Most cited medicine papers
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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H., & Johansen, T. (2005) · The Journal of Cell Biology
Autophagy in Disease and TherapyGenetic Neurodegenerative Diseases
Cited by 3,276
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The measurement of clinical pain intensity: a comparison of six methods
Jensen, M. P., Karoly, P., & Braver, S. (1986) · Pain
Pain Management and Opioid UseMusculoskeletal pain and rehabilitation
Cited by 3,275
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Cancer Statistics, 2003
Jemal, A., Murray, T., Samuels, A., Ghafoor, A., Ward, E., & Thun, M. J. (2003) · CA: A Cancer Journal for Clinicians
Global Cancer Incidence and ScreeningColorectal Cancer Screening and Detection
Cited by 3,275
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Mechanisms of mitophagy
Youle, R. J., & Narendra, D. P. (2011) · Nature Reviews Molecular Cell Biology
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments
Cited by 3,273
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Principles of interleukin (IL)-6-type cytokine signalling and its regulation
HEINRICH, P. C., BEHRMANN, I., HAAN, S., HERMANNS, H. M., MÜLLER-NEWEN, G., & SCHAPER, F. (2003) · Biochemical Journal
Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases
Cited by 3,272
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Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
Douillard, J., Cunningham, D., Roth, A., Navarro, M., James, R., Karasek, P., Jandik, P., Iveson, T., Carmichael, J., Alakl, M., et al. (2000) · The Lancet
Colorectal Cancer Treatments and StudiesColorectal Cancer Surgical Treatments
Cited by 3,256
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Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia
Fielding, R. A., Vellas, B., Evans, W. J., Bhasin, S., Morley, J. E., Newman, A. B., Abellan van Kan, G., Andrieu, S., Bauer, J., Breuille, D., et al. (2011) · Journal of the American Medical Directors Association
Nutrition and Health in AgingFrailty in Older Adults
Cited by 3,256
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Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.
Baeten, J. M., Donnell, D., Ndase, P., Mugo, N. R., Campbell, J. D., Wangisi, J., Tappero, J. W., Bukusi, E. A., Cohen, C. R., Katabira, E., et al. (2012) · New England Journal of Medicine
HIV/AIDS Research and InterventionsHIV/AIDS drug development and treatment
Cited by 3,256
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Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis
Bellamy, L., Casas, J.-P., Hingorani, A. D., & Williams, D. (2009) · The Lancet
Gestational Diabetes Research and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 3,253
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Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline
Kapur, V. K., Auckley, D. H., Chowdhuri, S., Kuhlmann, D. C., Mehra, R., Ramar, K., & Harrod, C. G. (2017) · Journal of Clinical Sleep Medicine
Obstructive Sleep Apnea ResearchSleep and related disorders
Cited by 3,253
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What is ‘quality of evidence’ and why is it important to clinicians?
Guyatt, G. H., Oxman, A. D., Kunz, R., Vist, G. E., Falck-Ytter, Y., & Schünemann, H. J. (2008) · BMJ
Clinical practice guidelines implementationMeta-analysis and systematic reviews
Cited by 3,250
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Stool form scale as a useful guide to intestinal transit time
Lewis, S. J., & Heaton, K. W. (1997) · Scandinavian Journal of Gastroenterology
Gastrointestinal motility and disordersPelvic floor disorders treatments
Cited by 3,244
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The Self-Medication Hypothesis of Substance Use Disorders: A Reconsideration and Recent Applications
Khantzian, E. J. (1997) · Harvard Review of Psychiatry
Substance Abuse Treatment and OutcomesGambling Behavior and Treatments
Cited by 3,242
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Naturally occurring antibodies devoid of light chains
Hamers-Casterman, C., Atarhouch, T., Muyldermans, S., Robinson, G., Hammers, C., Songa, E. B., Bendahman, N., & Hammers, R. (1993) · Nature
Monoclonal and Polyclonal Antibodies ResearchAnimal Diversity and Health Studies
Cited by 3,241
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Too far to walk: Maternal mortality in context
Thaddeus, S., & Maine, D. (1994) · Social Science & Medicine
Global Maternal and Child HealthMaternal and fetal healthcare
Cited by 3,240
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A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis
Lennon, V. A., Wingerchuk, D. M., Kryzer, T. J., Pittock, S. J., Lucchinetti, C. F., Fujihara, K., Nakashima, I., & Weinshenker, B. G. (2004) · The Lancet
Multiple Sclerosis Research StudiesAutoimmune Neurological Disorders and Treatments
Cited by 3,239
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Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: A population-based study
Prado, C. M., Lieffers, J. R., McCargar, L. J., Reiman, T., Sawyer, M. B., Martin, L., & Baracos, V. E. (2008) · The Lancet Oncology
Nutrition and Health in AgingBody Composition Measurement Techniques
Cited by 3,238
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Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
Zaretsky, J. M., Garcia-Diaz, A., Shin, D. S., Escuin-Ordinas, H., Hugo, W., Hu-Lieskovan, S., Torrejon, D. Y., Abril-Rodriguez, G., Sandoval, S., Barthly, L., et al. (2016) · New England Journal of Medicine
Cancer Immunotherapy and BiomarkersCutaneous Melanoma Detection and Management
Cited by 3,237
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Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease
Seshadri, S., Beiser, A., Selhub, J., Jacques, P. F., Rosenberg, I. H., D'Agostino, R. B., Wilson, P. W. F., & Wolf, P. A. (2002) · New England Journal of Medicine
Folate and B Vitamins ResearchDementia and Cognitive Impairment Research
Cited by 3,237
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2021 guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association/American Stroke Association
Kleindorfer, D. O., Towfighi, A., Chaturvedi, S., Cockroft, K. M., Gutierrez, J., Lombardi-Hill, D., Kamel, H., Kernan, W. N., Kittner, S. J., Leira, E. C., et al. (2021) · Stroke
Acute Ischemic Stroke ManagementCerebrovascular and Carotid Artery Diseases
Cited by 3,237
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An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
Jackson, L. A., Anderson, E. J., Rouphael, N. G., Roberts, P. C., Makhene, M., Coler, R. N., McCullough, M. P., Chappell, J. D., Denison, M. R., Stevens, L. J., et al. (2020) · New England Journal of Medicine
SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies
Cited by 3,237
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Oral Rivaroxaban for Symptomatic Venous Thromboembolism
The EINSTEIN Investigators (2010) · New England Journal of Medicine
Venous Thromboembolism Diagnosis and ManagementBlood Coagulation and Thrombosis Mechanisms
Cited by 3,237
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Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
Lincoff, A. M., Brown-Frandsen, K., Colhoun, H. M., Deanfield, J., Emerson, S. S., Esbjerg, S., Hardt-Lindberg, S., Hovingh, G. K., Kahn, S. E., Kushner, R. F., et al. (2023) · New England Journal of Medicine
Diabetes Treatment and ManagementPharmacology and Obesity Treatment
Cited by 3,236
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Use of proteomic patterns in serum to identify ovarian cancer
Petricoin, E. F., Ardekani, A. M., Hitt, B. A., Levine, P. J., Fusaro, V. A., Steinberg, S. M., Mills, G. B., Simone, C., Fishman, D. A., Kohn, E. C., et al. (2002) · The Lancet
Ovarian cancer diagnosis and treatmentAdvanced Proteomics Techniques and Applications
Cited by 3,236
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