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The Aging Brain and Cognition: Contribution of Vascular Injury and Aβ to Mild Cognitive Dysfunction
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Vascular brain injury may predict cognitive outcome better than amyloid β deposition.
“Vascular brain injury may predict cognitive outcome better than amyloid β deposition (Marchant et al., 2013).”
From Apolipoprotein E–low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner (2014) · cites this paper as Marchant et al., 2013
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Albert, M. S., DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., Gamst, A., Holtzman, D. M., Jagust, W. J., Petersen, R. C., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.008 · Cited by 10,152
Self-citationHypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
Jack, C. R., Knopman, D. S., Jagust, W. J., Shaw, L. M., Aisen, P. S., Weiner, M. W., Petersen, R. C., & Trojanowski, J. Q. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70299-6 · Cited by 4,806
Self-citationSilent Brain Infarcts and the Risk of Dementia and Cognitive Decline
Vermeer, S. E., Prins, N. D., den Heijer, T., Hofman, A., Koudstaal, P. J., & Breteler, M. M. B. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022066 · Cited by 2,313
Mixed brain pathologies account for most dementia cases in community-dwelling older persons
Schneider, J. A., Arvanitakis, Z., Bang, W., & Bennett, D. A. (2007) · Neurology · doi:10.1212/01.wnl.0000271090.28148.24 · Cited by 1,992
Neuropathology of older persons without cognitive impairment from two community-based studies
Bennett, D. A., Schneider, J. A., Arvanitakis, Z., Kelly, J. F., Aggarwal, N. T., Shah, R. C., & Wilson, R. S. (2006) · Neurology · doi:10.1212/01.wnl.0000219668.47116.e6 · Cited by 1,336
Imaging β-amyloid burden in aging and dementia
Rowe, C. C., Ng, S., Ackermann, U., Gong, S. J., Pike, K., Savage, G., Cowie, T. F., Dickinson, K. L., Maruff, P., Darby, D., et al. (2007) · Neurology · doi:10.1212/01.wnl.0000261919.22630.ea · Cited by 1,104
Age, Neuropathology, and Dementia
Savva, G. M., Wharton, S. B., Ince, P. G., Forster, G., Matthews, F. E., & Brayne, C. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0806142 · Cited by 900
Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease
Villemagne, V. L., Pike, K. E., Chételat, G., Ellis, K. A., Mulligan, R. S., Bourgeat, P., Ackermann, U., Jones, G., Szoeke, C., Salvado, O., et al. (2011) · Annals of Neurology · doi:10.1002/ana.22248 · Cited by 833
Morris, J. C., Roe, C. M., Grant, E. A., Head, D., Storandt, M., Goate, A. M., Fagan, A. M., Holtzman, D. M., & Mintun, M. A. (2009) · Archives of Neurology · doi:10.1001/archneurol.2009.269 · Cited by 476
Zhang, X., Zhou, K., Wang, R., Cui, J., Lipton, S. A., Liao, F.-F., Xu, H., & Zhang, Y.-W. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m608856200 · Cited by 436
β-Amyloid burden in healthy aging: Regional distribution and cognitive consequences
Rodrigue, K. M., Kennedy, K. M., Devous, M. D., Rieck, J. R., Hebrank, A. C., Diaz-Arrastia, R., Mathews, D., & Park, D. C. (2012) · Neurology · doi:10.1212/wnl.0b013e318245d295 · Cited by 419
Cerebrovascular disease, beta-amyloid, and cognition in aging
Marchant, N. L., Reed, B. R., DeCarli, C. S., Madison, C. M., Weiner, M. W., Chui, H. C., & Jagust, W. J. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.10.001 · Cited by 127
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Flagged first, then by citations
Research works printed but not linked: 34
- [3]McKhann GM Knopman DS Chertkow H The diagnosis of dementia due to Alzheimer’s disease: recommendations from the National Institute on Aging–Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease Alzheimers Dement 2011 7 3 263 269 21514250 PMC3312024
- [4]Mintun MA Larossa GN Sheline YI [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease Neurology 2006 67 3 446 452 16894106
