Abnormalities of Plasma Volume in Borderline Hypertension
Abstract
Patients with borderline hypertension have decreased plasma volume. This is a reproducible finding. Decreased plasma volume is associated with increases of the hematocrit reading. Increased cardiac output and heart rates were observed in borderline hypertension, but this was not associated with the decrease of the plasma volume. However, the decreased plasma volume was correlated with increases of the blood pressure and of the total peripheral resistance. Since the decrease of plasma volume clearly relates to indices of "severity" of borderline hypertension (blood pressure and resistance), measurement of plasma volume may be important for understanding the natural history of the disease and for the assessment of an individual's risks.
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Untreated normal-weight essential hypertension patients have reduced plasma volume.
“in normal-weight patients, who untreated have reduced plasma volume, 110”
From Obesity Paradox in Hypertension: Is This Because Sympathetic Activation in Obesity-Hypertension Takes a Benign Form? (2018) · cites this paper as [110]
Cites
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Sympathetic overactivity in hypertension. A moving target
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Self-citationIs hypertension more benign when associated with obesity?
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Self-citation
- Authors
- Julius, S.
- Corresponding author
- Julius, Stevo
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1971-01-01
- Volume
- 127
- Issue
- 1
- Pages
- 116
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2059295172
- Cited by
- 157
- References
- 12
- Citations by year
- 2025: 1 · 2022: 1 · 2018: 3 · 2017: 3 · 2016: 10 · 2015: 1 · 2013: 17 · 2012: 18
- FWCI
- 6.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Keywords
- borderline hypertension, plasma volume, hematocrit, cardiac output, heart rate, systemic vascular resistance, blood pressure, hypertension severity, cardiovascular risk assessment
- MeSH terms
- Adult, Age Factors, Analysis of Variance, Blood Pressure Determination, Blood Volume Determination, Body Weight, Cardiac Output, Heart Rate, Hematocrit, Humans, Hypertension, Male, Plasma Volume, Vascular Resistance
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