Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
In Vitro to in Vivo Extrapolation and Physiologically Based Modeling of Cytochrome P450 Mediated Metabolism in Beagle Dog Gut Wall and Liver
Heikkinen, A. T., Fowler, S., Gray, L., Li, J., Peng, Y., Yadava, P., Railkar, A., & Parrott, N. (2013) · Molecular Pharmaceutics
Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices
Cited by 20
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Effect of the administration of Psidium guava leaves on blood glucose, lipid profiles and sensitivity of the vascular mesenteric bed to Phenylephrine in streptozotocin-induced diabetic rats
Bahrani, A. H. M., Zaheri, H., Soltani, N., Kharazmi, F., Keshavarz, M., & Kamalinajad, M. (2012) · Journal of Diabetes Mellitus
Psidium guajava Extracts and ApplicationsNatural Antidiabetic Agents Studies
Cited by 20
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Propylthiouracyl-induced severe liver toxicity: An indication for alanine aminotransferase monitoring
Benyounes, M. (2006) · World Journal of Gastroenterology
Drug-Induced Hepatotoxicity and ProtectionPharmacovigilance and Adverse Drug Reactions
Cited by 20
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Fragment-based lead generation: identification of seed fragments by a highly efficient fragment screening technology
Neumann, L., Ritscher, A., Müller, G., & Hafenbradl, D. (2009) · Journal of Computer-Aided Molecular Design
Computational Drug Discovery MethodsChemical Synthesis and Analysis
Cited by 20
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Expression and genotype-dependent catalytic activity of N-acetyltransferase 2 (NAT2) in human peripheral blood mononuclear cells and its modulation by Sirtuin 1
Salazar-González, R. A., Turiján-Espinoza, E., Hein, D. W., Milán-Segovia, R. C., Uresti-Rivera, E. E., & Portales-Pérez, D. P. (2018) · Biochemical Pharmacology
Pharmacogenetics and Drug MetabolismGlutathione Transferases and Polymorphisms
Cited by 20
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CYP2C19 and CYP2D6 genotypes in Pacific peoples
Helsby, N. A. (2016) · British Journal of Clinical Pharmacology
Pharmacogenetics and Drug MetabolismAntiplatelet Therapy and Cardiovascular Diseases
Cited by 20
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Computational modeling and biological validation of novel non-steroidal ligands for the cholesterol recognition/interaction amino acid consensus (CRAC) motif of the mitochondrial translocator protein (TSPO)
Midzak, A. S., Akula, N., Rone, M. B., & Papadopoulos, V. (2015) · Pharmacological Research
Computational Drug Discovery MethodsPharmacological Receptor Mechanisms and Effects
Cited by 20
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Sulfasalazine reduces bile acid induced apoptosis in human hepatoma cells and perfused rat livers
Rust, C., Bauchmuller, K., Bernt, C., Vennegeerts, T., Fickert, P., Fuchsbichler, A., & Beuers, U. (2006) · Gut
Drug-Induced Hepatotoxicity and ProtectionDrug Transport and Resistance Mechanisms
Cited by 20
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Control of drug release from microparticles by tuning their crystalline textures: A structure–activity study
Miles, C. E., Bernstein, A. D., Osborn Popp, T. M., Murthy, N. S., Nieuwkoop, A. J., & Gormley, A. J. (2021) · ACS Applied Polymer Materials
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 20
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Efficacy and Safety of Armolipid Plus®: An Updated PRISMA Compliant Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Cicero, A. F. G., Kennedy, C., Knežević, T., Bove, M., Georges, C. M. G., Šatrauskienė, A., Toth, P. P., & Fogacci, F. (2021) · Nutrients
Natural Products and Biological ResearchLipoproteins and Cardiovascular Health
Cited by 20
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Invasive alien plant impacts on human health and well-being.