- [6]Hardy J Selkoe DJ The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics Science 2002 297 5580 353 356 12130773
- [8]Galvin JE Powlishta KK Wilkins K Predictors of preclinical Alzheimer disease and dementia: a clinicopathologic study Arch Neurol 2005 62 5 758 765 15883263
- [10]Prohovnik I Perl DP Davis KL Libow L Lesser G Haroutunian V Dissociation of neuropathology from severity of dementia in late-onset Alzheimer disease Neurology 2006 66 1 49 55 16401845
- [12]Rentz DM Locascio JJ Becker JA Cognition, reserve, and amyloid deposition in normal aging Ann Neurol 2010 67 3 353 364 20373347 PMC3074985
- [13]Storandt M Mintun MA Head D Morris JC Cognitive decline and brain volume loss as signatures of cerebral amyloid-3 peptide deposition identified with Pitts-burgh compound B: cognitive decline associated with Aβ deposition Arch Neurol 2009 66 12 1476 1481 20008651 PMC2796577
- [14]Resnick SM Sojkova J Zhou Y Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB Neurology 2010 74 10 807 815 20147655 PMC2839197
- [17]Lee JH Kim SH Kim GH Identification of pure subcortical vascular dementia using 11C-Pittsburgh compound B Neurology 2011 77 1 18 25 21593437
- [18]Hedden T Van Dijk KR Shire EH Sperling RA Johnson KA Buckner RL Failure to modulate attentional control in advanced aging linked to white matter pathology Cereb Cortex 2012 22 5 1038 1051 21765181 PMC3328340
- [19]Reed BR Mungas DM Kramer JH Profiles of neuropsychological impairment in autopsy-defined Alzheimer’s disease and cerebrovascular disease Brain 2007 130 pt 3 731 739 17267522
- [20]Troncoso JC Zonderman AB Resnick SM Crain B Pletnikova O O’Brien RJ Effect of infarcts on dementia in the Baltimore Longitudinal Study of Aging Ann Neurol 2008 64 2 168 176 18496870 PMC2694129
- [21]Mungas D Reed BR Kramer JH Psychometrically matched measures of global cognition, memory, and executive function for assessment of cognitive decline in older persons Neuropsychology 2003 17 3 380 392 12959504
- [22]Mormino EC Kluth JT Madison CM Alzheimer’s Disease Neuroimaging Initiative. Episodic memory loss is related to hippocampal-mediated 3-amyloid deposition in elderly subjects Brain 2009 132 pt 5 1310 1323 19042931 PMC2677792
- [23]Hadjidemetriou S Studholme C Mueller S Weiner M Schuff N Restoration of MRI data for intensity non-uniformities using local high order intensity statistics Med Image Anal 2009 13 1 36 48 18621568 PMC2597709
- [24]Hadjidemetriou S Lorenzen P Schuff N Mueller S Weiner M Computational atlases of severity of white matter lesions in elderly subjects with MRI Med Image Comput Comput Assist Interv 2008 11 pt 1 450 458 18979778
- [25]Mathalon DH Sullivan EV Rawles JM Pfefferbaum A Correction for head size in brain-imaging measurements Psychiatry Res 1993 50 2 121 139 8378488
- [26]Mathis CA Wang Y Holt DP Huang GF Debnath ML Klunk WE Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents J Med Chem 2003 46 13 2740 2754 12801237
- [27]Price JC Klunk WE Lopresti BJ Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B J Cereb Blood Flow Metab 2005 25 11 1528 1547 15944649
- [28]Logan J Fowler JS Volkow ND Wang GJ Ding YS Alexoff DL Distribution volume ratios without blood sampling from graphical analysis of PET data J Cereb Blood Flow Metab 1996 16 5 834 840 8784228
- [29]Rabinovici GD Furst AJ Alkalay A Increased metabolic vulnerability in early-onset Alzheimer’s disease is not related to amyloid burden Brain 2010 133 pt 2 512 528 20080878 PMC2858015
- [30]Newman AB Fitzpatrick AL Lopez O Dementia and Alzheimer’s disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort J Am Geriatr Soc 2005 53 7 1101 1107 16108925
- [31]Riekse RG Leverenz JB McCormick W Effect of vascular lesions on cognition in Alzheimer’s disease: a community-based study J Am Geriatr Soc 2004 52 9 1442 1448 15341544 PMC1487184
- [32]Snowdon DA Greiner LH Mortimer JA Riley KP Greiner PA Markesbery WR Brain infarction and the clinical expression of Alzheimer disease: the Nun Study JAMA 1997 277 10 813 817 9052711
