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Effect of Transcranial Magnetic Stimulation on Action Naming in Patients With Alzheimer Disease

Open access
Cotelli, Maria, Manenti, Rosa, Cappa, Stefano F., Geroldi, Cristina, Zanetti, Orazio, Rossini, Paolo M., Miniussi, Carlo·2006·Archives of Neurology

Abstract

OBJECTIVE: To assess the effect of repetitive transcranial magnetic stimulation (rTMS) to the dorsolateral prefrontal cortex (DLPFC) on picture naming in patients with Alzheimer disease (AD). DESIGN: Experimental study. Patients with AD underwent rTMS in real and control conditions during picture-naming tasks. SETTING: San Giovanni di Dio Fatebenefratelli Scientific Institute in Brescia, Italy. Patients Fifteen patients with probable AD. Intervention High-frequency rTMS was applied to the left and right DLPFC during object and action naming. MAIN OUTCOME MEASURES: Language ability was assessed by accuracy of verbal response during online rTMS. RESULTS: Stimulation to the left and right DLPFC improved accuracy in action naming. CONCLUSIONS: These findings indicate that rTMS to the DLPFC, which speeds up action naming in normal controls, improves performance in patients with AD. While the mechanisms of rTMS-induced naming facilitation in these patients are unknown, the procedure may be worth testing as a novel approach to the treatment of language dysfunction.

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Metadata

Authors
Cotelli, M., Manenti, R., Cappa, S. F., Geroldi, C., Zanetti, O., Rossini, P. M., & Miniussi, C.
Venue
Archives of Neurology
Published
2006-11-01
Volume
63
Issue
11
Pages
1602
ISSN
0003-9942 (ISSN-L)
OpenAlex
W2014140896
Cited by
228
References
1
FWCI
2.97
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Effect of Transcranial Magnetic Stimulation on Action Naming in Patients With Alzheimer Disease. https://app.cochat.ai/papers/10.1001/archneur.63.11.1602
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Cotelli, M., Manenti, R., Cappa, S. F., Geroldi, C., Zanetti, O., Rossini, P. M., & Miniussi, C. (2006). Effect of Transcranial Magnetic Stimulation on Action Naming in Patients With Alzheimer Disease. Archives of Neurology. https://doi.org/10.1001/archneur.63.11.1602

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