Stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers
Witkiewicz, A. K., Whitaker-Menezes, D., Dasgupta, A., Philp, N. J., Lin, Z., Gandara, R., Sneddon, S., Martinez-Outschoorn, U. E., Sotgia, F., & Lisanti, M. P. (2012) · Cell Cycle
Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis
Cited by 239
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Phenazine-1-carboxylic acid promotes bacterial biofilm development via ferrous iron acquisition
Wang, Y., Wilks, J. C., Danhorn, T., Ramos, I., Croal, L., & Newman, D. K. (2011) · Journal of Bacteriology
Bacterial biofilms and quorum sensingBacterial Genetics and Biotechnology
Cited by 239
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VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400
Young, A. P., Schlisio, S., Minamishima, Y. A., Zhang, Q., Li, L., Grisanzio, C., Signoretti, S., & Kaelin, W. G. (2008) · Nature Cell Biology
Telomeres, Telomerase, and SenescenceCancer, Hypoxia, and Metabolism
Cited by 239
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Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A
Wong, P.-M., Feng, Y., Wang, J., Shi, R., & Jiang, X. (2015) · Nature Communications
Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer
Cited by 239
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Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons
Smrt, R. D., Eaves-Egenes, J., Barkho, B. Z., Santistevan, N. J., Zhao, C., Aimone, J. B., Gage, F. H., & Zhao, X. (2007) · Neurobiology of Disease
Genetics and Neurodevelopmental DisordersNeurogenesis and neuroplasticity mechanisms
Cited by 239
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Gli Protein Activity Is Controlled by Multisite Phosphorylation in Vertebrate Hedgehog Signaling
Niewiadomski, P., Kong, J. H., Ahrends, R., Ma, Y., Humke, E. W., Khan, S., Teruel, M. N., Novitch, B. G., & Rohatgi, R. (2014) · Cell Reports
Hedgehog Signaling Pathway StudiesWnt/β-catenin signaling in development and cancer
Cited by 239
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Subcellular localization of hexokinases I and II directs the metabolic fate of glucose
John, S., Weiss, J. N., & Ribalet, B. (2011) · PLoS ONE
Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus
Cited by 239
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Chance and necessity in the evolution of minimal metabolic networks
Pál, C., Papp, B., Lercher, M. J., Csermely, P., Oliver, S. G., & Hurst, L. D. (2006) · Nature
Microbial Metabolic Engineering and BioproductionEvolution and Genetic Dynamics
Cited by 239
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The role of inflammation in age-related disease
Howcroft, T. K., Campisi, J., Louis, G. B., Smith, M. T., Wise, B., Wyss-Coray, T., Augustine, A. D., McElhaney, J. E., Kohanski, R., & Sierra, F. (2013) · Aging
Genetics, Aging, and Longevity in Model OrganismsImmune Response and Inflammation
Cited by 239
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Reduced Expression of Connective Tissue Growth Factor (CTGF/CCN2) Mediates Collagen Loss in Chronologically Aged Human Skin
Quan, T., Shao, Y., He, T., Voorhees, J. J., & Fisher, G. J. (2010) · Journal of Investigative Dermatology
Connective Tissue Growth Factor ResearchSkin Protection and Aging
Cited by 239
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Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis
Xu, J., Jiang, Y., Wang, J., Shi, X., Liu, Q., Liu, Z., Li, Y., Scott, M. J., Xiao, G., Li, S., et al. (2014) · Cell Death & Differentiation
Inflammasome and immune disordersAdvanced Glycation End Products research
Cited by 239
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Sustained miRNA delivery from an injectable hydrogel promotes cardiomyocyte proliferation and functional regeneration after ischaemic injury
Wang, L. L., Liu, Y., Chung, J. J., Wang, T., Gaffey, A. C., Lu, M., Cavanaugh, C. A., Zhou, S., Kanade, R., Atluri, P., et al. (2017) · Nature Biomedical Engineering
Congenital heart defects researchTissue Engineering and Regenerative Medicine
Cited by 239
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Glucose, Glycation, and RAGE: Implications for Amplification of Cellular Dysfunction in Diabetic Nephropathy
Wendt, T., Tanji, N., Guo, J., Hudson, B. I., Bierhaus, A., Ramasamy, R., Arnold, B., Nawroth, P. P., Yan, S. F., D’Agati, V., et al. (2003) · Journal of the American Society of Nephrology
Advanced Glycation End Products researchChronic Kidney Disease and Diabetes
Cited by 239
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Thinking about genetic redundancy
Thomas, J. H. (1993) · Trends in Genetics
Evolution and Genetic DynamicsChromosomal and Genetic Variations
Cited by 239
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Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis
Werner, C., Hanhoun, M., Widmann, T., Kazakov, A., Semenov, A., Pöss, J., Bauersachs, J., Thum, T., Pfreundschuh, M., Müller, P., et al. (2008) · Journal of the American College of Cardiology
Telomeres, Telomerase, and SenescenceCardiovascular Effects of Exercise
Cited by 239
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DNA methylation dynamics during early plant life
Bouyer, D., Kramdi, A., Kassam, M., Heese, M., Schnittger, A., Roudier, F., & Colot, V. (2017) · Genome Biology
Epigenetics and DNA MethylationPlant Molecular Biology Research
Cited by 239
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Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration
Petersen, C. P., & Reddien, P. W. (2011) · Science
Planarian Biology and ElectrostimulationWnt/β-catenin signaling in development and cancer
Cited by 239
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The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway
Pasquinelli, A. E., Ernst, R. K., Lund, E., Grimm, C., Zapp, M. L., Rekosh, D., Hammarskjöld, M., & Dahlberg, J. E. (1997) · The EMBO Journal
RNA Research and SplicingNuclear Structure and Function
Cited by 239
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Kinesin ATPase: rate-limiting ADP release
Hackney, D. D. (1988) · Proceedings of the National Academy of Sciences
Microtubule and mitosis dynamicsATP Synthase and ATPases Research
Cited by 239
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Carbonic Anhydrase IX Promotes Tumor Growth and Necrosis In Vivo and Inhibition Enhances Anti-VEGF Therapy
McIntyre, A., Patiar, S., Wigfield, S., Li, J.-L., Ledaki, I., Turley, H., Leek, R., Snell, C., Gatter, K., Sly, W. S., et al. (2012) · Clinical Cancer Research
Enzyme function and inhibitionCancer, Hypoxia, and Metabolism
Cited by 239
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