- [33]Jellinger KA Attems J Prevalence of dementia disorders in the oldest-old: an autopsy study Acta Neuropathol 2010 119 4 421 433 20204386
- [35]Brickman AM Siedlecki KL Muraskin J White matter hyperintensities and cognition: testing the reserve hypothesis Neurobiol Aging 2011 32 9 1588 1598 19926168 PMC2891625
- [36]Salthouse TA Neuroanatomical substrates of age-related cognitive decline Psychol Bull 2011 137 5 753 784 21463028 PMC3132227
- [39]Pike KE Savage G Villemagne VL 3-Amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer’s disease Brain 2007 130 pt 11 2837 2844 17928318
- [40]Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales Lancet 2001 357 9251 169 175 11213093
- [41]Reed BR Marchant NL Jagust WJ Decarli CC Mack W Chui HC Coronary risk correlates with cerebral amyloid deposition Neurobiol Aging 2012 33 9 1979 1987 22078485 PMC3371309
- [42]Pluta R Ulamek M Jabłoński M Alzheimer’s mechanisms in ischemic brain degeneration Anat Rec (Hoboken) 2009 292 12 1863 1881 19943340
- [44]Chui HC Zheng L Reed BR Vinters HV Mack WJ Vascular risk factors and Alzheimer’s disease: are these risk factors for plaques and tangles or for concomitant vascular pathology that increases the likelihood of dementia? an evidence-based review Alzheimers Res Ther 2012 3 6 36 PMC3471388 22182734
- [45]Okello A Koivunen J Edison P Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study Neurology 2009 73 10 754 760 19587325 PMC2830881
- [46]Sagare AP Bell RD Zlokovic BV Neurovascular defects and faulty amyloid-3 vascular clearance in Alzheimer’s disease [published online June 29, 2012] J Alzheimers Dis 10.3233/JAD-2012-129037 PMC4416477 22751174 · DOI
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Impact of multiple pathologies on the threshold for clinically overt dementia
Kapasi, A., DeCarli, C., & Schneider, J. A. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1717-7 · Cited by 739
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Gottesman, R. F., Schneider, A. L. C., Zhou, Y., Coresh, J., Green, E., Gupta, N., Knopman, D. S., Mintz, A., Rahmim, A., Sharrett, A. R., et al. (2017) · JAMA · doi:10.1001/jama.2017.3090 · Cited by 650
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Boyle, P. A., Wilson, R. S., Yu, L., Barr, A. M., Honer, W. G., Schneider, J. A., & Bennett, D. A. (2013) · Annals of Neurology · doi:10.1002/ana.23964 · Cited by 323
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Propson, N. E., Roy, E. R., Litvinchuk, A., Köhl, J., & Zheng, H. (2021) · Journal of Clinical Investigation · doi:10.1172/jci140966 · Cited by 258
Rabin, J. S., Schultz, A. P., Hedden, T., Viswanathan, A., Marshall, G. A., Kilpatrick, E., Klein, H., Buckley, R. F., Yang, H.-S., Properzi, M., et al. (2018) · JAMA Neurology · doi:10.1001/jamaneurol.2018.1123 · Cited by 221
Fernando, W. M. A. D. B., Martins, I. J., Morici, M., Bharadwaj, P., Rainey-Smith, S. R., Lim, W. L. F., & Martins, R. N. (2020) · Journal of Alzheimer's Disease · doi:10.3233/jad-190120 · Cited by 164
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van Westen, D., Lindqvist, D., Blennow, K., Minthon, L., Nägga, K., Stomrud, E., Zetterberg, H., & Hansson, O. (2016) · Scientific Reports · doi:10.1038/srep20709 · Cited by 66
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“The present moderation analysis provides evidence of an additive effect of WMHs and Aβ in relation to baseline cognitive performance, which is consistent with the findings from other cross-section biomarker studies [6,9,10,42].”
Result
Metadata
- Authors
- Marchant, N. L., Reed, B. R., Sanossian, N., Madison, C. M., Kriger, S., Dhada, R., Mack, W. J., DeCarli, C., Weiner, M. W., Mungas, D. M., Chui, H. C., & Jagust, W. J.
- Venue
- JAMA Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 2013-04-01
- Volume
- 70
- Issue
- 4
- Pages
- 488
- ISSN
- 2168-6149
- PMC
- PMC3771392
- Cited by
- 106
- References
- 12
- Language
- en
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