Lazzaro, L., Essl, F., Lugliè, A., Padedda, B. M., Pyšek, P., & Brundu, G. (2018) · Invasive species and human health
Plant Toxicity and Pharmacological PropertiesEcology and Vegetation Dynamics Studies
Cited by 20
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Evaluation of drug-induced liver injury as etiology for acute liver failure in Brazil
Santos, G., Figueira, E. R. R., D’Albuquerque, L. A. C., Lisboa, P. B., de Almeida, M. D., Filgueira, N. A., Boin, I., Porta, G., da Silva, R. D. C. M. A., Viana, C. F. G., et al. (2021) · Annals of Hepatology
Drug-Induced Hepatotoxicity and ProtectionLiver Disease and Transplantation
Cited by 20
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Use of Preclinical Dog Studies and Absorption Modeling to Facilitate Late Stage Formulation Bridging for a BCS II Drug Candidate
Kesisoglou, F. (2014) · AAPS PharmSciTech
Drug Solubulity and Delivery SystemsPharmaceutical studies and practices
Cited by 20
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Drug-induced liver injury. Part I: Classification, diagnosis and treatment
Kozielewicz, D. M., Stalke, P., & Skrzypek, J. (2025) · Clinical and Experimental Hepatology
Drug-Induced Hepatotoxicity and ProtectionPharmacovigilance and Adverse Drug Reactions
Cited by 19
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Agreement Among Different Scales for Causality Assessment in Drug-Induced Liver Injury
Das, S., Behera, S. K., Xavier, A. S., Velupula, S., Dkhar, S. A., & Selvarajan, S. (2018) · Clinical Drug Investigation
Drug-Induced Hepatotoxicity and ProtectionPharmacovigilance and Adverse Drug Reactions
Cited by 19
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Extension of the Mechanistic Tissue Distribution Model of Rodgers and Rowland by Systematic Incorporation of Lysosomal Trapping: Impact on Unbound Partition Coefficient and Volume of Distribution Predictions in the Rat
Schmitt, M. V., Reichel, A., Liu, X., Fricker, G., & Lienau, P. (2021) · Drug Metabolism and Disposition
Computational Drug Discovery MethodsPharmacogenetics and Drug Metabolism
Cited by 19
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Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2-/- but not in c-Jun N-terminal kinase 1−/− mice
Wang, X., Wu, D., Yang, L., & Cederbaum, A. I. (2011) · Hepatology
Drug-Induced Hepatotoxicity and ProtectionAlcohol Consumption and Health Effects
Cited by 19
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Elucidating the harm potential of brorphine analogues as new synthetic opioids: Synthesis, in vitro, and in vivo characterization
Vandeputte, M. M., Bilel, S., Tirri, M., Corli, G., Bassi, M., Layle, N. K., Fantinati, A., Walther, D., Iula, D. M., Baumann, M. H., et al. (2024) · Neuropharmacology
Forensic Toxicology and Drug AnalysisAlkaloids: synthesis and pharmacology
Cited by 19
- Verified
Synthetic Illicit Opioids in Brazil: Nitazenes Arrival
Gonçalves de Araújo, K. R., Fabris, A. L., Junior, L. F. N., Soares, A. L., Costa, J. L., & Yonamine, M. (2024) · Forensic Science International Reports
Forensic Toxicology and Drug AnalysisCrime, Illicit Activities, and Governance
Cited by 19
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The emergence of nitazenes: a new chapter in the synthetic opioid crisis
Caprari, C., Ferri, E., Rossetti, P., Gregori, A., Citti, C., & Cannazza, G. (2025) · Archives of Toxicology
Forensic Toxicology and Drug AnalysisOpioid Use Disorder Treatment
Cited by 19
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Caffeoyl malic acid is a potential dual inhibitor targeting TNFα/IL-4 evaluated by a combination strategy of network analysis-deep learning-molecular simulation
Wang, Y., Qin, D., Jin, L., & Liang, G. (2022) · Computers in Biology and Medicine
Computational Drug Discovery MethodsProtein Interaction Studies and Fluorescence Analysis
Cited by 19
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Transesterification ofp-hydroxybenzoate esters (parabens) by human intestinal (Caco-2) cells
Lakeram, M., Paine, A. J., Lockley, D. J., Sanders, D. J., Pendlington, R., & Forbes, B. (2006) · Xenobiotica
Pharmacogenetics and Drug MetabolismDrug Solubulity and Delivery Systems
Cited by 19
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Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats
Stiborová, M., Dračínská, H., Bořek-Dohalská, L., Klusoňová, Z., Holecová, J., Martínková, M., Schmeiser, H. H., & Arlt, V. M. (2018) · Toxicology
Pharmacogenetics and Drug MetabolismToxic Organic Pollutants Impact
Cited by 19
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An investigation into the influence of experimental conditions on in vitro drug release from immediate-release tablets of levothyroxine sodium and its relation to oral bioavailability
Kocic, I., Homsek, I., Dacevic, M., Parojcic, J., & Miljkovic, B. (2011) · AAPS PharmSciTech
Drug Solubulity and Delivery SystemsAnalytical Methods in Pharmaceuticals
Cited by 19
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