Cited by 409Retinal Diseases and TreatmentsRetinal and Macular SurgeryOcular Diseases and Behçet’s Syndrome

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Argon Laser Photocoagulation for Senile Macular Degeneration: Results of a Randomized Clinical Trial

·1982·Archives of Ophthalmology

DOI 10.1001/archopht.1982.01030030920003

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Abstract

The Senile Macular Degeneration Study (SMDS) is a multicenter controlled clinical trial designed to answer the question, "Is argon laser photocoagulation useful in preventing severe visual loss in eyes with evidence of senile macular degeneration and a choroidal neovascular membrane outside the fovea?" Eligible patients were assigned randomly to a "treatment" group or a "no treatment" group. Recruitment in the SMDS has been terminated because, after 18 months of follow-up, 60% of untreated eyes v 25% of treated eyes had experienced severe visual loss. Follow-up of all patients continues to assess long-term results of treatment. Patients with senile macular degeneration who are at risk for the development of choroidal neovascularization should be examined periodically so that if symptomatic neovascularization develops, treatment can be considered before irreversible visual loss occurs.

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Venue: Archives of Ophthalmology
Publisher: American Medical Association (AMA)
Published: 1982-06-01
Volume: 100
Issue: 6
Pages: 912
ISSN: 0003-9950 (ISSN-L)
DOI: 10.1001/archopht.1982.01030030920003
OpenAlex: W4243472760
Cited by: 405
References: 0
Citations by year: 2026: 1 · 2025: 4 · 2024: 4 · 2023: 1 · 2022: 3 · 2021: 6 · 2020: 6 · 2019: 1 · 2018: 2 · 2017: 6 · 2016: 5 · 2015: 4 · 2014: 13 · 2013: 5 · 2012: 13
FWCI: 25.31
Type: journal article
Language: en
Open access: closed
Locations: Archives of Ophthalmology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
Health Sciences › Medicine › Ophthalmology › Retinal and Macular Surgery
Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
Keywords: argon laser photocoagulation, senile macular degeneration, choroidal neovascularization, blindness prevention
MeSH terms: Aged, Clinical Trials as Topic, Fluorescein Angiography, Follow-Up Studies, Humans, Lasers, Macular Degeneration, Middle Aged, Random Allocation, Vision Disorders, Laser Therapy

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Argon Laser Photocoagulation for Senile Macular Degeneration: Results of a Randomized Clinical Trial

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