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PRELIMINARY ANALYSIS OF FUNCTIONS OF THE TEMPORAL LOBES IN MONKEYS
Abstract
In previous communications1we pointed out that the chief symptoms following bilateral temporal lobectomy in the rhesus monkey consist in "psychic blindness" (Seelenblindheit) or visual agnosia, strong "oral" tendencies and profound emotional changes. Our results were primarily based on an analysis of the behavioral symptoms of a female rhesus monkey which had been studied for a period of four months following the operations. The type of disturbance analyzed in that case seemed to be similar to the "associative mind blindness" of Lissauer.2It is true that the diagnosis "agnosia" can be only of practical importance and merely serves to raise a number of questions. A review of the clinical literature indicates that the more carefully a case is studied the more difficult it may be to decide whether there is really an "agnostic" or merely a "visual" defect, that is, whether the variety of "agnostic" symptoms can be
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“This goes back to the original findings of hypersexuality in individuals with frontal lobe damage or Kluver-Bucy syndrome.94”
From Assessment and treatment of compulsive sexual behavior disorder: a sexual medicine perspective (2024) · cites this paper as [94]
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“For example, the amygdala has been associated with fear for decades, from studies of Kluver – Bucy syndrome, where fear reactivity is reduced due to amygdala lesions (Klüver & Bucy, 1939; LeDoux, 2007).”
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“Klüver and Bucy [8,9] described the following peculiar symptoms in rhesus monkeys after the removal of both temporal lobes including the uncus and hippocampus: 1) psychic blindness, 2) oral tendencies, 3)hypermetamorphosis , 4) emotional changes, 5) changes in sexual behavior.”
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“The amygdala is a heterogeneous collection of nuclei important for social-emotional processing, and is dysregulated in various neuropsychiatric diseases (Klüver & Bucy, 1939; LeDoux, 2000; Nishijo, Ono, & Nishino, 1988; Schumann, Bauman, & Amaral, 2011).”
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“However, deeper medial structures were not excised because Bailey feared producing deficits resembling the Kluver-Bucy syndrome.(42,43) In addition, Bailey seems to have believed that the anterolateral temporal lobe was the major source of psychomotor (partial complex) seizures.”
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“Apathy consists of reduced goal-directed behavior and is common after lesions to the vmPFC or with temporal lobes (see e.g., (Klu¨ver & Bucy, 1939; Lilly et al., 1983)).”
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“We appear to be one step closer to understanding mechanistically what Klüver and Bucy observed [11] on the notable relationship between amygdala and social behavior.”
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“KluvereBucy syndrome (KBS) is characterized by a constellation of neuropsychiatric symptoms, such as visual agnosia (prosopagnosia), hypermetamorphosis, placidity, hypersexuality, and hyperorality, initially observed in a rhesus monkey after bilateral temporal lobotomy [1].”
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“Klüver-Bucy syndrome (KBS) is a constellation of cognitive dysfunction including the inability to recognize the emotional significance of objects, hypersexuality, altered emotional behavior (particularly placidity), hyperorality, hypermetamorphosis (the tendency to react to every visual stimulus) and amnesia (anterogr…”
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“Klüver and Bucy [1,2] described the following peculiar syndrome in rhesus monkeys after removal of both temporal lobes, including the uncus and hippocampus: psychic blindness, oral tendencies, hypermetamorphosis, emotional changes, and increased sexual behavior.”
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“Kluver–Bucy syndrome (KBS) is a rare neurobehavioral condition characterized by visual agnosia, excessive oral tendency, hypermetamorphosis, placidity, altered sexual behaviors, and changes in dietary habits.”
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“Back in 1939, Klüver and Bucy [53] observed (in monkeys) that lesioning in the temporal lobe and amygdala led to extreme emotional changes, including loss of fear responses, failure to learn from aversive stimuli, and increased sexual behavior (leading to what is called Klüver-Bucy syndrome in…”
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“The role of temporal lobe in aggression was first described when Kluver and Bucy performed bilateral temporal lobectomy in rhesus monkeys and reported enhanced aggressive behavior [7].”
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“Both alterations seem to be present in Rhesus monkeys affected by the Klüver‐Bucy syndrome [20].”
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“In addition, Kluver and Bucy (1939) included a description of an absence of both anger and fear responses.”
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Metadata
- Authors
- KLÜVER, H.
- Corresponding author
- KLÜVER, HEINRICH
- Venue
- Archives of Neurology And Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1939-12-01
- Volume
- 42
- Issue
- 6
- Pages
- 979
- ISSN
- 0096-6754 (ISSN-L)
- OpenAlex
- W2169771257
- Cited by
- 1,696
- References
- 0
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 22 · 2023: 9 · 2022: 11 · 2021: 27 · 2020: 21 · 2019: 16 · 2018: 25 · 2017: 27 · 2016: 26 · 2015: 34 · 2014: 32 · 2013: 43 · 2012: 39
- FWCI
- 2.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Neurology And Psychiatry (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Neurology › Neurology and Historical Studies
- Keywords
- temporal lobe, rhesus monkeys, visual agnosia, emotional change, behavioral symptoms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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